Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BEN15_RS04720 Genome accession   NZ_CP016877
Coordinates   882612..883301 (+) Length   229 a.a.
NCBI ID   WP_065972913.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 877612..888301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS11610 - 878578..878748 (+) 171 Protein_852 ascorbate 6-phosphate lactonase -
  BEN15_RS04700 (BEN15_04700) - 878765..879436 (-) 672 WP_065972910.1 potassium channel family protein -
  BEN15_RS04705 (BEN15_04705) - 879476..880840 (-) 1365 WP_082308126.1 TrkH family potassium uptake protein -
  BEN15_RS04710 (BEN15_04710) rsmG 880910..881623 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BEN15_RS04715 (BEN15_04715) - 881920..882456 (+) 537 WP_065972912.1 DUF177 domain-containing protein -
  BEN15_RS04720 (BEN15_04720) covR 882612..883301 (+) 690 WP_065972913.1 response regulator transcription factor Regulator
  BEN15_RS04725 (BEN15_04725) covS 883298..884815 (+) 1518 WP_065972914.1 HAMP domain-containing sensor histidine kinase Regulator
  BEN15_RS04730 (BEN15_04730) nrdR 884937..885416 (+) 480 WP_065972915.1 transcriptional regulator NrdR -
  BEN15_RS04735 (BEN15_04735) - 885413..886588 (+) 1176 WP_011680739.1 DnaD domain protein -
  BEN15_RS04740 (BEN15_04740) dnaI 886592..887494 (+) 903 WP_065972916.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26629.73 Da        Isoelectric Point: 4.7834

>NTDB_id=193309 BEN15_RS04720 WP_065972913.1 882612..883301(+) (covR) [Streptococcus thermophilus strain KLDS 3.1003]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKHDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=193309 BEN15_RS04720 WP_065972913.1 882612..883301(+) (covR) [Streptococcus thermophilus strain KLDS 3.1003]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACTTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAACA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

44.828

100

0.454
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment