Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   BEN15_RS04725 Genome accession   NZ_CP016877
Coordinates   883298..884815 (+) Length   505 a.a.
NCBI ID   WP_065972914.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 878298..889815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS11610 - 878578..878748 (+) 171 Protein_852 ascorbate 6-phosphate lactonase -
  BEN15_RS04700 (BEN15_04700) - 878765..879436 (-) 672 WP_065972910.1 potassium channel family protein -
  BEN15_RS04705 (BEN15_04705) - 879476..880840 (-) 1365 WP_082308126.1 TrkH family potassium uptake protein -
  BEN15_RS04710 (BEN15_04710) rsmG 880910..881623 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BEN15_RS04715 (BEN15_04715) - 881920..882456 (+) 537 WP_065972912.1 DUF177 domain-containing protein -
  BEN15_RS04720 (BEN15_04720) covR 882612..883301 (+) 690 WP_065972913.1 response regulator transcription factor Regulator
  BEN15_RS04725 (BEN15_04725) covS 883298..884815 (+) 1518 WP_065972914.1 HAMP domain-containing sensor histidine kinase Regulator
  BEN15_RS04730 (BEN15_04730) nrdR 884937..885416 (+) 480 WP_065972915.1 transcriptional regulator NrdR -
  BEN15_RS04735 (BEN15_04735) - 885413..886588 (+) 1176 WP_011680739.1 DnaD domain protein -
  BEN15_RS04740 (BEN15_04740) dnaI 886592..887494 (+) 903 WP_065972916.1 primosomal protein DnaI -
  BEN15_RS04745 (BEN15_04745) der 887600..888910 (+) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -
  BEN15_RS11280 (BEN15_04750) - 888974..889645 (+) 672 Protein_863 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57590.89 Da        Isoelectric Point: 5.2673

>NTDB_id=193310 BEN15_RS04725 WP_065972914.1 883298..884815(+) (covS) [Streptococcus thermophilus strain KLDS 3.1003]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGDLAHNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=193310 BEN15_RS04725 WP_065972914.1 883298..884815(+) (covS) [Streptococcus thermophilus strain KLDS 3.1003]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGTATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCACATAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACTC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

95.02

99.406

0.945

Multiple sequence alignment