Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BEN15_RS04010 Genome accession   NZ_CP016877
Coordinates   750383..751132 (+) Length   249 a.a.
NCBI ID   WP_065972842.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 745383..756132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS11230 - 745948..746118 (+) 171 WP_011680664.1 hypothetical protein -
  BEN15_RS10255 - 746205..746312 (+) 108 WP_082308124.1 LPXTG cell wall anchor domain-containing protein -
  BEN15_RS03995 (BEN15_03995) - 746398..747138 (-) 741 WP_065972838.1 amino acid ABC transporter ATP-binding protein -
  BEN15_RS04000 (BEN15_04000) - 747138..748688 (-) 1551 WP_065972839.1 ABC transporter substrate-binding protein/permease -
  BEN15_RS04005 (BEN15_04005) - 748891..749745 (+) 855 WP_041828107.1 undecaprenyl-diphosphate phosphatase -
  BEN15_RS10260 - 749797..750105 (-) 309 WP_335743668.1 DUF3021 family protein -
  BEN15_RS04010 (BEN15_04010) mecA 750383..751132 (+) 750 WP_065972842.1 adaptor protein MecA Regulator
  BEN15_RS04015 (BEN15_04015) - 751136..752293 (+) 1158 WP_065972844.1 glycosyltransferase family 4 protein -
  BEN15_RS04020 (BEN15_04020) sufC 752454..753224 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  BEN15_RS04025 (BEN15_04025) sufD 753261..754523 (+) 1263 WP_002947640.1 Fe-S cluster assembly protein SufD -
  BEN15_RS04030 (BEN15_04030) - 754577..755809 (+) 1233 WP_065972845.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29167.69 Da        Isoelectric Point: 4.0481

>NTDB_id=193301 BEN15_RS04010 WP_065972842.1 750383..751132(+) (mecA) [Streptococcus thermophilus strain KLDS 3.1003]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=193301 BEN15_RS04010 WP_065972842.1 750383..751132(+) (mecA) [Streptococcus thermophilus strain KLDS 3.1003]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

99.197

100

0.992
  mecA Streptococcus thermophilus LMG 18311

99.197

100

0.992
  mecA Streptococcus mutans UA159

57.787

97.992

0.566
  mecA Streptococcus pneumoniae Rx1

46.586

100

0.466
  mecA Streptococcus pneumoniae D39

46.586

100

0.466
  mecA Streptococcus pneumoniae R6

46.586

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.586

100

0.466

Multiple sequence alignment