Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CA930_RS06250 Genome accession   NZ_CP021263
Coordinates   1378842..1379519 (-) Length   225 a.a.
NCBI ID   WP_011213604.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. fraseri strain D-3137     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1373842..1384519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA930_RS06225 ruvC 1374005..1374529 (+) 525 WP_027226814.1 crossover junction endodeoxyribonuclease RuvC -
  CA930_RS06230 ruvA 1374526..1375125 (+) 600 WP_027226815.1 Holliday junction branch migration protein RuvA Machinery gene
  CA930_RS06235 - 1375184..1375504 (+) 321 WP_027226816.1 hypothetical protein -
  CA930_RS06240 lem8 1375582..1377141 (-) 1560 WP_027226817.1 Dot/Icm T4SS effector Lem8 -
  CA930_RS06245 - 1377430..1378845 (-) 1416 WP_027226818.1 ATP-binding protein -
  CA930_RS06250 ciaR 1378842..1379519 (-) 678 WP_011213604.1 response regulator Regulator
  CA930_RS06255 - 1379580..1380125 (-) 546 WP_027221489.1 septation protein A -
  CA930_RS06260 - 1380369..1381808 (-) 1440 WP_027226819.1 LysM peptidoglycan-binding domain-containing protein -
  CA930_RS06265 gloB 1381922..1382686 (-) 765 WP_027226820.1 hydroxyacylglutathione hydrolase -
  CA930_RS06270 rlmJ 1382690..1383538 (-) 849 WP_027226821.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  CA930_RS06275 - 1383677..1383886 (+) 210 WP_011213609.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25151.74 Da        Isoelectric Point: 4.9981

>NTDB_id=191598 CA930_RS06250 WP_011213604.1 1378842..1379519(-) (ciaR) [Legionella pneumophila subsp. fraseri strain D-3137]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=191598 CA930_RS06250 WP_011213604.1 1378842..1379519(-) (ciaR) [Legionella pneumophila subsp. fraseri strain D-3137]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGTGATGCAGTAAAAGCCGGATTGACACAATTTGGGTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCGCGAGCAGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTACAAAACATCAGACATGATGGAAATTCCACACCTGTCATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGAGTAAAAGGTTTAGATAGTGGCGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCCTTGGTAAGGCGCTCTCAGGGTAGAGCTGATTCAGTGTTGCAATATAAAAATATTACCC
TTGATCCAGCCGCTCATTCTGTATTCGTGGATGATGTTCTCGTCAATGTTCCAAGAAGAGAATTCGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGTCAAGTCTTATCTCGAGAACAATTAATGCAGAGTATTTATGGTTGGGAAGAAGACGTGGACAG
CAATGCTCTTGAGGTTCATATCCATAATTTACGTAAAAAACTTAATGCAAACTTTATCCGCACTATTCGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-215)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae D39

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae R6

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae TIGR4

38.356

97.333

0.373
  ciaR Streptococcus mutans UA159

37.9

97.333

0.369
  micA Streptococcus pneumoniae Cp1015

35.345

100

0.364