Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BCR17_RS03245 Genome accession   NZ_CP016598
Coordinates   666494..667633 (-) Length   379 a.a.
NCBI ID   WP_029510324.1    Uniprot ID   -
Organism   Leuconostoc lactis strain WiKim40     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 661494..672633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BCR17_RS03210 (BCR17_03210) - 661737..662072 (-) 336 WP_010004867.1 PadR family transcriptional regulator -
  BCR17_RS03225 (BCR17_03225) - 662466..662852 (-) 387 WP_029510329.1 DUF6508 domain-containing protein -
  BCR17_RS03230 (BCR17_03230) - 662898..664001 (-) 1104 WP_029510327.1 AI-2E family transporter -
  BCR17_RS03235 (BCR17_03235) mutY 664007..665023 (-) 1017 WP_068851016.1 A/G-specific adenine glycosylase -
  BCR17_RS08935 - 665147..665290 (+) 144 WP_010000998.1 hypothetical protein -
  BCR17_RS03240 (BCR17_03240) rlmH 665363..665842 (-) 480 WP_010000997.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BCR17_RS03245 (BCR17_03245) htrA 666494..667633 (-) 1140 WP_029510324.1 S1C family serine protease Regulator
  BCR17_RS03250 (BCR17_03250) yycI 667696..668472 (-) 777 WP_068851019.1 two-component system regulatory protein YycI -
  BCR17_RS03255 (BCR17_03255) yycH 668498..669808 (-) 1311 WP_068851024.1 two-component system activity regulator YycH -
  BCR17_RS03260 (BCR17_03260) walK 669798..671669 (-) 1872 WP_068851028.1 cell wall metabolism sensor histidine kinase WalK -
  BCR17_RS03265 (BCR17_03265) yycF 671765..672472 (-) 708 WP_029510319.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39316.69 Da        Isoelectric Point: 9.1970

>NTDB_id=189525 BCR17_RS03245 WP_029510324.1 666494..667633(-) (htrA) [Leuconostoc lactis strain WiKim40]
MADKSLTKIIVTGAVAGVLGGGAMLYGQRGLEDMQQSQQKVTTKADKTVTIAKDATATSAYNKVSDAVVSVLNFSQTGKD
SFQEASEGSGVIYKKSGDAAYVVTNNHVINGAAQIQVMLHDGQKVTATLVGKDAMTDLAVLKIAADKVTTTAAFGDSNKI
QVGQKVLAIGSPLGSQYASSVTEGIISAKKRLVESSSEDGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSASGTSVEGMGFAIPSNQVVDIVNKLVKYGQVTRPAIGIGLVELSAVTVDDQKSLLKIPDTVKGGVVVMSLTPNGPAAK
AGIQKYDVITGIDGKTVTGQADLREELYKHDLNDTVTITYYHQAEKKTVKVKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=189525 BCR17_RS03245 WP_029510324.1 666494..667633(-) (htrA) [Leuconostoc lactis strain WiKim40]
ATGGCAGATAAATCATTAACAAAAATTATCGTAACCGGCGCAGTTGCTGGCGTTCTTGGTGGTGGGGCGATGTTGTATGG
GCAGCGCGGCTTAGAAGATATGCAACAATCACAACAAAAAGTCACCACCAAGGCTGATAAGACGGTGACAATTGCCAAGG
ATGCAACGGCGACTTCAGCTTACAATAAAGTGTCAGATGCGGTTGTTTCTGTGTTGAATTTCTCCCAAACAGGGAAGGAT
TCGTTTCAAGAAGCATCTGAAGGTTCAGGCGTGATTTACAAGAAGTCTGGGGATGCGGCCTATGTGGTGACGAATAATCA
CGTGATTAACGGAGCAGCCCAAATTCAAGTCATGTTACATGATGGGCAAAAAGTGACGGCTACGTTGGTTGGAAAGGATG
CCATGACGGATTTAGCGGTGTTAAAGATCGCGGCCGATAAGGTGACCACAACGGCCGCATTTGGTGATTCCAATAAAATC
CAAGTAGGGCAGAAAGTTTTGGCTATTGGCTCGCCGTTAGGGTCACAATATGCGTCATCGGTGACAGAAGGGATTATTTC
GGCTAAGAAGCGTTTGGTGGAGTCTTCTTCTGAAGATGGGCAAAATTATGGGGGCTCAACGGTTATTCAAACTGATGCGG
CCATTAACCCTGGTAACTCCGGTGGTCCATTAATTAATTTTGCTGGCCAAGTGATTGGGATTAACTCAATGAAACTCTCT
TCTTCTGCTTCTGGCACGAGTGTTGAAGGGATGGGATTTGCTATTCCGTCAAATCAAGTGGTGGATATTGTTAATAAGTT
GGTCAAGTATGGTCAAGTGACGCGTCCAGCTATTGGCATTGGATTAGTTGAATTATCAGCTGTGACGGTTGATGACCAAA
AGTCACTGTTGAAGATCCCAGATACAGTTAAGGGCGGCGTTGTTGTCATGAGTTTGACTCCTAATGGACCAGCGGCTAAA
GCTGGTATTCAGAAATACGACGTGATTACTGGGATTGATGGCAAAACCGTGACGGGGCAAGCTGACTTGCGTGAAGAATT
ATATAAGCATGATCTTAATGATACGGTCACAATTACTTATTATCACCAAGCAGAGAAAAAGACTGTTAAAGTTAAATTAA
CACAAAAATTAGGAAGTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.532

100

0.483
  htrA Streptococcus gordonii str. Challis substr. CH1

47.23

100

0.472
  htrA Streptococcus pneumoniae D39

50.893

88.654

0.451
  htrA Streptococcus pneumoniae TIGR4

50.893

88.654

0.451
  htrA Streptococcus pneumoniae R6

50.893

88.654

0.451
  htrA Streptococcus pneumoniae Rx1

50.893

88.654

0.451
  htrA Streptococcus mutans UA159

49.412

89.71

0.443

Multiple sequence alignment