Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BBD27_RS02735 Genome accession   NZ_CP016394
Coordinates   522488..523177 (-) Length   229 a.a.
NCBI ID   WP_002949638.1    Uniprot ID   A0A060BFD8
Organism   Streptococcus thermophilus strain ND07     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 517488..528177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BBD27_RS02715 (BBD27_0545) dnaI 518295..519197 (-) 903 WP_014607971.1 primosomal protein DnaI -
  BBD27_RS02720 (BBD27_0546) - 519201..520376 (-) 1176 WP_011680739.1 DnaD domain protein -
  BBD27_RS02725 (BBD27_0547) nrdR 520373..520852 (-) 480 WP_011680738.1 transcriptional regulator NrdR -
  BBD27_RS02730 (BBD27_0548) covS 520974..522491 (-) 1518 WP_002949640.1 HAMP domain-containing sensor histidine kinase Regulator
  BBD27_RS02735 (BBD27_0549) covR 522488..523177 (-) 690 WP_002949638.1 response regulator transcription factor Regulator
  BBD27_RS02740 (BBD27_0550) - 523333..523869 (-) 537 WP_014607968.1 DUF177 domain-containing protein -
  BBD27_RS02745 (BBD27_0551) rsmG 524166..524879 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BBD27_RS02750 (BBD27_0552) - 524949..526313 (+) 1365 WP_011680735.1 TrkH family potassium uptake protein -
  BBD27_RS02755 (BBD27_0553) - 526353..527024 (+) 672 WP_002946492.1 potassium channel family protein -
  BBD27_RS11360 - 527041..527211 (-) 171 Protein_534 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26655.77 Da        Isoelectric Point: 4.7059

>NTDB_id=187827 BBD27_RS02735 WP_002949638.1 522488..523177(-) (covR) [Streptococcus thermophilus strain ND07]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=187827 BBD27_RS02735 WP_002949638.1 522488..523177(-) (covR) [Streptococcus thermophilus strain ND07]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACTTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BFD8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

96.07

100

0.961
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment