Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   A9176_RS01745 Genome accession   NZ_CP016329
Coordinates   347805..348944 (-) Length   379 a.a.
NCBI ID   WP_077281977.1    Uniprot ID   -
Organism   Leuconostoc garlicum strain KFRI01     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 342805..353944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9176_RS01710 (A9176_01690) - 343049..343384 (-) 336 WP_048700375.1 PadR family transcriptional regulator -
  A9176_RS01725 (A9176_01705) - 343778..344164 (-) 387 WP_077281973.1 DUF6508 domain-containing protein -
  A9176_RS01730 (A9176_01710) - 344210..345313 (-) 1104 WP_077281974.1 AI-2E family transporter -
  A9176_RS01735 (A9176_01715) mutY 345319..346335 (-) 1017 WP_077281975.1 A/G-specific adenine glycosylase -
  A9176_RS08800 - 346459..346602 (+) 144 WP_010000998.1 hypothetical protein -
  A9176_RS01740 (A9176_01720) rlmH 346674..347153 (-) 480 WP_077281976.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A9176_RS01745 (A9176_01725) htrA 347805..348944 (-) 1140 WP_077281977.1 trypsin-like peptidase domain-containing protein Regulator
  A9176_RS01750 (A9176_01730) yycI 349007..349783 (-) 777 WP_077281978.1 two-component system regulatory protein YycI -
  A9176_RS01755 (A9176_01735) yycH 349809..351119 (-) 1311 WP_077281979.1 two-component system activity regulator YycH -
  A9176_RS01760 (A9176_01740) walK 351109..352980 (-) 1872 WP_068851028.1 cell wall metabolism sensor histidine kinase WalK -
  A9176_RS01765 (A9176_01745) yycF 353077..353784 (-) 708 WP_029510319.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39328.74 Da        Isoelectric Point: 9.1970

>NTDB_id=186966 A9176_RS01745 WP_077281977.1 347805..348944(-) (htrA) [Leuconostoc garlicum strain KFRI01]
MADKSLTKIIVTGAVAGVLGGGAMLYGQRGLEDMQQSQQKVTTKADKTVTIAKDATATSAYNKVSDAVVSVLNFSQTGKD
SFQEASEGSGVIYKKSGDAAYVVTNNHVINGAAQIQVMLHDGQKVTATLVGKDAMTDLAVLKIAADKVTTTAAFGDSNKI
QVGQKVLAIGSPLGSQYASSVTEGIISAKKRLVESSSEDGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSASGTSVEGMGFAIPSNQVVDIVNKLVKYGQVTRPAIGIGLVELSAVTVDDQKSLLKIPDTVKGGVVVMSLIPNGPAAK
AGIQKYDVITGIDGKTVTGQADLREELYKHDLNDTVTITYYHQAEKKTVKVKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=186966 A9176_RS01745 WP_077281977.1 347805..348944(-) (htrA) [Leuconostoc garlicum strain KFRI01]
ATGGCAGATAAATCATTAACAAAAATTATCGTAACCGGCGCAGTTGCTGGCGTTCTTGGTGGTGGGGCGATGTTGTATGG
GCAGCGCGGCTTAGAAGATATGCAACAATCACAACAAAAAGTCACCACCAAGGCTGATAAGACGGTGACAATTGCCAAGG
ATGCAACGGCGACTTCAGCTTACAATAAAGTGTCAGATGCGGTTGTTTCTGTGTTGAATTTCTCTCAAACGGGCAAAGAT
TCTTTTCAAGAAGCGTCTGAAGGCTCAGGCGTGATTTACAAGAAGTCTGGGGATGCGGCCTATGTGGTGACGAATAATCA
CGTGATTAACGGAGCAGCCCAAATTCAAGTCATGTTACATGATGGGCAAAAAGTGACGGCTACGTTGGTTGGAAAGGATG
CCATGACGGATTTAGCGGTGTTAAAGATCGCTGCCGATAAGGTTACCACAACGGCAGCATTTGGTGATTCCAATAAGATC
CAAGTAGGTCAGAAAGTTTTGGCTATTGGCTCGCCGTTAGGGTCACAATATGCGTCATCGGTGACAGAAGGGATTATTTC
GGCTAAGAAGCGTTTGGTGGAGTCTTCTTCTGAAGATGGGCAAAATTATGGGGGCTCAACGGTTATTCAAACTGATGCGG
CCATTAACCCTGGTAATTCCGGTGGTCCATTAATTAATTTTGCTGGCCAAGTGATTGGGATTAACTCAATGAAACTCTCT
TCTTCTGCTTCTGGCACGAGTGTTGAAGGGATGGGATTTGCTATTCCGTCAAATCAAGTGGTGGATATTGTTAATAAGTT
GGTCAAGTATGGCCAAGTGACGCGTCCAGCTATTGGCATTGGATTAGTTGAATTATCAGCTGTGACGGTTGATGACCAAA
AGTCGCTGTTGAAGATCCCAGATACAGTTAAGGGCGGCGTTGTTGTCATGAGTTTGATCCCTAATGGACCAGCGGCTAAA
GCTGGTATTCAGAAATACGACGTAATTACTGGAATTGATGGTAAAACCGTGACGGGGCAAGCTGACTTGCGTGAAGAATT
ATATAAGCATGATCTTAATGATACGGTCACAATTACTTATTATCACCAAGCAGAGAAAAAGACTGTTAAAGTTAAATTAA
CACAAAAATTAGGAAGTTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

PDZ domain (PDZ_2)

(276-373)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.532

100

0.483
  htrA Streptococcus gordonii str. Challis substr. CH1

46.966

100

0.47
  htrA Streptococcus pneumoniae D39

50.893

88.654

0.451
  htrA Streptococcus pneumoniae TIGR4

50.893

88.654

0.451
  htrA Streptococcus pneumoniae R6

50.893

88.654

0.451
  htrA Streptococcus pneumoniae Rx1

50.893

88.654

0.451
  htrA Streptococcus mutans UA159

49.118

89.71

0.441

Multiple sequence alignment