Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   A6J87_RS06205 Genome accession   NZ_CP020451
Coordinates   1200269..1201012 (+) Length   247 a.a.
NCBI ID   WP_037600060.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1195269..1206012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS06185 (A6J87_06160) - 1195368..1196675 (+) 1308 WP_002885760.1 GHKL domain-containing protein -
  A6J87_RS06190 (A6J87_06165) - 1196735..1197625 (+) 891 WP_014635088.1 hypothetical protein -
  A6J87_RS06195 (A6J87_06170) - 1197647..1198927 (+) 1281 WP_105257718.1 hypothetical protein -
  A6J87_RS06200 (A6J87_06175) - 1198951..1200267 (+) 1317 WP_080611758.1 GHKL domain-containing protein -
  A6J87_RS06205 (A6J87_06180) comE/blpR 1200269..1201012 (+) 744 WP_037600060.1 LytTR family DNA-binding domain-containing protein Regulator
  A6J87_RS06210 (A6J87_06185) - 1201954..1203153 (+) 1200 WP_037598503.1 argininosuccinate synthase -
  A6J87_RS06215 (A6J87_06190) argH 1203480..1204865 (+) 1386 WP_037601513.1 argininosuccinate lyase -
  A6J87_RS06220 (A6J87_06195) rnpA 1204950..1205285 (+) 336 WP_037600055.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28478.75 Da        Isoelectric Point: 6.7586

>NTDB_id=186766 A6J87_RS06205 WP_037600060.1 1200269..1201012(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_259]
MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSGINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY
FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKSQLMIYFENGDSCPVSRLKMKALLKK
WSDVKEH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=186766 A6J87_RS06205 WP_037600060.1 1200269..1201012(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_259]
ATGAATATTTACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCAGAGAATTGGTTTCAGAGGG
CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCCCACAAACTATTGTCCGGTATCAACGAGAAGGGTAACCATC
AGGTTTTCCTTTTAGATATTGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT
GCTAATGCGGTTATTATTTTTGTGACAACTCACTCAGAGTTTGCACCGATTAGTTTTAAATACAAGGTTTCTGCGTTAGA
TTTTATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTAAATCAAAAAGTTG
GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACAGCACAGTCTCGAATCCAAGTCCCTATGAGAGATATTTATTAT
TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTGATTACCAAAACAGAGCGTTTGGAGTTTTATGCCAATCTTGGAGA
TATTACTTCGGTGAATAAAAAACTCTTTTCTTGTCATCGTTCGTTTTTAGTTAATTTGGATAATATTTCTCGTATTGATA
AGAGTCAGTTGATGATTTACTTTGAGAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCTTGCTTAAAAAA
TGGTCAGATGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.5

97.166

0.462
  comE/comE2 Streptococcus equinus JB1

42.857

99.19

0.425
  comE/comE1 Streptococcus equinus JB1

40.909

97.976

0.401
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.759

97.571

0.368
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.759

97.571

0.368