Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A6J87_RS03880 Genome accession   NZ_CP020451
Coordinates   789799..790548 (-) Length   249 a.a.
NCBI ID   WP_070576236.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 784799..795548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS03860 (A6J87_03845) - 785121..786353 (-) 1233 WP_070576233.1 cysteine desulfurase -
  A6J87_RS03865 (A6J87_03850) sufD 786407..787669 (-) 1263 WP_048790376.1 Fe-S cluster assembly protein SufD -
  A6J87_RS03870 (A6J87_03855) sufC 787706..788476 (-) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  A6J87_RS03875 (A6J87_03860) - 788638..789795 (-) 1158 WP_037598909.1 glycosyltransferase family 4 protein -
  A6J87_RS03880 (A6J87_03865) mecA 789799..790548 (-) 750 WP_070576236.1 adaptor protein MecA Regulator
  A6J87_RS03885 (A6J87_03870) - 790728..791126 (+) 399 WP_225791450.1 DUF3021 family protein -
  A6J87_RS03890 (A6J87_03875) - 791186..792040 (-) 855 WP_037598902.1 undecaprenyl-diphosphate phosphatase -
  A6J87_RS03895 (A6J87_03880) - 792246..793793 (+) 1548 WP_070576239.1 ABC transporter substrate-binding protein/permease -
  A6J87_RS03900 (A6J87_03885) - 793793..794533 (+) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29084.69 Da        Isoelectric Point: 4.0534

>NTDB_id=186737 A6J87_RS03880 WP_070576236.1 789799..790548(-) (mecA) [Streptococcus salivarius strain FDAARGOS_259]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKNVPVEGSELYKLGNVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=186737 A6J87_RS03880 WP_070576236.1 789799..790548(-) (mecA) [Streptococcus salivarius strain FDAARGOS_259]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTACACAAGGCTTGAAGAATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GAATGTCTACTATATGACAATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATTTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

94.378

100

0.944
  mecA Streptococcus thermophilus LMG 18311

93.574

100

0.936
  mecA Streptococcus mutans UA159

59.426

97.992

0.582
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474