Detailed information NTG0186505

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: A6J82_RS02710
• Genome accession: NZ_CP020449
• Coordinates: 468253..470829 (+)
• Length: 858 a.a.
• NCBI ID: WP_001118373.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain FDAARGOS_254
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 463253..475829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J82_RS02685 (A6J82_02705)	-	463499..464443 (+)	945	WP_000857770.1	YitT family protein	-
A6J82_RS02690 (A6J82_02710)	-	464551..465423 (+)	873	WP_000915474.1	YitT family protein	-
A6J82_RS02695 (A6J82_02715)	-	465450..465758 (-)	309	WP_001138859.1	bacteriocin immunity protein	-
A6J82_RS02700 (A6J82_02720)	argS	465846..467537 (-)	1692	WP_000379859.1	arginine--tRNA ligase	-
A6J82_RS02705 (A6J82_02725)	argR	467759..468196 (+)	438	WP_001033152.1	arginine repressor	-
A6J82_RS02710 (A6J82_02730)	hexA	468253..470829 (+)	2577	WP_001118373.1	DNA mismatch repair protein MutS	Machinery gene
A6J82_RS02715 (A6J82_02735)	-	470886..471089 (-)	204	WP_000191849.1	cold-shock protein	-
A6J82_RS02725 (A6J82_02745)	hexB	471315..473288 (+)	1974	WP_000034616.1	DNA mismatch repair endonuclease MutL	Machinery gene
A6J82_RS02730 (A6J82_02750)	-	473320..474552 (+)	1233	WP_000657480.1	MFS transporter	-
A6J82_RS02735 (A6J82_02755)	ruvA	474554..475144 (+)	591	WP_000272490.1	Holliday junction branch migration protein RuvA	Machinery gene
A6J82_RS02740 (A6J82_02760)	-	475167..475718 (+)	552	WP_000817342.1	DNA-3-methyladenine glycosylase I	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97025.69 Da
• Isoelectric Point: 4.8723

>NTDB_id=186505 A6J82_RS02710 WP_001118373.1 468253..470829(+) (hexA) [Streptococcus agalactiae strain FDAARGOS_254]
MAKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLAYMDVSTGEFQATLLTDFE
SVRSEILNLKAREIVVGYQLTDEKNHLLTKQMNLLLSYEDERLNDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQIPRIKMILQSFNQPELDIIVNKIDTMPELESLINTAIA
PEAQATITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEMLEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENHHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIEPGPADKSYGIHVAKIAGLPIDLLDRATDILSQLEADAVQLIVSAPQEA
VTADLNEELDPGKQQGQLSLFEEHSNAGRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide

• Length: 2577 bp

>NTDB_id=186505 A6J82_RS02710 WP_001118373.1 468253..470829(+) (hexA) [Streptococcus agalactiae strain FDAARGOS_254]
ATGGCCAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAAATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGAGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTCAAGCGTGAGGTAGT
GCAAGTTGTTACCCCAGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATATATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGTGAAATACTAAATTTAAAAGCTCGTGAGATTGTAGTAGGATATCAATTGACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTATCATACGAAGACGAACGACTTAATGATATTCATTTGATTGATGAGCAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTCGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACGAAAAATAGTCTAGATTTACTGGAGAATGC
TAGAACAAGCAAGAAGCATGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAACGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGCCTAGCAAGTAGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACAGACCTTATCACAAATTCCTCGAATTAAAATGATTTTACAGTCCTTCA
ATCAACCTGAGCTTGACATCATTGTCAACAAAATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGGCTACTATCACTGAGGGAAACATTATCAAGTCTGGATTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATTGGTACCCTTAAAATTG
ATTATAATAAAAAAGACGGCTATTACTTCCATGTGACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACATTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAATGCTCGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCTCAAGTAGAATCTTATATTAAACGTCTTCAAGAGTTAG
CAAAGACTATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATCATCACTATGTTCGTCCCAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACCGTTGAAAAAGTGATGGGAGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTTTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGATGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCGAA
TCAAGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATGACCGTGTTAGGGCAAAAACAATGTTTGCAACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGGCTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAACCTGGACCTGCGGACAAGTCTTATGGGATACACGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCAACTGATATTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCAGCCCCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAACTAGATCCTGGGAAGCAACAAGGACAATTATCGCTTTTTGAAGAACATTCAAATGC
AGGTAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGATT
TAAAGAAATTATTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-240)

• MutS domain V (MutS_V) (600-786)

• MutS domain III (MutS_III) (257-547)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (416-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	69.338	100	0.696
mutS	Pseudomonas stutzeri strain ATCC 17587	36.758	100	0.375