Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ALX04_RS13395 Genome accession   NZ_CP016270
Coordinates   2723091..2725241 (+) Length   716 a.a.
NCBI ID   WP_027821502.1    Uniprot ID   L7ZAH2
Organism   Lactiplantibacillus plantarum subsp. plantarum strain CGMCC 1.557     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2718091..2730241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ALX04_RS16170 - 2719037..2719204 (+) 168 WP_153302738.1 hypothetical protein -
  ALX04_RS13370 (ALX04_012850) - 2719222..2720562 (+) 1341 WP_088899883.1 GHKL domain-containing protein -
  ALX04_RS13375 (ALX04_012855) - 2720563..2721306 (+) 744 WP_015825122.1 response regulator transcription factor -
  ALX04_RS13380 (ALX04_012860) - 2721600..2722373 (-) 774 WP_027821503.1 CPBP family intramembrane glutamic endopeptidase -
  ALX04_RS13385 (ALX04_012865) plnF 2722472..2722630 (-) 159 WP_003643811.1 two-peptide bacteriocin plantaricin EF subunit PlnF -
  ALX04_RS13390 (ALX04_012870) plnE 2722655..2722825 (-) 171 WP_003641985.1 two-peptide bacteriocin plantaricin EF subunit PlnE -
  ALX04_RS13395 (ALX04_012875) comA 2723091..2725241 (+) 2151 WP_027821502.1 peptide cleavage/export ABC transporter Regulator
  ALX04_RS13400 (ALX04_012880) - 2725258..2726634 (+) 1377 WP_053339245.1 HlyD family secretion protein -
  ALX04_RS13405 (ALX04_012885) - 2726724..2727413 (+) 690 WP_053339246.1 CPBP family intramembrane glutamic endopeptidase -
  ALX04_RS13410 (ALX04_012890) - 2727481..2728149 (+) 669 WP_027821499.1 CPBP family intramembrane glutamic endopeptidase -
  ALX04_RS13415 (ALX04_012895) - 2728236..2728916 (+) 681 WP_053339247.1 CPBP family intramembrane glutamic endopeptidase -
  ALX04_RS13420 (ALX04_012900) - 2729010..2729696 (+) 687 WP_027821497.1 CPBP family intramembrane glutamic endopeptidase -
  ALX04_RS13425 (ALX04_012905) - 2729834..2730037 (+) 204 WP_027821496.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79956.67 Da        Isoelectric Point: 6.6530

>NTDB_id=186455 ALX04_RS13395 WP_027821502.1 2723091..2725241(+) (comA) [Lactiplantibacillus plantarum subsp. plantarum strain CGMCC 1.557]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFDVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVMLNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=186455 ALX04_RS13395 WP_027821502.1 2723091..2725241(+) (comA) [Lactiplantibacillus plantarum subsp. plantarum strain CGMCC 1.557]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGATGTCCAAGATTTACCATTG
CCATTCATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTTGTTGTAAAAACCTCGAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCTAATAATATGCACAGTACATTGGCAGTGGTGGCAATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCAAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAAAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTGCTTATTGATTTTTATCAGC
CGAATAGTGGTGATGTCATGCTGAACGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACAGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCTCCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAGAAACAATTAATCGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGCTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(5-140)

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB L7ZAH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

59.046

99.581

0.588
  comA Streptococcus pneumoniae Rx1

58.766

99.581

0.585
  comA Streptococcus pneumoniae D39

58.766

99.581

0.585
  comA Streptococcus pneumoniae R6

58.766

99.581

0.585
  comA Streptococcus pneumoniae TIGR4

58.626

99.581

0.584
  comA Streptococcus mitis SK321

58.485

99.581

0.582
  comA Streptococcus gordonii str. Challis substr. CH1

57.242

100

0.574
  comA/nlmT Streptococcus mutans UA159

54.735

100

0.549

Multiple sequence alignment