Detailed information NTG0183325

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LLUC109_RS08605
• Genome accession: NZ_CP015907
• Coordinates: 1706509..1707780 (-)
• Length: 423 a.a.
• NCBI ID: WP_324187032.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain UC109
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1704995..1705885	1706509..1707780	flank	624

Gene organization within MGE regions

Location: 1704995..1707780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC109_RS08595 (LLUC109_1658)	-	1705036..1705926 (-)	891	WP_318175638.1	IS982-like element IS982B family transposase	-
LLUC109_RS08600 (LLUC109_02940)	comEC	1706003..1706512 (-)	510	WP_228764033.1	MBL fold metallo-hydrolase	Machinery gene
LLUC109_RS08605 (LLUC109_1659)	comEC	1706509..1707780 (-)	1272	WP_324187032.1	ComEC/Rec2 family competence protein	Machinery gene

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 49044.21 Da
• Isoelectric Point: 9.7194

>NTDB_id=183325 LLUC109_RS08605 WP_324187032.1 1706509..1707780(-) (comEC) [Lactococcus cremoris strain UC109]
MIPILIVFAVFFLLINSLSIRDNENQPKNLSKIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNC
QLSFTGNLEIPETQRNFNGFDDQKYLTSQNIYRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFG
FLSKDFNQMSDIYSSLGIIHLFALSGMQVNFFIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNI
RLTSLDNIAVTTLVLMLISPKFLLTTGGQLTLFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLS
ILLTIIFGFLFDFMLLPLLLCCFLISFLGFLLNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSF
SHKKRRFFLIGFIFLFFSSLKIQ

Nucleotide

• Length: 1272 bp

>NTDB_id=183325 LLUC109_RS08605 WP_324187032.1 1706509..1707780(-) (comEC) [Lactococcus cremoris strain UC109]
ATGATTCCGATATTAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACC
AAAAAATCTCTCAAAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGA
ATGGACAAAAATATCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGT
CAGTTAAGTTTCACAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAAC
TAGTCAAAATATCTATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTT
TAAGGCGAAAGGCAATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGC
TTTTTAAGTAAGGATTTTAATCAGATGAGCGATATTTATAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAAT
GCAAGTAAATTTTTTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTC
AAATTCCATTTTCTATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATT
CGTCTGACTTCTTTGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGG
TGGTCAGCTTACCTTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAG
TGCTGACAGAATCATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCA
ATATTATTAACAATTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATT
TTTGGGATTTTTGCTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATT
ACCCCTTTGTTTTGGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTT
TCTCATAAAAAAAGGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTCATCACTAAAAATCCAATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (157-397)

• Domain of unknown function (DUF4131) (DUF4131) (56-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	96.882	98.582	0.955
comEC/celB	Streptococcus mitis SK321	46.512	91.489	0.426
comEC/celB	Streptococcus mitis NCTC 12261	45.995	91.489	0.421
comEC/celB	Streptococcus pneumoniae TIGR4	45.995	91.489	0.421
comEC/celB	Streptococcus pneumoniae Rx1	45.22	91.489	0.414
comEC/celB	Streptococcus pneumoniae D39	45.22	91.489	0.414
comEC/celB	Streptococcus pneumoniae R6	45.22	91.489	0.414