Detailed information NTG0183083

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LLUC06_RS09980
• Genome accession: NZ_CP015902
• Coordinates: 1997053..1999263 (-)
• Length: 736 a.a.
• NCBI ID: WP_081213664.1
• Uniprot ID: A0A1V0P3Y6
• Organism: Lactococcus lactis subsp. lactis strain UC06
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1992053..2004263

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC06_RS09950 (LLUC06_1938)	atpA	1992095..1993597 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
LLUC06_RS09955 (LLUC06_1939)	-	1993784..1994311 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
LLUC06_RS09960 (LLUC06_1940)	atpF	1994313..1994819 (-)	507	WP_081213662.1	F0F1 ATP synthase subunit B	-
LLUC06_RS09965 (LLUC06_1941)	atpB	1994834..1995547 (-)	714	WP_081213663.1	F0F1 ATP synthase subunit A	-
LLUC06_RS09970 (LLUC06_1942)	-	1995592..1995807 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LLUC06_RS09975 (LLUC06_1943)	-	1995992..1996768 (-)	777	WP_058220836.1	alpha/beta hydrolase family protein	-
LLUC06_RS09980 (LLUC06_1944)	comEC	1997053..1999263 (-)	2211	WP_081213664.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LLUC06_RS09985 (LLUC06_1945)	comEA	1999244..1999891 (-)	648	WP_081213665.1	ComEA family DNA-binding protein	Machinery gene
LLUC06_RS09990 (LLUC06_1946)	-	1999950..2001311 (-)	1362	WP_058220838.1	ABC transporter permease	-
LLUC06_RS09995 (LLUC06_1947)	-	2001308..2002240 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LLUC06_RS10000 (LLUC06_1948)	-	2002345..2002743 (-)	399	WP_081213666.1	hypothetical protein	-
LLUC06_RS10005 (LLUC06_1949)	-	2002847..2003410 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84534.21 Da
• Isoelectric Point: 9.7368

>NTDB_id=183083 LLUC06_RS09980 WP_081213664.1 1997053..1999263(-) (comEC) [Lactococcus lactis subsp. lactis strain UC06]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYTFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHTFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPKESWQKPQSQTNAEKTLIPYLESVGLSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=183083 LLUC06_RS09980 WP_081213664.1 1997053..1999263(-) (comEC) [Lactococcus lactis subsp. lactis strain UC06]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTTAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATACATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCGT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGATTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATACTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCTTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGAAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGATTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

3D structure

• AlphaFold DB: A0A1V0P3Y6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.63	100	0.766
comEC/celB	Streptococcus mitis SK321	44.205	100	0.446
comEC/celB	Streptococcus mitis NCTC 12261	44.07	100	0.444
comEC/celB	Streptococcus pneumoniae TIGR4	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae Rx1	42.934	100	0.433
comEC/celB	Streptococcus pneumoniae D39	42.934	100	0.433
comEC/celB	Streptococcus pneumoniae R6	42.934	100	0.433