Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   A6B47_RS12820 Genome accession   NZ_CP015883
Coordinates   2582557..2583855 (+) Length   432 a.a.
NCBI ID   WP_025187366.1    Uniprot ID   -
Organism   Enterococcus faecalis strain sorialis     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2577557..2588855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6B47_RS12795 (A6B47_12485) - 2577666..2579156 (+) 1491 WP_002378939.1 hypothetical protein -
  A6B47_RS15500 - 2579623..2579772 (-) 150 WP_168354161.1 hypothetical protein -
  A6B47_RS12805 (A6B47_12495) - 2579896..2580108 (-) 213 WP_016633824.1 DUF960 family protein -
  A6B47_RS12810 (A6B47_12500) - 2580405..2581337 (-) 933 WP_002378941.1 hypothetical protein -
  A6B47_RS12815 (A6B47_12505) rlmH 2581677..2582156 (-) 480 WP_002378942.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A6B47_RS12820 (A6B47_12510) htrA 2582557..2583855 (+) 1299 WP_025187366.1 S1C family serine protease Regulator
  A6B47_RS12825 (A6B47_12515) ytpR 2583902..2584522 (-) 621 WP_002368407.1 YtpR family tRNA-binding protein -
  A6B47_RS12830 (A6B47_12520) - 2584733..2585188 (-) 456 WP_002385249.1 universal stress protein -
  A6B47_RS12835 (A6B47_12525) - 2585336..2585650 (-) 315 WP_002355015.1 thioredoxin family protein -
  A6B47_RS12840 (A6B47_12530) pepA 2585662..2586738 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  A6B47_RS12845 (A6B47_12535) - 2587045..2587386 (+) 342 WP_002355012.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44845.98 Da        Isoelectric Point: 4.9968

>NTDB_id=182759 A6B47_RS12820 WP_025187366.1 2582557..2583855(+) (htrA) [Enterococcus faecalis strain sorialis]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKIDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=182759 A6B47_RS12820 WP_025187366.1 2582557..2583855(+) (htrA) [Enterococcus faecalis strain sorialis]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTGGATAAAGCACAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTATACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCGCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATTAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAATTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(9-416)

PDZ domain (PDZ_2)

(319-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.415

94.907

0.507
  htrA Streptococcus mutans UA159

58.904

84.491

0.498
  htrA Streptococcus mitis NCTC 12261

54.865

85.648

0.47
  htrA Streptococcus pneumoniae TIGR4

55.524

81.713

0.454
  htrA Streptococcus pneumoniae Rx1

55.524

81.713

0.454
  htrA Streptococcus pneumoniae D39

55.524

81.713

0.454
  htrA Streptococcus pneumoniae R6

55.524

81.713

0.454

Multiple sequence alignment