Detailed information NTG0180794

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BZY74_RS16225
• Genome accession: NZ_CP019558
• Coordinates: 3178521..3180797 (+)
• Length: 758 a.a.
• NCBI ID: WP_000934053.1
• Uniprot ID: -
• Organism: Escherichia coli strain KSC207
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3173521..3185797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZY74_RS16205 (BZY74_16415)	macA	3174492..3175607 (+)	1116	WP_000746460.1	macrolide transporter subunit MacA	-
BZY74_RS16210 (BZY74_16420)	macB	3175604..3177550 (+)	1947	WP_000188194.1	macrolide ABC transporter ATP-binding protein/permease MacB	-
BZY74_RS16215 (BZY74_16425)	cspD	3177623..3177847 (-)	225	WP_000410785.1	cold shock-like protein CspD	-
BZY74_RS26365	yljB	3177997..3178071 (+)	75	WP_001406719.1	protein YljB	-
BZY74_RS16220 (BZY74_16430)	clpS	3178170..3178490 (+)	321	WP_000520781.1	ATP-dependent Clp protease adapter ClpS	-
BZY74_RS16225 (BZY74_16435)	clpC	3178521..3180797 (+)	2277	WP_000934053.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
BZY74_RS16235 (BZY74_16450)	infA	3181481..3181699 (-)	219	WP_001040187.1	translation initiation factor IF-1	-
BZY74_RS16245 (BZY74_16460)	aat	3181984..3182688 (-)	705	WP_032296614.1	leucyl/phenylalanyl-tRNA--protein transferase	-
BZY74_RS16250 (BZY74_16465)	cydC	3182730..3184451 (-)	1722	WP_001202189.1	heme ABC transporter ATP-binding protein/permease CydC	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84224.96 Da
• Isoelectric Point: 6.2512

>NTDB_id=180794 BZY74_RS16225 WP_000934053.1 3178521..3180797(+) (clpC) [Escherichia coli strain KSC207]
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQP
TLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVM
ADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPMLSSGKIRVIG
STTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAID
VIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAG
LGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAV
LLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEF
RNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANEL
LFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH

Nucleotide

• Length: 2277 bp

>NTDB_id=180794 BZY74_RS16225 WP_000934053.1 3178521..3180797(+) (clpC) [Escherichia coli strain KSC207]
ATGCTCAATCAAGAACTGGAACTCAGTTTAAATATGGCTTTCGCCAGAGCGCGCGAGCACCGTCATGAGTTTATGACCGT
CGAGCACTTGTTACTGGCGCTGCTCAGTAACCCATCTGCCCGGGAGGCGCTGGAAGCGTGTTCTGTGGATTTGGTTGCGC
TCCGTCAGGAACTGGAAGCCTTTATTGAACAAACCACACCCGTTCTGCCTGCCAGTGAAGAGGAGCGCGACACACAGCCG
ACGCTGAGTTTTCAGCGTGTACTGCAACGTGCGGTCTTCCATGTCCAGTCCTCCGGTCGCAATGAGGTTACCGGTGCAAA
CGTTCTGGTCGCTATCTTTAGCGAACAGGAGTCGCAGGCGGCATATCTGTTGCGTAAACATGAAGTCAGCCGTCTCGATG
TGGTGAATTTTATCTCTCATGGCACGCGTAAAGACGAGCCGACACAGTCTTCTGATCCTGGCAGCCAGCCAAACAGCGAA
GAACAAGCTGGTGGGGAGGAACGTATGGAGAATTTCACGACGAACCTGAATCAGCTTGCGCGCGTGGGCGGAATCGACCC
ACTGATTGGTCGTGAGAAGGAGCTGGAGCGTGCTATTCAGGTTCTCTGCCGTCGCCGTAAAAACAACCCGCTGCTGGTGG
GGGAATCTGGTGTCGGTAAAACCGCGATTGCAGAAGGTCTTGCCTGGCGAATTGTTCAGGGCGATGTGCCGGAAGTGATG
GCTGACTGTACGATTTACTCTCTCGATATCGGTTCTCTGTTAGCGGGCACAAAATATCGCGGCGACTTTGAAAAACGTTT
TAAAGCGTTGCTCAAGCAGCTGGAGCAGGACACTAACAGCATCCTGTTTATTGATGAGATCCACACCATTATCGGTGCGG
GGGCAGCGTCTGGTGGTCAGGTCGATGCGGCTAACCTAATCAAACCGATGCTCTCCAGCGGTAAAATTCGCGTAATTGGT
TCGACAACCTATCAGGAGTTCAGCAACATTTTCGAGAAAGACCGTGCTCTGGCGCGTCGCTTCCAGAAAATTGATATTAC
TGAACCGTCAATCGAAGAAACTGTTCAAATTATCAATGGCCTGAAACCGAAGTATGAAGCGCACCACGACGTGCGTTATA
CCGCAAAAGCGGTGCGTGCGGCGGTAGAGCTGGCGGTGAAATACATCAATGATCGTCATCTGCCGGATAAAGCGATTGAT
GTTATCGACGAAGCGGGCGCTCGCGCACGCCTGATGCCGGTAAGCAAACGCAAGAAAACCGTTAATGTGGCGGATATTGA
GTCCGTGGTGGCCCGTATTGCACGCATTCCAGAGAAGAGTGTTTCTCAGAGTGACCGCGATACCCTGAAAAACCTCGGCG
ATCGCCTGAAAATGCTGGTCTTCGGTCAGGATAAAGCCATTGAGGCGCTGACTGAAGCCATTAAGATGGCGCGTGCAGGT
TTAGGTCACGAACATAAACCGGTCGGTTCGTTCCTGTTTGCCGGTCCTACCGGGGTCGGGAAAACAGAGGTGACGGTACA
GCTTTCGAAAGCGTTGGGCATTGAGCTTCTGCGCTTTGATATGTCCGAGTATATGGAACGCCATACCGTCAGCCGTCTGA
TTGGTGCGCCTCCGGGATACGTTGGTTTTGATCAGGGCGGTTTGCTGACCGATGCGGTAATCAAGCATCCACATGCGGTG
CTGCTGCTGGACGAAATCGAGAAAGCGCATCCGGACGTGTTCAATATTCTGTTGCAGGTGATGGACAACGGTACGCTGAC
CGATAACAACGGACGCAAAGCGGACTTCCGTAACGTGGTGCTGGTGATGACCACCAACGCCGGGGTACGGGAAACTGAGC
GCAAATCCATTGGTCTTATCCACCAGGATAACAGCACCGATGCGATGGAAGAGATCAAGAAGATCTTTACACCGGAATTC
CGTAACCGTCTCGACAACATTATCTGGTTTGATCATTTGTCAACCGACGTGATTCATCAGGTGGTGGATAAATTCATCGT
CGAGTTGCAGGTTCAGCTGGATCAGAAAGGTGTTTCTCTGGAAGTGAGCCAGGAAGCGCGTAACTGGCTGGCCGAGAAAG
GTTACGACCGGGCAATGGGCGCACGTCCGATGGCGCGTGTCATCCAGGACAACCTGAAAAAACCGCTCGCCAACGAACTG
CTGTTTGGTTCGCTGGTGGACGGCGGTCAGGTCACCGTAGCGCTGGATAAAGAGAAAAATGAGCTGACTTACGGATTCCA
GAGTGCACAAAAGCACAAGGCGGAAGCAGCGCATTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (486-647)

• AAA lid domain (AAA_lid_9) (350-452)

• ATPase family associated with various cellular activities (AAA) (AAA) (211-342)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-733)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.868	100	0.408
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.346	96.042	0.397
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	35.46	100	0.381
clpC	Streptococcus thermophilus LMD-9	42.37	89.05	0.377
clpC	Streptococcus thermophilus LMG 18311	42.222	89.05	0.376
clpC	Streptococcus mutans UA159	39.407	93.404	0.368