Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A6M16_RS08870 Genome accession   NZ_CP015557
Coordinates   1793999..1794721 (-) Length   240 a.a.
NCBI ID   WP_024395369.1    Uniprot ID   -
Organism   Streptococcus suis strain DN13     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1788999..1799721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS08850 (A6M16_08855) - 1789071..1790294 (-) 1224 WP_063725367.1 cysteine desulfurase -
  A6M16_RS08855 (A6M16_08860) sufD 1790298..1791560 (-) 1263 WP_024389689.1 Fe-S cluster assembly protein SufD -
  A6M16_RS08860 (A6M16_08865) sufC 1791577..1792350 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  A6M16_RS08865 (A6M16_08870) - 1792830..1794002 (-) 1173 WP_014736360.1 glycosyltransferase family 4 protein -
  A6M16_RS08870 (A6M16_08875) mecA 1793999..1794721 (-) 723 WP_024395369.1 adaptor protein MecA Regulator
  A6M16_RS08875 (A6M16_08880) - 1794849..1795685 (-) 837 WP_024395368.1 undecaprenyl-diphosphate phosphatase -
  A6M16_RS08880 (A6M16_08885) - 1795812..1797377 (+) 1566 WP_024395367.1 ABC transporter substrate-binding protein/permease -
  A6M16_RS08885 (A6M16_08890) - 1797370..1798113 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  A6M16_RS08890 (A6M16_08895) - 1798241..1798450 (-) 210 WP_009910800.1 hypothetical protein -
  A6M16_RS08895 (A6M16_08900) - 1798536..1799438 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27958.54 Da        Isoelectric Point: 4.0987

>NTDB_id=180696 A6M16_RS08870 WP_024395369.1 1793999..1794721(-) (mecA) [Streptococcus suis strain DN13]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSGPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIKDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=180696 A6M16_RS08870 WP_024395369.1 1793999..1794721(-) (mecA) [Streptococcus suis strain DN13]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGGACCGGATGCAACAGCCGTTCGCCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAAAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCGGTAGAAGAATCGGAATTATATAAAATGGATGGTCATTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCTAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.479

99.167

0.471
  mecA Streptococcus thermophilus LMG 18311

47.059

99.167

0.467

Multiple sequence alignment