Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   A6M16_RS00345 Genome accession   NZ_CP015557
Coordinates   57003..57902 (+) Length   299 a.a.
NCBI ID   WP_015646238.1    Uniprot ID   -
Organism   Streptococcus suis strain DN13     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52003..62902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS00325 (A6M16_00325) - 52296..54008 (+) 1713 WP_063725142.1 ABC transporter ATP-binding protein -
  A6M16_RS11030 - 54109..54282 (+) 174 WP_014637276.1 hypothetical protein -
  A6M16_RS00330 (A6M16_00330) ruvB 54526..55527 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  A6M16_RS00335 (A6M16_00335) - 55527..56273 (+) 747 WP_024395313.1 GNAT family N-acetyltransferase -
  A6M16_RS00340 (A6M16_00340) - 56275..56898 (+) 624 WP_024395312.1 HAD-IA family hydrolase -
  A6M16_RS00345 (A6M16_00345) comR 57003..57902 (+) 900 WP_015646238.1 helix-turn-helix domain-containing protein Regulator
  A6M16_RS00350 (A6M16_00350) - 58109..59329 (+) 1221 WP_024395311.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  A6M16_RS00360 (A6M16_00360) - 59520..61043 (+) 1524 WP_063725143.1 hypothetical protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35175.03 Da        Isoelectric Point: 4.5398

>NTDB_id=180655 A6M16_RS00345 WP_015646238.1 57003..57902(+) (comR) [Streptococcus suis strain DN13]
MNDKEFGQRVRQLRENASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVNKDRGEAEKHYLDAMLFAKLIENRELEQKIEEDWKVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=180655 A6M16_RS00345 WP_015646238.1 57003..57902(+) (comR) [Streptococcus suis strain DN13]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAAACGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAACTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTACCCGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTCCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTGTCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTCAACG
CAAGATTTTCAGAAAAAGCCAATTGTCAGTGTGTTGAAATGGAAGTATGCACTTTTTGTAAATAAGGATAGAGGTGAGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGCAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

92.977

100

0.93
  comR Streptococcus suis 05ZYH33

92.977

100

0.93
  comR Streptococcus suis D9

59.801

100

0.602
  comR Streptococcus mutans UA159

45.151

100

0.452
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.801

97.324

0.368
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368

Multiple sequence alignment