Detailed information NTG0179241

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: A4V07_RS08415
• Genome accession: NZ_CP015408
• Coordinates: 1718166..1720307 (+)
• Length: 713 a.a.
• NCBI ID: WP_065533508.1
• Uniprot ID: -
• Organism: Limosilactobacillus reuteri strain I49
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1713166..1725307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4V07_RS08400 (A4V07_08305)	-	1713394..1714446 (+)	1053	WP_231117236.1	GHKL domain-containing protein	-
A4V07_RS08405 (A4V07_08310)	-	1714454..1715221 (+)	768	WP_065533506.1	LytR/AlgR family response regulator transcription factor	-
A4V07_RS08410 (A4V07_08315)	ltrA	1715721..1717103 (+)	1383	WP_065533507.1	group II intron reverse transcriptase/maturase	-
A4V07_RS09830	-	1717360..1717527 (+)	168	WP_153706895.1	hypothetical protein	-
A4V07_RS09960	-	1717529..1717687 (+)	159	WP_191980603.1	hypothetical protein	-
A4V07_RS09965	-	1717729..1717890 (+)	162	WP_162859766.1	hypothetical protein	-
A4V07_RS08415 (A4V07_08320)	comA	1718166..1720307 (+)	2142	WP_065533508.1	peptide cleavage/export ABC transporter	Regulator
A4V07_RS08420 (A4V07_08325)	-	1720349..1720534 (-)	186	WP_003665308.1	hypothetical protein	-
A4V07_RS08425 (A4V07_08330)	-	1720814..1721242 (-)	429	WP_035156131.1	OsmC family protein	-
A4V07_RS08430 (A4V07_08335)	-	1721311..1722306 (-)	996	WP_065533509.1	D-2-hydroxyacid dehydrogenase	-
A4V07_RS08435 (A4V07_08340)	-	1722308..1723495 (-)	1188	WP_065533510.1	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	-
A4V07_RS08440 (A4V07_08345)	-	1724000..1724221 (+)	222	WP_065533511.1	hypothetical protein	-

Sequence

Protein

• Length: 713 a.a.
• Molecular weight: 80569.68 Da
• Isoelectric Point: 7.1576

>NTDB_id=179241 A4V07_RS08415 WP_065533508.1 1718166..1720307(+) (comA) [Limosilactobacillus reuteri strain I49]
MKINYPHYVAQVDEADCGVAALAMILHNFGSVYPIAKLRDLARTTKQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEI
TYPLIAHVIKDDLLHYCVVFKADQDYIYVADPDPATKVQKMTRDEFGRLWSGVSLLFSPAKEYTPQKEPLAGLTTMFQQL
TNYKKDISGIIIAALLITLISIVGSYYLQLIIDRFIPSKSINGLAILAGSLLVVYVFNSLFNYLRDVILTRLDQKLTSQI
SLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSSTIISMFLDVGVMVIIGIVLSLYDQSLFLTTISTIPIYVII
IYAFNKRFAKLDQEQMESNAQLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQYG
LVTIILFQGAILVIQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLNEVLQVDTEKSDTNSQDQTDLIG
PISIQHVDYSYEYSRPILQDIKLQIGCNDKLAIVGLSGSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHY
LPQSPQLFSGTIKDNLLMGLDREVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALLTSARV
LIFDESTSSLDPITEKRIVENLLSIKDRTMIFIAHRLSIAKKVNKVVVMRDGKIIEQGTHQELLNHHQEYYNL

Nucleotide

• Length: 2142 bp

>NTDB_id=179241 A4V07_RS08415 WP_065533508.1 1718166..1720307(+) (comA) [Limosilactobacillus reuteri strain I49]
ATGAAAATCAATTATCCTCATTATGTAGCTCAAGTTGATGAAGCAGATTGTGGAGTCGCCGCGTTAGCAATGATTTTGCA
CAATTTTGGGTCTGTTTACCCAATCGCAAAATTACGGGACTTAGCACGGACGACTAAGCAAGGAACTACCGCCTTAGGAC
TTGTAAAAGCAGCGAAGCATCTTGGATTAGACGTTATACCCATTCAAGCAGATATATCATTGTTTGATGATCCTGAAATT
ACTTACCCGTTGATCGCGCATGTGATTAAGGATGATTTACTTCATTACTGTGTTGTCTTTAAGGCTGATCAAGATTACAT
CTATGTAGCTGATCCAGATCCTGCTACGAAAGTACAAAAAATGACGCGGGATGAATTTGGTCGTTTATGGTCAGGTGTAA
GTTTACTTTTTTCGCCTGCTAAGGAGTATACACCGCAAAAAGAACCTTTAGCTGGATTAACGACGATGTTTCAACAATTA
ACTAATTATAAAAAAGATATATCAGGAATTATCATTGCGGCATTATTAATTACCCTCATCAGCATCGTCGGTTCATACTA
TCTCCAATTAATTATTGATCGGTTTATTCCCTCGAAAAGTATTAATGGCTTAGCGATTCTTGCTGGTAGTTTATTAGTAG
TTTATGTGTTTAATTCTCTTTTTAATTATCTGCGAGATGTTATCTTGACTAGGCTGGATCAAAAACTAACGTCACAAATA
AGTCTTAGATATATTCACCATGTTTATCGTTTACCAATGAGATTTTTCTCCACAAGAAAAACGGGGGAAATAACTTCGCG
GTTTAATGACATTAATAAGATTATTGATGCTTTATCAAGCACTATTATTTCAATGTTCTTAGATGTTGGCGTGATGGTGA
TTATTGGCATTGTTCTTTCTTTGTATGATCAGTCATTATTTTTAACTACAATTAGTACCATTCCGATTTATGTCATTATC
ATTTATGCCTTTAATAAGCGCTTTGCTAAACTTGATCAGGAACAGATGGAAAGTAATGCTCAATTAAGTTCTGCCATTAT
TGAGGATTTAAAAGGCGTAGAAACGTTGAAAGTGCTGCAACTTGAAAATATCCGTTATAAAAATGTTGAAAAGCAATTTG
CGGATTTCTTACGAAAGAATCTAACATATGTTAAAACTAAATCTTTTCAGGATGCAATTAAAATGTGGATTCAATACGGT
TTAGTAACAATCATTCTTTTTCAAGGAGCAATTTTGGTAATTCAGGACCGATTAAGTATTGGGACATTAATGGCCTTTAA
TGCATTATTAGCCTTTTTTGTCAGTCCATTACAAAACATTATTAATCTTCAACCTAAACTCCAAGAAGCTAAAGTAGCGA
ATAATCGATTGAATGAAGTGCTGCAAGTTGATACCGAAAAGTCAGATACGAATTCTCAGGATCAAACAGATTTAATAGGG
CCGATAAGCATTCAACATGTTGACTATTCATATGAATATAGTCGTCCAATTTTACAAGATATCAAGCTTCAAATTGGTTG
TAATGATAAACTGGCAATTGTAGGATTGAGCGGTTCTGGTAAATCGACCTTGGCAAAGTTGTTAGTTGGCTTTTATTTAC
CTACTCAAGGGCAGATAGAATTTAATCAGCATAAAACAACAGAGATTAATCTTTGCGATATTAGACAATATGTGCATTAC
TTACCCCAATCGCCACAATTATTTTCGGGAACAATCAAAGATAACTTGCTAATGGGATTAGACCGTGAAGTATCTGCTGA
AGAAATCGATAATGCATGTAAATTGGCGTTAATCTATAATGATATTCAAGAGATGCCCTTAAAATATGAAACAAAACTAG
ATGAAGAAGCAACCGCATTATCTGGTGGTCAAAAACAACGCTTGACGATTGCACGAGCACTCCTAACTTCTGCGCGTGTT
TTAATTTTCGATGAATCAACAAGTAGCTTAGATCCAATTACTGAAAAAAGAATCGTTGAAAATTTGCTTAGTATTAAAGA
CCGCACAATGATTTTTATTGCCCACCGCCTTTCAATTGCTAAAAAGGTCAATAAAGTGGTAGTAATGCGCGACGGAAAAA
TCATTGAACAGGGTACTCACCAGGAACTTTTGAATCATCATCAAGAATACTATAATTTGTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-648)

• Peptidase C39 family (Peptidase_C39) (7-141)

• ABC transporter transmembrane region (ABC_membrane) (170-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	48.531	100	0.487
comA	Streptococcus pneumoniae TIGR4	48.252	100	0.484
comA	Streptococcus pneumoniae Rx1	48.252	100	0.484
comA	Streptococcus pneumoniae D39	48.252	100	0.484
comA	Streptococcus pneumoniae R6	48.252	100	0.484
comA	Streptococcus mitis SK321	47.972	100	0.481
comA	Streptococcus gordonii str. Challis substr. CH1	46.713	100	0.468
comA/nlmT	Streptococcus mutans UA159	46.835	99.719	0.467