Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   V471_RS05600 Genome accession   NZ_CP015283
Coordinates   1089851..1091731 (+) Length   626 a.a.
NCBI ID   WP_002886860.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1084851..1096731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS05585 (V471_05505) fmt 1086823..1087758 (+) 936 WP_070579772.1 methionyl-tRNA formyltransferase -
  V471_RS05590 (V471_05510) rsmB 1087748..1089070 (+) 1323 WP_002886858.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V471_RS05595 (V471_05515) - 1089114..1089851 (+) 738 WP_002886859.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  V471_RS05600 (V471_05520) stkP/pknB 1089851..1091731 (+) 1881 WP_002886860.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V471_RS05605 (V471_05525) - 1091877..1092635 (+) 759 WP_002886861.1 potassium channel family protein -
  V471_RS05610 (V471_05530) liaF 1092799..1093497 (+) 699 WP_084871195.1 cell wall-active antibiotics response protein LiaF -
  V471_RS05615 (V471_05535) - 1093494..1094504 (+) 1011 WP_045768527.1 sensor histidine kinase -
  V471_RS05620 (V471_05540) - 1094494..1095138 (+) 645 WP_002884791.1 response regulator transcription factor -
  V471_RS05635 (V471_05555) rimM 1095835..1096353 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 68145.84 Da        Isoelectric Point: 7.6981

>NTDB_id=178311 V471_RS05600 WP_002886860.1 1089851..1091731(+) (stkP/pknB) [Streptococcus salivarius strain ATCC 25975]
MIQVGKLFAGRYRILKAIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEILSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGRIPYDGDSAVTIALQHFQKPLPSILAENHNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLYPSHSRDAKVVFDDMTDTKTLPKVTPVPSVSSEKKATAKSSESKQAV
SKQPRKNSTLAKNKKKKKKKSFFSTSLKVFLGLVFIGIIIFAYLVFTNPDSTQVPNVVGQELSTAQTKIEGAGFKVGEVK
EVEDDSVDTGKVVKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEE
GEILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSST
EVLYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTESTSSSTETPTEATHTDQQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=178311 V471_RS05600 WP_002886860.1 1089851..1091731(+) (stkP/pknB) [Streptococcus salivarius strain ATCC 25975]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAAGCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATCTTGGATAATGAGAAAGTGGCCATTAAGGTGCTTCGTACTAATTATCAAACCGATCAGGTAG
CTGTGGCACGTTTCCAGCGTGAAGCACGTGCCATGGCAGAACTCAGTCATCCCAATATCGTTGCAATCCGAGACATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTACGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCACC
ACTTTCTAACCAAGATGTTGTGCGTATTATGGGAGAGATTCTTTCTGCCATGACTCTTGCCCATCAAAAGGGTATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTAGGGCCAAAGTTACAGACTTCGGGATTGCGGTTGCC
TTTGCAGAGACTAGTTTGACTCAAACCAATTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCGCGTGGATC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGTATCATGCTCTTTGAAATGTTGACAGGGCGTATTCCATATGATG
GTGATAGTGCAGTTACCATCGCTCTTCAGCATTTCCAAAAACCATTACCATCAATCTTGGCTGAGAATCATAATGTTCCT
CAGGCATTGGAAAATGTGGTTATTCGAGCGACAGCTAAAAAGCTTGAAAATCGTTATAACAGTACTTTGGAAATGAGCCG
AGATTTAGTAACTAGCTTATATCCTAGCCATAGCCGTGATGCGAAGGTAGTCTTTGATGACATGACGGATACTAAGACTT
TGCCTAAGGTTACTCCAGTTCCGTCAGTAAGCTCTGAGAAAAAGGCAACTGCCAAGTCATCAGAGTCAAAACAAGCTGTA
AGTAAGCAACCAAGGAAAAATTCAACACTAGCTAAGAATAAAAAGAAGAAAAAAAAGAAAAGCTTTTTCTCGACATCACT
CAAGGTATTCCTGGGGTTGGTCTTTATCGGGATTATCATTTTTGCCTATTTGGTATTTACCAACCCTGATAGTACTCAGG
TGCCTAACGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGTGAAGTTAAG
GAAGTGGAAGATGACTCTGTCGATACAGGCAAGGTCGTAAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATC
AAGCATTGATATCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAATTATAAGGATGCCA
TTGAGGATTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAG
GGAGAAATCCTATCTCAAAGTCCAGGTAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGT
GGCAACTCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGA
GTATCTCAAGTAGTAGCATCGAGTATCATGACTATAATACTGGTGCTAAGTTAGACAAGGATAAGGTTCCTAGCAGTACA
GAGGTCCTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAG
TTCAAGCCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGAAAGCACAAGCTCTAGTA
CTGAAACACCGACAGAGGCTACTCACACAGACCAACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(443-507)

PASTA domain (PASTA)

(513-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

93.142

100

0.933
  pknB Streptococcus mutans UA159

65.993

86.901

0.573
  stkP Streptococcus pneumoniae TIGR4

51.286

93.131

0.478
  stkP Streptococcus pneumoniae D39

51.115

93.131

0.476
  stkP Streptococcus pneumoniae R6

51.115

93.131

0.476
  stkP Streptococcus pneumoniae Rx1

50.943

93.131

0.474

Multiple sequence alignment