Detailed information NTG0178309

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: V471_RS05530
• Genome accession: NZ_CP015283
• Coordinates: 1075938..1077023 (+)
• Length: 361 a.a.
• NCBI ID: WP_037601740.1
• Uniprot ID: A0A074IQF0
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1070938..1082023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS05515 (V471_05435)	amiA	1071005..1072975 (+)	1971	WP_014632817.1	peptide ABC transporter substrate-binding protein	Regulator
V471_RS05520 (V471_05440)	amiC	1073509..1075002 (+)	1494	WP_014632819.1	ABC transporter permease	Regulator
V471_RS05525 (V471_05445)	amiD	1075002..1075928 (+)	927	WP_002886846.1	oligopeptide ABC transporter permease OppC	Regulator
V471_RS05530 (V471_05450)	amiE	1075938..1077023 (+)	1086	WP_037601740.1	ABC transporter ATP-binding protein	Regulator
V471_RS05535 (V471_05455)	amiF	1077016..1077945 (+)	930	WP_014634820.1	ATP-binding cassette domain-containing protein	Regulator
V471_RS05540 (V471_05460)	-	1077995..1078780 (-)	786	WP_041826692.1	hypothetical protein	-
V471_RS05545 (V471_05465)	-	1078792..1079490 (-)	699	WP_084871193.1	ABC transporter ATP-binding protein	-
V471_RS05550 (V471_05470)	-	1079495..1079872 (-)	378	WP_002884206.1	GntR family transcriptional regulator	-
V471_RS05555 (V471_05475)	-	1080054..1080848 (+)	795	WP_084871194.1	HAD-IIB family hydrolase	-
V471_RS05560 (V471_05480)	-	1080841..1081659 (+)	819	WP_070579768.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39981.66 Da
• Isoelectric Point: 4.6135

>NTDB_id=178309 V471_RS05530 WP_037601740.1 1075938..1077023(+) (amiE) [Streptococcus salivarius strain ATCC 25975]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGQDL
TKLKSHQDWAAIRGAKIATIFQDPMTSLDPIKTIGSQIVEVIVKHQGKSAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDKGELFSIPGTPPSLYTPVVGDAFALRSDYAMQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVEKPEVIQNLHEKIRTNMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=178309 V471_RS05530 WP_037601740.1 1075938..1077023(+) (amiE) [Streptococcus salivarius strain ATCC 25975]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGAGTTTCCCTTGATTTGGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGTAAATCAGTTT
TGACCAAGACCTTCACAGGGATGCTTGAAGAAAATGGTCGTGTCGCTAGTGGTTCTATTGATTATCGTGGCCAAGATTTG
ACCAAGCTTAAGAGTCACCAAGATTGGGCAGCAATTCGTGGAGCTAAGATTGCAACTATCTTCCAAGATCCTATGACCAG
TCTTGACCCAATTAAGACTATCGGTAGCCAAATTGTTGAAGTCATTGTCAAACACCAAGGAAAATCAGCCAAAGAAGCTA
AAAAAATGGCCATTGATTACATGGACAAGGTTGGTATTCCTGATGCTGAAAAACGTTTCAACGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTCATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAGCCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTTTTGAAATCACTCAAAGAGGAGTATGGTTTCTCAGTGA
TTTTCATTACCCATGACCTTGGTGTGGTAGCAAGTATCGCTGACAAGGTTGCTGTTATGTATGCTGGTGAAATCATCGAG
TACGCAACGGTTGAGGAAATTTTCTATGAGCCTTGTCACCCATACACTTGGAGCTTGCTTTCAAGCTTGCCACAGTTGGC
TGACGATAAGGGTGAGCTTTTCTCTATTCCAGGGACACCACCATCACTTTATACACCAGTTGTTGGAGATGCCTTTGCCT
TGCGTTCAGACTATGCCATGCAAATTGACTTCGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCACCAAAAGTTGAAAAACCTGAGGTTATCCAAAATCTACATGAAAAAATCCGTACTAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A074IQF0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	99.169	100	0.992
amiE	Streptococcus thermophilus LMG 18311	96.676	100	0.967
amiE	Streptococcus thermophilus LMD-9	96.676	100	0.967
oppD	Streptococcus mutans UA159	54.728	96.676	0.529