Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V471_RS04315 Genome accession   NZ_CP015283
Coordinates   821525..822214 (+) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 816525..827214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS11380 - 817464..817586 (+) 123 Protein_782 energy-coupling factor transporter transmembrane protein EcfT -
  V471_RS04295 (V471_04235) - 817676..818347 (-) 672 WP_002886585.1 potassium channel family protein -
  V471_RS04300 (V471_04240) - 818387..819751 (-) 1365 WP_080976121.1 TrkH family potassium uptake protein -
  V471_RS04305 (V471_04245) rsmG 819821..820534 (-) 714 WP_049529060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V471_RS04310 (V471_04250) - 820833..821369 (+) 537 WP_049529058.1 DUF177 domain-containing protein -
  V471_RS04315 (V471_04255) covR 821525..822214 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  V471_RS04320 (V471_04260) covS 822211..823740 (+) 1530 WP_002886591.1 HAMP domain-containing histidine kinase Regulator
  V471_RS04325 (V471_04265) nrdR 823862..824341 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  V471_RS04330 (V471_04270) - 824338..825513 (+) 1176 WP_049529055.1 DnaD domain protein -
  V471_RS04335 (V471_04275) dnaI 825517..826419 (+) 903 WP_013990064.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=178295 V471_RS04315 WP_002886589.1 821525..822214(+) (covR) [Streptococcus salivarius strain ATCC 25975]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=178295 V471_RS04315 WP_002886589.1 821525..822214(+) (covR) [Streptococcus salivarius strain ATCC 25975]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACG
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTATTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment