Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V471_RS04320 Genome accession   NZ_CP015283
Coordinates   822211..823740 (+) Length   509 a.a.
NCBI ID   WP_002886591.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 817211..828740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS11380 - 817464..817586 (+) 123 Protein_782 energy-coupling factor transporter transmembrane protein EcfT -
  V471_RS04295 (V471_04235) - 817676..818347 (-) 672 WP_002886585.1 potassium channel family protein -
  V471_RS04300 (V471_04240) - 818387..819751 (-) 1365 WP_080976121.1 TrkH family potassium uptake protein -
  V471_RS04305 (V471_04245) rsmG 819821..820534 (-) 714 WP_049529060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V471_RS04310 (V471_04250) - 820833..821369 (+) 537 WP_049529058.1 DUF177 domain-containing protein -
  V471_RS04315 (V471_04255) covR 821525..822214 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  V471_RS04320 (V471_04260) covS 822211..823740 (+) 1530 WP_002886591.1 HAMP domain-containing histidine kinase Regulator
  V471_RS04325 (V471_04265) nrdR 823862..824341 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  V471_RS04330 (V471_04270) - 824338..825513 (+) 1176 WP_049529055.1 DnaD domain protein -
  V471_RS04335 (V471_04275) dnaI 825517..826419 (+) 903 WP_013990064.1 primosomal protein DnaI -
  V471_RS04340 (V471_04280) der 826524..827834 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V471_RS04345 (V471_04285) - 827898..828527 (+) 630 WP_084871135.1 ribonuclease P -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58137.57 Da        Isoelectric Point: 5.3949

>NTDB_id=178296 V471_RS04320 WP_002886591.1 822211..823740(+) (covS) [Streptococcus salivarius strain ATCC 25975]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADRETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=178296 V471_RS04320 WP_002886591.1 822211..823740(+) (covS) [Streptococcus salivarius strain ATCC 25975]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGATTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCGATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCGCGTAACC
GTACAACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATCGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.625

100

0.986

Multiple sequence alignment