Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   V471_RS00455 Genome accession   NZ_CP015283
Coordinates   93122..93820 (-) Length   232 a.a.
NCBI ID   WP_084870986.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 88122..98820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS00440 (V471_00445) - 88933..89478 (-) 546 WP_084870984.1 GNAT family N-acetyltransferase -
  V471_RS00445 (V471_00450) - 89544..90806 (-) 1263 WP_013991032.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  V471_RS00450 (V471_00455) comEC/celB 90892..93132 (-) 2241 WP_084870985.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V471_RS00455 (V471_00460) comEA 93122..93820 (-) 699 WP_084870986.1 helix-hairpin-helix domain-containing protein Machinery gene
  V471_RS00460 (V471_00465) - 93929..94684 (-) 756 WP_084870987.1 lysophospholipid acyltransferase family protein -
  V471_RS00465 (V471_00470) - 94814..95749 (+) 936 WP_084871503.1 polysaccharide deacetylase family protein -
  V471_RS00470 (V471_00475) - 95799..96563 (+) 765 WP_037599202.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  V471_RS00475 (V471_00480) - 96567..96836 (+) 270 WP_084870988.1 GIY-YIG nuclease family protein -
  V471_RS00480 (V471_00485) - 96928..97314 (-) 387 WP_002886743.1 IS110 family transposase -
  V471_RS00485 (V471_00490) - 97334..98095 (-) 762 WP_002886742.1 IS110 family transposase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24468.38 Da        Isoelectric Point: 4.6300

>NTDB_id=178261 V471_RS00455 WP_084870986.1 93122..93820(-) (comEA) [Streptococcus salivarius strain ATCC 25975]
MKEKILAYVKDNCLFVSVIAVLMVIFCFFLWMTYGAGNSMEAETSYTDVTALSTSSSSKQSSQSLSEASSQSKTEGSEKD
KLKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVIYVATKDENLSVLGQSGTGQVSDK
GGQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 699 bp        

>NTDB_id=178261 V471_RS00455 WP_084870986.1 93122..93820(-) (comEA) [Streptococcus salivarius strain ATCC 25975]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATTGTCTGTTTGTGAGTGTTATTGCTGTACTGATGGTGATTTTTTG
CTTCTTCCTATGGATGACTTATGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCCTCCTCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGAT
AAGTTAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGCTAATCCAGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTGAC
TGATGCCATCAAAGCTGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAATTTAGCCGCAAGTCTGTCGGACG
AAGAGGTTATCTATGTGGCAACTAAGGATGAAAACCTCTCTGTTCTTGGTCAATCAGGAACTGGTCAGGTCTCTGACAAA
GGAGGGCAAACTAGTGCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGGAGTTGCAAACTATTTCTGGAAT
TGGAGCTAAGCGGGCAGAGGATATCATTGCCTATCGTGAAAGTCATGGAGGCTTTCAATCCGTAGATGACTTGAAAAATG
TCTCAGGAATTGGTGATAAAACTTTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(169-229)

SLBB domain (SLBB)

(86-139)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

89.224

100

0.892
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

40.435

99.138

0.401
  comEA/celA/cilE Streptococcus mitis SK321

40

99.138

0.397

Multiple sequence alignment