Detailed information NTG0178260

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V471_RS00450
• Genome accession: NZ_CP015283
• Coordinates: 90892..93132 (-)
• Length: 746 a.a.
• NCBI ID: WP_084870985.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 85892..98132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS00430 (V471_00435)	-	86760..87620 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
V471_RS00435 (V471_00440)	spxR	87660..88940 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V471_RS00440 (V471_00445)	-	88933..89478 (-)	546	WP_084870984.1	GNAT family N-acetyltransferase	-
V471_RS00445 (V471_00450)	-	89544..90806 (-)	1263	WP_013991032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V471_RS00450 (V471_00455)	comEC/celB	90892..93132 (-)	2241	WP_084870985.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V471_RS00455 (V471_00460)	comEA	93122..93820 (-)	699	WP_084870986.1	helix-hairpin-helix domain-containing protein	Machinery gene
V471_RS00460 (V471_00465)	-	93929..94684 (-)	756	WP_084870987.1	lysophospholipid acyltransferase family protein	-
V471_RS00465 (V471_00470)	-	94814..95749 (+)	936	WP_084871503.1	polysaccharide deacetylase family protein	-
V471_RS00470 (V471_00475)	-	95799..96563 (+)	765	WP_037599202.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V471_RS00475 (V471_00480)	-	96567..96836 (+)	270	WP_084870988.1	GIY-YIG nuclease family protein	-
V471_RS00480 (V471_00485)	-	96928..97314 (-)	387	WP_002886743.1	IS110 family transposase	-
V471_RS00485 (V471_00490)	-	97334..98095 (-)	762	WP_002886742.1	IS110 family transposase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84558.53 Da
• Isoelectric Point: 9.9425

>NTDB_id=178260 V471_RS00450 WP_084870985.1 90892..93132(-) (comEC/celB) [Streptococcus salivarius strain ATCC 25975]
MWLKKAPINLFSLALLIAALYFTIFVTNVYAMGAFAFLLVCFLKHHWKNKAALKLVGLVGGFFLIYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKYEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRMAQIEHLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLLIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFVLSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRVCLLMIFSLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKALIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVTKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETLKRFKKRH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=178260 V471_RS00450 WP_084870985.1 90892..93132(-) (comEC/celB) [Streptococcus salivarius strain ATCC 25975]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATGGGGGCTTTTGCTTTTCTTTTAGTATGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTGGGTTCTTTTTGATTTATTTTTTATTCTTGCATCACAGAGCTAGCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATATGAGAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTAGTACTAAAAGGAAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAGCACTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAGAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCAGGGATGCAAGTCGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTAATTATCTTGCTGCCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCT
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGTATAACCTTGCTTTTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTCTTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGTCCTTTCAGGACTAGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCCCAGTTTAGGGTTTGTCTTTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGCTCAAAGGAAAAATGGCAAGAGGCTAGTCAGACGAGCAATG
CGGAGAAAGCCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGACCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAATTGGTGATGGTGGTAACAATGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCCAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCTTTTTTGGACCAGCTGCATCCCTCCC
TTGCACTTGTTTCAGCCGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACTTTGAAGCGTTTTAAGAAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGCGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-696)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.391	100	0.484
comEC/celB	Streptococcus mitis SK321	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae R6	47.39	100	0.475
comEC/celB	Streptococcus pneumoniae D39	47.39	100	0.475
comEC/celB	Streptococcus pneumoniae Rx1	47.39	100	0.475
comEC/celB	Streptococcus pneumoniae TIGR4	47.122	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.108	99.196	0.428