Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   NX99_RS09730 Genome accession   NZ_CP015282
Coordinates   2076712..2078586 (+) Length   624 a.a.
NCBI ID   WP_084915458.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2071712..2083586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS09715 (NX99_09560) fmt 2073684..2074619 (+) 936 WP_084915456.1 methionyl-tRNA formyltransferase -
  NX99_RS09720 (NX99_09565) rsmB 2074609..2075931 (+) 1323 WP_084915504.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NX99_RS09725 (NX99_09570) - 2075975..2076712 (+) 738 WP_037598574.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NX99_RS09730 (NX99_09575) stkP/pknB 2076712..2078586 (+) 1875 WP_084915458.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NX99_RS09735 (NX99_09580) - 2078734..2079492 (+) 759 WP_084915460.1 potassium channel family protein -
  NX99_RS09740 (NX99_09585) liaF 2079654..2080352 (+) 699 WP_084915461.1 cell wall-active antibiotics response protein LiaF -
  NX99_RS09745 (NX99_09590) - 2080349..2081359 (+) 1011 WP_084915463.1 sensor histidine kinase -
  NX99_RS09750 (NX99_09595) - 2081349..2081993 (+) 645 WP_002884791.1 response regulator transcription factor -
  NX99_RS09765 (NX99_09610) rimM 2082688..2083206 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67901.59 Da        Isoelectric Point: 6.4576

>NTDB_id=178257 NX99_RS09730 WP_084915458.1 2076712..2078586(+) (stkP/pknB) [Streptococcus salivarius strain ATCC 27945]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=178257 NX99_RS09730 WP_084915458.1 2076712..2078586(+) (stkP/pknB) [Streptococcus salivarius strain ATCC 27945]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAGAAGTGGCCATTAAGGTCCTTCGTACCAATTACCAAACAGATCAGGTGG
CTGTGGCGCGTTTTCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACCAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTAACAGGTCATATTCCTTATGATG
GCGATAGTGCGGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAATTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TACCGAAGGTTGATCCAGTTCCATCAGCAAGCCTTGAGAAAAAGGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCGAGGAAGAAAACGACACCAGCTAAGAAGAAAAAGAAGAAGAATTTCTTCTCAACCTTACTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGTCGGCCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGATTCTGTCGATACGGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCAT
TGATATCTATGTTTCTTCCGGTAGTAAAGGTTTTGCGTTGAAAGACTACAAAGGTAAAAACTACAAAGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGTATCGAGTACCATGACTATAATACTGGTGCCAAGTTAGACAAGGATAAGGTTCCTAGCAGTACAGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCAGTTGCAACAGCAAGTTCAAG
TCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(511-580)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.878

100

0.989
  pknB Streptococcus mutans UA159

67.528

86.859

0.587
  stkP Streptococcus pneumoniae D39

52.324

93.109

0.487
  stkP Streptococcus pneumoniae R6

52.324

93.109

0.487
  stkP Streptococcus pneumoniae Rx1

52.151

93.109

0.486
  stkP Streptococcus pneumoniae TIGR4

52.439

91.987

0.482

Multiple sequence alignment