Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NX99_RS05980 Genome accession   NZ_CP015282
Coordinates   1356605..1357354 (-) Length   249 a.a.
NCBI ID   WP_014633817.1    Uniprot ID   A0AB35IU89
Organism   Streptococcus salivarius strain ATCC 27945     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1351605..1362354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS05960 (NX99_05860) - 1351927..1353159 (-) 1233 WP_084915093.1 cysteine desulfurase -
  NX99_RS05965 (NX99_05865) sufD 1353213..1354475 (-) 1263 WP_048790376.1 Fe-S cluster assembly protein SufD -
  NX99_RS05970 (NX99_05870) sufC 1354512..1355282 (-) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  NX99_RS05975 (NX99_05875) - 1355444..1356601 (-) 1158 WP_002883603.1 glycosyltransferase family 4 protein -
  NX99_RS05980 (NX99_05880) mecA 1356605..1357354 (-) 750 WP_014633817.1 adaptor protein MecA Regulator
  NX99_RS05985 (NX99_05885) - 1357561..1357932 (+) 372 WP_022496532.1 DUF3021 family protein -
  NX99_RS05990 (NX99_05890) - 1357994..1358848 (-) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  NX99_RS05995 (NX99_05895) - 1359054..1360601 (+) 1548 WP_084915095.1 ABC transporter substrate-binding protein/permease -
  NX99_RS06000 (NX99_05900) - 1360601..1361341 (+) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29100.68 Da        Isoelectric Point: 4.0182

>NTDB_id=178224 NX99_RS05980 WP_014633817.1 1356605..1357354(-) (mecA) [Streptococcus salivarius strain ATCC 27945]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDIPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=178224 NX99_RS05980 WP_014633817.1 1356605..1357354(-) (mecA) [Streptococcus salivarius strain ATCC 27945]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCATTATGTCTTGGCCTTC
TCTGACTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATATACCTGTTGAAGGTTCTGAGCTTTATAAGCTGGG
GGATGTCTACTACATGACGATTCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment