Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   A6B45_RS09520 Genome accession   NZ_CP015247
Coordinates   1898169..1899308 (-) Length   379 a.a.
NCBI ID   WP_072614345.1    Uniprot ID   -
Organism   Leuconostoc suionicum strain DSM 20241     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1893169..1904308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6B45_RS09500 (A6B45_09370) - 1893546..1894211 (+) 666 WP_072614341.1 NAD(P)H-hydrate epimerase -
  A6B45_RS09505 (A6B45_09375) - 1894276..1894746 (-) 471 WP_072614342.1 Rrf2 family transcriptional regulator -
  A6B45_RS09510 (A6B45_09380) - 1894800..1896965 (-) 2166 WP_072614343.1 YhgE/Pip domain-containing protein -
  A6B45_RS09515 (A6B45_09385) rlmH 1897059..1897538 (-) 480 WP_072614344.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A6B45_RS09520 (A6B45_09390) htrA 1898169..1899308 (-) 1140 WP_072614345.1 S1C family serine protease Regulator
  A6B45_RS09525 (A6B45_09395) yycI 1899369..1900163 (-) 795 WP_072614346.1 two-component system regulatory protein YycI -
  A6B45_RS09530 (A6B45_09400) - 1900222..1901514 (-) 1293 WP_072614347.1 hypothetical protein -
  A6B45_RS09535 (A6B45_09405) walK 1901504..1903369 (-) 1866 WP_072614348.1 cell wall metabolism sensor histidine kinase WalK -
  A6B45_RS09540 (A6B45_09410) yycF 1903437..1904144 (-) 708 WP_010281559.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39216.53 Da        Isoelectric Point: 9.9329

>NTDB_id=178027 A6B45_RS09520 WP_072614345.1 1898169..1899308(-) (htrA) [Leuconostoc suionicum strain DSM 20241]
MVQSALTKTLLTGVIAGVVGGGAILYGQQGVQLLQNQNQKVSTTATSTKTIAKNATATSAYNKVSDAVVSVLNFTKSSQG
SYQESSEGSGVIYKKTDGSAFIVTNNHVITGAAKIQVMLHSGKKVTATLVGKDAMTDLAVLKIDGTDVTTTAQFGDSSKI
TVGENVLAIGSPLGSEYASSVTQGIISAKKRLVETTSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
TSSSGTSVEGMGFAIPSDQVVDIVNKLVKNGKVTRPAIGISLINLSEVTASEQKSTLKIPDSVTGGVVVMSLTNNGPADK
AGLKKYDVIVGINGKKVSSQADLREELYKNSLGDTITLTYYHQDTKKTVKVKLTQKLAS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=178027 A6B45_RS09520 WP_072614345.1 1898169..1899308(-) (htrA) [Leuconostoc suionicum strain DSM 20241]
ATGGTACAATCAGCATTAACAAAAACGTTGTTAACTGGCGTCATTGCTGGTGTTGTTGGTGGAGGAGCAATTTTGTATGG
GCAACAAGGTGTACAATTGTTACAAAATCAAAATCAAAAAGTAAGTACGACAGCAACAAGTACAAAAACGATTGCCAAGA
ATGCAACCGCTACATCAGCTTATAATAAGGTATCAGATGCAGTTGTATCTGTATTAAACTTTACTAAATCTAGTCAAGGT
AGTTATCAAGAATCGTCAGAAGGTTCTGGCGTGATCTATAAAAAAACAGATGGGTCGGCATTTATTGTAACGAATAATCA
CGTCATCACTGGAGCGGCTAAAATTCAAGTTATGCTGCACAGTGGGAAGAAAGTGACCGCAACACTAGTCGGCAAAGATG
CGATGACTGACTTAGCTGTTCTGAAGATCGACGGCACAGACGTTACGACAACTGCACAATTTGGCGATTCAAGTAAAATA
ACTGTTGGTGAAAACGTCTTGGCAATTGGTTCGCCGCTGGGATCTGAGTATGCTTCGTCAGTGACGCAAGGTATCATTTC
TGCCAAAAAAAGGTTAGTTGAGACGACATCTGAAAATGGGCAGAATTATGGTGGATCCACGGTTATTCAGACGGATGCTG
CCATTAACCCTGGTAACTCAGGGGGACCATTAATTAATTTTGCAGGACAAGTTATTGGTATTAACTCAATGAAGTTATCA
ACATCTTCTTCGGGAACGAGCGTTGAGGGGATGGGTTTTGCAATTCCTTCTGATCAAGTCGTTGACATTGTTAACAAATT
AGTCAAAAATGGTAAGGTCACACGACCAGCAATCGGTATTAGCTTGATTAATTTGTCGGAAGTAACAGCTTCTGAGCAAA
AATCAACTTTGAAAATTCCAGATAGTGTTACTGGTGGTGTTGTAGTAATGAGTTTGACTAACAATGGCCCAGCGGATAAA
GCTGGATTGAAAAAGTACGATGTTATCGTTGGCATTAATGGTAAAAAGGTAAGTTCACAGGCTGATCTGCGAGAAGAACT
GTACAAGAATTCGCTTGGGGACACAATAACATTGACTTATTATCATCAGGATACTAAGAAGACAGTCAAGGTTAAATTAA
CACAGAAATTAGCAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Peptidase family M50 (Peptidase_M50)

(221-375)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

52.394

93.668

0.491
  htrA Streptococcus gordonii str. Challis substr. CH1

48.285

100

0.483
  htrA Streptococcus pneumoniae D39

52.924

90.237

0.478
  htrA Streptococcus pneumoniae TIGR4

52.924

90.237

0.478
  htrA Streptococcus pneumoniae R6

52.924

90.237

0.478
  htrA Streptococcus pneumoniae Rx1

52.924

90.237

0.478
  htrA Streptococcus mutans UA159

52.819

88.918

0.47

Multiple sequence alignment