Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   A4H00_RS08800 Genome accession   NZ_CP015196
Coordinates   1775284..1775958 (+) Length   224 a.a.
NCBI ID   WP_067089716.1    Uniprot ID   -
Organism   Streptococcus marmotae strain HTS5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770284..1780958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4H00_RS08775 pstC 1771128..1772045 (+) 918 WP_067089696.1 phosphate ABC transporter permease subunit PstC -
  A4H00_RS08780 pstA 1772035..1772922 (+) 888 WP_067089699.1 phosphate ABC transporter permease PstA -
  A4H00_RS08785 pstB 1772938..1773741 (+) 804 WP_067089704.1 phosphate ABC transporter ATP-binding protein PstB -
  A4H00_RS08790 pstB 1773754..1774512 (+) 759 WP_067089708.1 phosphate ABC transporter ATP-binding protein PstB -
  A4H00_RS08795 phoU 1774531..1775187 (+) 657 WP_067089712.1 phosphate signaling complex protein PhoU -
  A4H00_RS08800 ciaR 1775284..1775958 (+) 675 WP_067089716.1 response regulator transcription factor Regulator
  A4H00_RS08805 - 1775948..1777334 (+) 1387 Protein_1690 sensor histidine kinase -
  A4H00_RS08810 - 1777818..1779320 (+) 1503 WP_067089719.1 LPXTG cell wall anchor domain-containing protein -
  A4H00_RS08815 - 1779712..1780542 (+) 831 Protein_1692 metal ABC transporter solute-binding protein, Zn/Mn family -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25339.99 Da        Isoelectric Point: 4.3279

>NTDB_id=177453 A4H00_RS08800 WP_067089716.1 1775284..1775958(+) (ciaR) [Streptococcus marmotae strain HTS5]
MIKILLVEDDVSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELRTKGITTPVLITTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENVLTFGDVTVDLSTNTTTVNGEEVEFLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTAFGEQLQTLRSVGYILKNAH

Nucleotide


Download         Length: 675 bp        

>NTDB_id=177453 A4H00_RS08800 WP_067089716.1 1775284..1775958(+) (ciaR) [Streptococcus marmotae strain HTS5]
ATGATTAAGATTTTATTAGTAGAAGACGATGTAAGTTTATCCAATTCAGTCTTTGATTTTTTAGATGATTTTGCGGATGT
GATGCAGGTATTTGACGGCGAAGAAGGCTTGTATGAGGCGGAATCAGGAGTGTATGACCTCATCTTGCTTGATTTGATGT
TACCAGAAAAGAATGGCTTTCAAGTGTTGAAAGAATTACGAACCAAAGGTATTACAACGCCTGTCTTGATTACGACGGCC
AAGGAAAGTTTGGACGATAAGGGACATGGGTTTGAACTTGGAGCAGATGACTATCTGACCAAACCCTTTTATTTGGAAGA
GTTGAAAATGCGCATCCAAGCCCTTCTGAAGCGTGCTGGGAAATTCAACGAAAATGTTTTGACCTTTGGGGATGTAACTG
TTGATTTATCGACCAATACGACAACCGTAAATGGGGAAGAAGTAGAATTTTTGGGGAAAGAATTTGACTTATTAGTCTAC
TTTTTACAGAATCAAAATGTGATTTTGCCGAAAACACAGATTTTTGATCGCCTTTGGGGGTTTGACAGTGATACGACAAT
CTCAGTAGTAGAAGTCTATGTCTCTAAAATTAGAAAAAAATTGAAAGGGACGGCCTTTGGGGAGCAATTACAGACTCTAA
GAAGTGTCGGATATATCTTGAAAAATGCTCATTAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.286

100

0.893
  ciaR Streptococcus pneumoniae Rx1

88.393

100

0.884
  ciaR Streptococcus pneumoniae D39

88.393

100

0.884
  ciaR Streptococcus pneumoniae R6

88.393

100

0.884
  ciaR Streptococcus pneumoniae TIGR4

88.393

100

0.884
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.053

100

0.384
  vicR Streptococcus mutans UA159

34.615

100

0.362

Multiple sequence alignment