Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   A4H00_RS03730 Genome accession   NZ_CP015196
Coordinates   747223..748119 (-) Length   298 a.a.
NCBI ID   WP_067087444.1    Uniprot ID   -
Organism   Streptococcus marmotae strain HTS5     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 748439..748912 747223..748119 flank 320


Gene organization within MGE regions


Location: 747223..748912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4H00_RS03730 comR 747223..748119 (-) 897 WP_067087444.1 helix-turn-helix domain-containing protein Regulator
  A4H00_RS03735 tnpA 748439..748912 (-) 474 WP_067087447.1 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 298 a.a.        Molecular weight: 35472.80 Da        Isoelectric Point: 4.5822

>NTDB_id=177431 A4H00_RS03730 WP_067087444.1 747223..748119(-) (comR) [Streptococcus marmotae strain HTS5]
MDNKEFGAKVRRLRENLGITREQFCEDEVELTARQLMRIEAGQSKPTLSKITFIAQRLGMTLYQLMPDYVELPSRYTKLK
YDVLRVPTYGKPELVEKREALLEEIYDDFYDRLPEEEKIAIDAFRSALDVAETQTAHFGQEIIDEYFFQIRQKDSYKIND
LLIIRLYIERIKYWQEEEQFPDFLELLEVLVHQVDVVIAEDLFVLRDVLMAAIGILGKSGKYEFFPRLFKALDDIMMMSQ
DFQKKPILSMLKWKYELFHTKNREQATFYYEEAINFAQLIGNTYLAERLEAEWQENIA

Nucleotide


Download         Length: 897 bp        

>NTDB_id=177431 A4H00_RS03730 WP_067087444.1 747223..748119(-) (comR) [Streptococcus marmotae strain HTS5]
GTGGATAACAAAGAATTTGGGGCAAAAGTTCGACGATTGCGGGAAAATTTGGGTATTACTAGAGAGCAGTTTTGTGAAGA
TGAAGTTGAATTAACTGCTCGACAGTTGATGCGGATAGAAGCCGGACAATCTAAGCCAACATTGAGCAAAATTACCTTCA
TTGCCCAACGTTTGGGTATGACTCTTTATCAATTGATGCCGGATTATGTCGAGTTGCCATCTCGTTATACAAAGTTAAAG
TACGATGTGTTACGTGTACCTACATACGGAAAGCCTGAATTAGTAGAGAAACGTGAGGCTCTCTTAGAAGAAATCTATGA
TGACTTCTATGATAGATTACCAGAAGAAGAAAAGATAGCGATAGATGCCTTTCGGTCAGCGCTAGATGTTGCAGAAACGC
AAACAGCACACTTTGGTCAGGAAATTATTGATGAGTACTTTTTTCAGATCCGCCAGAAAGATTCGTATAAAATTAATGAT
TTGTTAATTATACGCCTCTATATAGAACGCATAAAATATTGGCAAGAAGAAGAGCAGTTTCCAGATTTTTTAGAGTTACT
AGAAGTCTTAGTCCATCAAGTAGATGTCGTAATCGCAGAAGACTTATTTGTCCTGCGTGACGTTCTAATGGCAGCAATTG
GGATATTAGGAAAATCGGGAAAATACGAATTTTTTCCTAGACTATTCAAAGCTTTAGATGACATCATGATGATGAGTCAG
GATTTTCAGAAGAAGCCAATTTTGAGTATGCTAAAGTGGAAATATGAGTTATTCCATACAAAGAATAGGGAACAAGCAAC
ATTTTACTATGAAGAAGCGATTAATTTTGCTCAGCTAATTGGGAATACATATCTTGCAGAGCGACTGGAAGCGGAATGGC
AGGAAAATATTGCCTAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-293)

Helix-turn-helix domain (HTH_19)

(7-68)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

55.254

98.993

0.547
  comR Streptococcus suis 05ZYH33

55.254

98.993

0.547
  comR Streptococcus suis D9

50.836

100

0.51
  comR Streptococcus mutans UA159

45.118

99.664

0.45
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.446

96.98

0.383
  comR Streptococcus pyogenes MGAS315

37.71

99.664

0.376

Multiple sequence alignment