Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A4H00_RS01600 Genome accession   NZ_CP015196
Coordinates   317130..317858 (-) Length   242 a.a.
NCBI ID   WP_067086483.1    Uniprot ID   -
Organism   Streptococcus marmotae strain HTS5     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 312130..322858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4H00_RS01575 sufU 312168..312602 (-) 435 WP_067086470.1 Fe-S cluster assembly sulfur transfer protein SufU -
  A4H00_RS01580 - 312589..313818 (-) 1230 WP_067086471.1 cysteine desulfurase -
  A4H00_RS01585 sufD 313824..315086 (-) 1263 WP_067086474.1 Fe-S cluster assembly protein SufD -
  A4H00_RS01590 sufC 315116..315886 (-) 771 WP_067086477.1 Fe-S cluster assembly ATPase SufC -
  A4H00_RS01595 - 315967..317133 (-) 1167 WP_067086480.1 glycosyltransferase family 4 protein -
  A4H00_RS01600 mecA 317130..317858 (-) 729 WP_067086483.1 adaptor protein MecA Regulator
  A4H00_RS01605 - 318253..319092 (-) 840 WP_067086486.1 undecaprenyl-diphosphate phosphatase -
  A4H00_RS01610 - 319219..320784 (+) 1566 WP_067086488.1 ABC transporter substrate-binding protein/permease -
  A4H00_RS01615 - 320777..321526 (+) 750 WP_067086491.1 amino acid ABC transporter ATP-binding protein -
  A4H00_RS01620 - 321611..321820 (-) 210 WP_009910800.1 hypothetical protein -
  A4H00_RS01625 - 321906..322799 (-) 894 WP_067091370.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28170.78 Da        Isoelectric Point: 4.0198

>NTDB_id=177414 A4H00_RS01600 WP_067086483.1 317130..317858(-) (mecA) [Streptococcus marmotae strain HTS5]
MKMKQISDSTLKITIKMEDLEERGMELADFLVPQEKTEEFFYAVLDELELPVTFRESGMLSFRVTPKPDKVDIFVTKSDI
DQQLNFDDFADMADLDELSQMTPDEFLKTLEKTIREKSVGDNRAVQHLEQVEETEFDDEEDVEVRNYIYYILDFASLQEA
VQFVSLVDFTVEESELYKMNERYYMTVLINIENRSTRYPDYILSRMLEHADDTSISRAVLQEHGVLLLPVGAIDELGKVN
LA

Nucleotide


Download         Length: 729 bp        

>NTDB_id=177414 A4H00_RS01600 WP_067086483.1 317130..317858(-) (mecA) [Streptococcus marmotae strain HTS5]
ATGAAGATGAAACAAATTAGTGATTCCACCTTGAAAATCACAATAAAGATGGAAGATTTGGAAGAGCGTGGAATGGAATT
GGCGGATTTTCTAGTACCACAGGAAAAAACAGAAGAATTTTTCTATGCCGTGCTAGATGAACTAGAATTACCAGTAACCT
TCCGTGAAAGTGGGATGCTGAGTTTTCGTGTGACGCCAAAACCAGATAAGGTGGATATTTTTGTAACGAAATCAGATATT
GATCAGCAATTGAATTTTGATGATTTTGCGGATATGGCCGATTTAGATGAGCTGTCACAAATGACACCAGATGAATTTTT
GAAGACACTTGAGAAAACGATTCGTGAAAAGAGCGTAGGGGATAATCGAGCAGTTCAACATTTGGAGCAGGTAGAGGAAA
CGGAATTTGATGACGAAGAGGACGTAGAAGTTCGCAATTATATCTATTACATTCTTGATTTTGCAAGTCTTCAGGAGGCT
GTTCAGTTTGTGTCCCTTGTTGATTTTACAGTTGAAGAATCAGAATTGTACAAGATGAATGAACGCTACTATATGACAGT
TTTGATCAATATTGAAAATCGTTCAACACGCTACCCAGACTATATCTTGTCACGAATGCTGGAGCATGCAGATGATACGT
CAATCTCACGTGCTGTCCTGCAAGAGCATGGGGTTCTCCTGCTTCCAGTTGGTGCTATTGATGAGCTTGGGAAGGTGAAC
TTAGCATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

60.408

100

0.612
  mecA Streptococcus pneumoniae D39

60.408

100

0.612
  mecA Streptococcus pneumoniae R6

60.408

100

0.612
  mecA Streptococcus pneumoniae TIGR4

60.408

100

0.612
  mecA Streptococcus mutans UA159

52.282

99.587

0.521
  mecA Streptococcus thermophilus LMD-9

46.531

100

0.471
  mecA Streptococcus thermophilus LMG 18311

46.122

100

0.467

Multiple sequence alignment