Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A2G56_RS05850 Genome accession   NZ_CP014835
Coordinates   1300949..1301713 (-) Length   254 a.a.
NCBI ID   WP_062710284.1    Uniprot ID   -
Organism   Streptococcus halotolerans strain HTS9     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1295949..1306713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2G56_RS05830 sufD 1297010..1298272 (-) 1263 WP_062710272.1 Fe-S cluster assembly protein SufD -
  A2G56_RS05835 - 1298273..1298818 (-) 546 WP_157761200.1 GNAT family N-acetyltransferase -
  A2G56_RS05840 sufC 1298799..1299575 (-) 777 WP_062710278.1 Fe-S cluster assembly ATPase SufC -
  A2G56_RS05845 - 1299788..1300948 (-) 1161 WP_062710281.1 glycosyltransferase family 4 protein -
  A2G56_RS05850 mecA 1300949..1301713 (-) 765 WP_062710284.1 adaptor protein MecA Regulator
  A2G56_RS05855 - 1301792..1302316 (-) 525 WP_062710287.1 phosphatase PAP2 family protein -
  A2G56_RS05860 - 1302389..1302610 (-) 222 WP_062710289.1 DUF4649 family protein -
  A2G56_RS05865 - 1302620..1302976 (-) 357 WP_062710292.1 DUF2200 domain-containing protein -
  A2G56_RS05870 - 1303858..1305342 (+) 1485 WP_062710294.1 DUF1846 domain-containing protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29199.89 Da        Isoelectric Point: 4.2337

>NTDB_id=174479 A2G56_RS05850 WP_062710284.1 1300949..1301713(-) (mecA) [Streptococcus halotolerans strain HTS9]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPKKDRLDVFVTKSEI
DKDLNLEDLANFGDVSQMSPDEFFKTLEKSMLEKGDTEAHEKLKRMEDIVESAMSEMSSEPEATVAEAEDEDDTENQSYT
HYVLSFPSLKEAVIFSKAIDFEIEASELYKLAGQYYMTILVGLENKPAYYANLVHARLLEHSQNAQKTRAYLQEHGIRLI
DGYAVAELEGIKVH

Nucleotide


Download         Length: 765 bp        

>NTDB_id=174479 A2G56_RS05850 WP_062710284.1 1300949..1301713(-) (mecA) [Streptococcus halotolerans strain HTS9]
ATGGAAATGAAACAAATTAGCGAAACGACGCTAAAAATTACGATTAGTATGGAAGATTTAGAAGAAAGAGGAATGGAGTT
AAAAGATTTTCTTATTCCTCAAGAAAAAACAGAAGAATTTTTCTATACTGTTATGGATGAACTAGATCTACCAGATAACT
TCAAAAATAGTGGTATGCTAAGCTTTCGCGTGACCCCTAAGAAGGATCGCTTGGACGTCTTTGTGACAAAATCAGAAATT
GATAAAGATCTTAATTTAGAAGACCTAGCTAATTTTGGCGATGTGTCTCAGATGTCTCCAGATGAATTCTTTAAAACATT
AGAAAAATCAATGTTGGAAAAAGGGGATACGGAAGCTCATGAGAAATTAAAACGAATGGAAGACATAGTAGAATCAGCGA
TGTCAGAAATGTCTTCTGAGCCCGAGGCGACAGTAGCAGAGGCTGAAGATGAGGATGATACTGAAAATCAATCTTACACG
CACTATGTCCTCAGTTTTCCATCACTGAAAGAAGCGGTTATTTTTTCCAAAGCTATCGATTTCGAGATTGAAGCGTCAGA
ATTGTATAAATTAGCTGGACAATACTATATGACTATCCTAGTCGGTTTAGAAAATAAGCCAGCTTATTACGCTAATCTTG
TCCATGCTCGACTGTTAGAACATAGCCAAAACGCTCAAAAAACGAGAGCATATCTTCAAGAACATGGTATCCGTTTGATT
GATGGTTATGCTGTAGCGGAACTAGAGGGTATAAAGGTGCACTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.355

98.819

0.606
  mecA Streptococcus thermophilus LMD-9

56.917

99.606

0.567
  mecA Streptococcus thermophilus LMG 18311

56.126

99.606

0.559
  mecA Streptococcus pneumoniae Rx1

48.828

100

0.492
  mecA Streptococcus pneumoniae D39

48.828

100

0.492
  mecA Streptococcus pneumoniae R6

48.828

100

0.492
  mecA Streptococcus pneumoniae TIGR4

48.828

100

0.492

Multiple sequence alignment