Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BSR14_RS09295 Genome accession   NZ_CP018186
Coordinates   2013909..2014652 (-) Length   247 a.a.
NCBI ID   WP_002886967.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC1     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2008909..2019652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR14_RS09280 (BSR14_09385) argH 2008964..2010349 (-) 1386 WP_037601513.1 argininosuccinate lyase -
  BSR14_RS09285 (BSR14_09390) - 2010676..2011875 (-) 1200 WP_156209964.1 argininosuccinate synthase -
  BSR14_RS09290 (BSR14_09395) - 2012876..2013757 (-) 882 WP_269434100.1 IS30 family transposase -
  BSR14_RS09295 (BSR14_09400) comE/blpR 2013909..2014652 (-) 744 WP_002886967.1 response regulator transcription factor Regulator
  BSR14_RS09300 (BSR14_09405) - 2014654..2015940 (-) 1287 WP_228382827.1 GHKL domain-containing protein -
  BSR14_RS09305 (BSR14_09410) - 2015994..2017274 (-) 1281 WP_049529279.1 hypothetical protein -
  BSR14_RS09310 (BSR14_09415) - 2017296..2018186 (-) 891 WP_149561142.1 histidine kinase -
  BSR14_RS09315 (BSR14_09420) - 2018246..2019553 (-) 1308 WP_002885760.1 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28533.89 Da        Isoelectric Point: 7.0533

>NTDB_id=173557 BSR14_RS09295 WP_002886967.1 2013909..2014652(-) (comE/blpR) [Streptococcus salivarius strain ICDC1]
MNIYILEDDLMQQTRISDIIRELVSEGAFSVRKLEVFSKPHKLLSSINEKGNHQIFLLDIDIDGNRKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIEKTVSNVEFKQQLKQTLTFVNQKIGDVDDDEMFVFETAQSRIQVPMRDIYY
FATAATPHKVMLITKTERLEFYANLGDITSVNKILFSCHRSFLVNLDNIARIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVRNH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=173557 BSR14_RS09295 WP_002886967.1 2013909..2014652(-) (comE/blpR) [Streptococcus salivarius strain ICDC1]
ATGAATATATATATTTTAGAAGATGATTTGATGCAACAAACACGTATTAGTGATATCATCAGAGAATTGGTTTCAGAGGG
TGCGTTTTCTGTACGAAAACTTGAAGTTTTTTCTAAACCACATAAACTATTGTCCAGCATCAATGAGAAGGGGAACCATC
AGATTTTTCTTTTGGATATTGATATTGATGGCAATCGAAAGAAGGGGTTAGAAGTTGCCTCTGAAATTCGTCAACAAGAT
GCTAATGCGGTTATTATTTTTGTAACAACTCACTCAGAATTTGCTCCAATTAGTTTTAAGTATAAGGTTTCCGCACTTGA
TTTTATTGAAAAGACAGTCTCTAATGTGGAATTCAAACAACAATTGAAACAAACCTTGACTTTTGTAAATCAAAAAATTG
GAGATGTGGACGATGATGAGATGTTTGTGTTTGAAACTGCTCAGTCTAGAATACAAGTTCCGATGCGAGATATTTATTAT
TTTGCGACAGCTGCAACTCCTCATAAGGTAATGTTAATTACTAAAACAGAGCGCCTGGAGTTTTATGCTAATCTTGGAGA
TATTACTTCGGTGAATAAAATACTCTTTTCATGTCACCGCTCCTTTTTAGTTAATCTGGATAATATTGCCCGTATTGATA
AGACGCAACTGATGATTTATTTTGAGAATGGTGATTCATGTCCGGTTTCTCGCTTGAAAATGAAGGCCCTACTTAAAAAA
TGGTCAGAGGTAAGAAATCATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.083

97.166

0.457
  comE/comE2 Streptococcus equinus JB1

41.633

99.19

0.413
  comE/comE1 Streptococcus equinus JB1

39.669

97.976

0.389
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.929

97.571

0.36
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.929

97.571

0.36