Detailed information NTG0173378

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A0O21_RS09630
• Genome accession: NZ_CP014699
• Coordinates: 2086400..2087527 (+)
• Length: 375 a.a.
• NCBI ID: WP_418346444.1
• Uniprot ID: -
• Organism: Streptococcus pantholopis strain TA 26
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2081400..2092527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A0O21_RS09605 (A0O21_09605)	-	2082279..2084873 (+)	2595	WP_418346443.1	YfhO family protein	-
A0O21_RS09625 (A0O21_09625)	rlmH	2085651..2086130 (-)	480	WP_067064661.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A0O21_RS09630 (A0O21_09630)	htrA	2086400..2087527 (+)	1128	WP_418346444.1	S1C family serine protease	Regulator
A0O21_RS09635 (A0O21_09635)	spo0J	2087656..2088423 (+)	768	WP_067064665.1	ParB/RepB/Spo0J family partition protein	Regulator
A0O21_RS09640 (A0O21_09640)	dnaA	2088627..2089985 (+)	1359	WP_067064667.1	chromosomal replication initiator protein DnaA	-
A0O21_RS09645 (A0O21_09645)	dnaN	2090138..2091271 (+)	1134	WP_067064668.1	DNA polymerase III subunit beta	-
A0O21_RS09650 (A0O21_09650)	-	2091315..2092199 (+)	885	WP_067064670.1	diacylglycerol/lipid kinase family protein	-
A0O21_RS09655 (A0O21_09655)	-	2092268..2092474 (+)	207	WP_067064672.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 375 a.a.
• Molecular weight: 39168.08 Da
• Isoelectric Point: 3.9974

>NTDB_id=173378 A0O21_RS09630 WP_418346444.1 2086400..2087527(+) (htrA) [Streptococcus pantholopis strain TA 26]
MGGILGATVTNYLNNHPENTTTKTSNVTYNNTTDTTEAVKTIQNAVVSVVNYQKASSSDMYSDIFGGDSSSASDSDSDLQ
VASQGSGVIYKKEGDSAYVVTNNHVIDGAEQIEILLADGTKVVGKLVGADTYSDLAVVQIPSENVKTVAEFADSSKINVG
EIAIAIGSPLGTDYANSVTQGIVSSLSRTVTLTNNNGETISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSN
SESVEGMGFAIPSNDVVKIINQLEENGEVVRPALGISMANLSDLSTSVINKLNIPESVTNGIVVGSVQSDMPASGKLEQY
DVITEIDGQEVTSTSDLQSILYDHEIGDSVKVTFYRGNDKKTVTIDLTKTTQDLS

Nucleotide

• Length: 1128 bp

>NTDB_id=173378 A0O21_RS09630 WP_418346444.1 2086400..2087527(+) (htrA) [Streptococcus pantholopis strain TA 26]
ATTGGTGGAATTTTAGGAGCAACTGTTACAAATTATCTCAATAATCACCCGGAAAACACTACAACAAAAACAAGCAATGT
GACTTACAATAATACTACTGACACAACAGAGGCAGTTAAAACAATCCAAAATGCTGTGGTTTCTGTCGTTAACTACCAAA
AAGCATCTTCTTCAGATATGTACAGTGATATATTTGGCGGAGACAGCAGCTCAGCATCAGACAGTGATTCAGATTTGCAA
GTTGCCAGTCAAGGGTCTGGTGTTATTTATAAAAAAGAAGGAGATTCTGCTTACGTTGTTACCAATAATCACGTTATTGA
CGGAGCTGAGCAGATTGAAATTCTTTTGGCTGATGGAACAAAAGTGGTTGGAAAACTAGTTGGTGCAGATACTTACTCCG
ATTTAGCTGTTGTCCAAATCCCATCTGAAAACGTAAAAACTGTAGCCGAATTTGCTGACTCTTCTAAAATTAATGTCGGA
GAAATTGCCATTGCTATTGGAAGCCCATTAGGTACAGATTATGCCAATTCTGTTACCCAAGGAATTGTGTCCAGTCTCAG
CCGTACTGTAACACTTACAAACAATAACGGTGAAACAATTTCGACAAATGCTATTCAGACAGATGCAGCAATTAATCCTG
GTAATTCCGGTGGTGCTTTGATTAATATTGAAGGACAGGTTATCGGTATCAATTCAAGCAAGATCTCTTCAACATCAAAC
AGTGAATCTGTAGAAGGGATGGGATTTGCTATTCCTTCCAATGATGTTGTAAAAATTATCAATCAACTTGAAGAAAACGG
TGAAGTTGTTCGTCCGGCTTTGGGTATTTCTATGGCTAATCTAAGTGATTTATCAACTAGTGTTATTAATAAGCTGAATA
TTCCTGAAAGTGTAACAAACGGCATTGTGGTTGGTTCTGTACAATCTGACATGCCGGCCAGCGGTAAATTAGAGCAGTAC
GATGTTATCACTGAAATTGACGGACAAGAAGTTACTTCTACCAGTGATCTTCAAAGTATTCTTTACGATCATGAGATTGG
TGATTCTGTCAAAGTAACCTTCTATCGCGGAAACGATAAGAAGACTGTAACAATTGACCTGACAAAGACCACTCAGGATT
TGTCATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (272-367)

• Trypsin-like peptidase domain (Trypsin_2) (85-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	67.196	100	0.677
htrA	Streptococcus gordonii str. Challis substr. CH1	58.225	100	0.595
htrA	Streptococcus mitis NCTC 12261	57.784	100	0.584
htrA	Streptococcus pneumoniae TIGR4	60.519	92.533	0.56
htrA	Streptococcus pneumoniae Rx1	60.519	92.533	0.56
htrA	Streptococcus pneumoniae D39	60.519	92.533	0.56
htrA	Streptococcus pneumoniae R6	60.519	92.533	0.56