Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   A0O21_RS04750 Genome accession   NZ_CP014699
Coordinates   1019266..1019940 (-) Length   224 a.a.
NCBI ID   WP_067062089.1    Uniprot ID   A0A172Q7C9
Organism   Streptococcus pantholopis strain TA 26     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1014266..1024940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS04725 (A0O21_04730) - 1014607..1015884 (-) 1278 WP_067062075.1 pyrimidine-nucleoside phosphorylase -
  A0O21_RS04730 (A0O21_04735) - 1015881..1016462 (-) 582 WP_067062078.1 class I SAM-dependent methyltransferase -
  A0O21_RS04735 (A0O21_04740) coaA 1016586..1017506 (+) 921 WP_067062080.1 type I pantothenate kinase -
  A0O21_RS04740 (A0O21_04745) rpsT 1017625..1017876 (+) 252 WP_082854412.1 30S ribosomal protein S20 -
  A0O21_RS04745 (A0O21_04750) ciaH 1017927..1019276 (-) 1350 WP_067062086.1 sensor histidine kinase Regulator
  A0O21_RS04750 (A0O21_04755) ciaR 1019266..1019940 (-) 675 WP_067062089.1 response regulator transcription factor Regulator
  A0O21_RS04755 (A0O21_04760) - 1020210..1022753 (-) 2544 WP_067062093.1 M1 family metallopeptidase -
  A0O21_RS04760 (A0O21_04765) phoU 1022795..1023448 (-) 654 WP_067062096.1 phosphate signaling complex protein PhoU -
  A0O21_RS04765 (A0O21_04770) pstB 1023458..1024216 (-) 759 WP_067062099.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25355.24 Da        Isoelectric Point: 4.4644

>NTDB_id=173352 A0O21_RS04750 WP_067062089.1 1019266..1019940(-) (ciaR) [Streptococcus pantholopis strain TA 26]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGIYEAESGVYDLILLDLMLPEKNGFQVLKELREKGVATPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNEKVLSYAELSVDTSTNTTLVKGEEVELLGKEFDLLVY
FLQNKNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFAKNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=173352 A0O21_RS04750 WP_067062089.1 1019266..1019940(-) (ciaR) [Streptococcus pantholopis strain TA 26]
ATGATTAAGATATTGCTTGTTGAAGATGATTTGGGCCTGTCTAATTCAGTGTTTGATTTTTTAGACGATTTTGCTGATGT
TATGCAGGTTTTTGATGGTGAAGAAGGGATCTATGAAGCTGAGAGCGGGGTTTATGATCTTATTTTATTAGATTTGATGC
TGCCGGAAAAAAACGGTTTTCAAGTTTTAAAAGAGCTGCGGGAAAAAGGAGTAGCAACACCGGTTCTTATTATGACTGCT
AAAGAGGGGCTTGATGACAAGGGACATGGTTTTGAACTAGGTGCAGATGACTATCTGACAAAACCTTTTTACCTTGAAGA
GCTAAAAATGCGCATCCAGGCTTTATTAAAACGTTCCGGGAAGTTCAATGAAAAGGTCCTTTCCTATGCTGAACTGTCAG
TTGATACCTCAACTAACACCACTCTAGTCAAGGGAGAAGAGGTTGAACTGCTGGGCAAGGAGTTTGATTTATTGGTCTAT
TTTTTGCAGAATAAGAATGTTATTCTGCCGAAGTCACAGATTTTTGACCGAATTTGGGGATTTGACAGTGATACAACGAT
TTCAGTTGTAGAGGTGTATGTTTCAAAAATCCGTAAAAAGTTAAAGGGAACAACTTTTGCTAAAAATCTACAAACATTGC
GCAGTGTGGGGTATATACTGAAAAATGCTGAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q7C9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

91.48

99.554

0.911
  ciaR Streptococcus pneumoniae Rx1

87.5

100

0.875
  ciaR Streptococcus pneumoniae D39

87.5

100

0.875
  ciaR Streptococcus pneumoniae R6

87.5

100

0.875
  ciaR Streptococcus pneumoniae TIGR4

87.5

100

0.875
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379

Multiple sequence alignment