Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   A0O21_RS04745 Genome accession   NZ_CP014699
Coordinates   1017927..1019276 (-) Length   449 a.a.
NCBI ID   WP_067062086.1    Uniprot ID   A0A172Q7E8
Organism   Streptococcus pantholopis strain TA 26     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1012927..1024276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS04715 (A0O21_04720) - 1013554..1013946 (-) 393 WP_067062072.1 cytidine deaminase -
  A0O21_RS04720 (A0O21_04725) deoC 1013933..1014595 (-) 663 WP_067065137.1 deoxyribose-phosphate aldolase -
  A0O21_RS04725 (A0O21_04730) - 1014607..1015884 (-) 1278 WP_067062075.1 pyrimidine-nucleoside phosphorylase -
  A0O21_RS04730 (A0O21_04735) - 1015881..1016462 (-) 582 WP_067062078.1 class I SAM-dependent methyltransferase -
  A0O21_RS04735 (A0O21_04740) coaA 1016586..1017506 (+) 921 WP_067062080.1 type I pantothenate kinase -
  A0O21_RS04740 (A0O21_04745) rpsT 1017625..1017876 (+) 252 WP_082854412.1 30S ribosomal protein S20 -
  A0O21_RS04745 (A0O21_04750) ciaH 1017927..1019276 (-) 1350 WP_067062086.1 sensor histidine kinase Regulator
  A0O21_RS04750 (A0O21_04755) ciaR 1019266..1019940 (-) 675 WP_067062089.1 response regulator transcription factor Regulator
  A0O21_RS04755 (A0O21_04760) - 1020210..1022753 (-) 2544 WP_067062093.1 M1 family metallopeptidase -
  A0O21_RS04760 (A0O21_04765) phoU 1022795..1023448 (-) 654 WP_067062096.1 phosphate signaling complex protein PhoU -
  A0O21_RS04765 (A0O21_04770) pstB 1023458..1024216 (-) 759 WP_067062099.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50101.14 Da        Isoelectric Point: 5.3677

>NTDB_id=173351 A0O21_RS04745 WP_067062086.1 1017927..1019276(-) (ciaH) [Streptococcus pantholopis strain TA 26]
MLSKLRRKVRSGDFSFFIHFFSVFTGIFLVMTVIILQVMRVGVYSSVDSNLQGAVANADAYVSMTMSRTLLDELEEAFAD
DSPSSENPSSEKNSSKSDFKLKPGTEMAANTSYIVYDSDGSILNNLNTFSGLQTLKLDSDKLGQVKEVAIENYSGHNEKY
HLITVAVSSIDYPEAAYLTIAINTTQLGDANSRYIKIIVVVMVIFWIISVLASVYLAKWSRKPILENYEKQKAFVENASH
ELRTPLAVLQNRLESLFRKPESTILENSENIASSLDEVRSMRLLTTNLLNLARRDDGLTPEIQELAPAFFDDLFDNYSLI
AEENQKDFTGINELTKAVKSDKPLLRQLLTILFDNAIKYTGQDGKIVLTVKQSPDKHLLIQIADNGPGISDDDKTKIFDR
FYRVDKARTRQSGGFGLGLSLAKQIVDALKGTITVKDNPPQGTVFEVKL

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=173351 A0O21_RS04745 WP_067062086.1 1017927..1019276(-) (ciaH) [Streptococcus pantholopis strain TA 26]
ATGCTGAGTAAATTAAGAAGGAAAGTAAGGTCCGGGGATTTTTCTTTCTTTATTCATTTCTTTTCTGTATTTACAGGGAT
CTTTCTGGTAATGACTGTTATCATCTTACAGGTTATGCGTGTGGGCGTTTATTCTTCTGTGGACAGCAATTTGCAGGGCG
CAGTGGCTAATGCAGATGCCTATGTGTCGATGACGATGTCACGGACCCTCTTAGACGAACTGGAGGAGGCTTTTGCGGAT
GATTCCCCTTCCTCAGAAAATCCTTCTTCGGAGAAAAACAGCAGCAAGAGCGATTTTAAACTGAAACCTGGAACGGAAAT
GGCTGCCAATACAAGCTATATTGTTTATGACAGTGACGGTTCTATTTTAAACAACCTCAATACATTTTCCGGCCTGCAGA
CTTTAAAACTCGACAGCGATAAGCTGGGGCAGGTGAAAGAGGTAGCAATTGAAAATTATTCTGGACATAATGAAAAATAC
CATCTTATCACAGTAGCTGTATCCAGCATAGACTATCCTGAAGCAGCTTATCTTACAATAGCCATTAATACGACGCAGCT
GGGAGATGCCAACTCACGCTATATCAAAATTATTGTTGTTGTCATGGTCATTTTTTGGATTATTTCTGTTTTAGCCAGTG
TGTATCTGGCTAAATGGAGCCGCAAGCCGATTTTAGAAAATTATGAGAAGCAAAAAGCTTTTGTTGAAAACGCCAGCCAT
GAACTGCGAACCCCGCTTGCTGTCCTGCAGAACCGTTTAGAAAGTTTGTTTAGGAAACCTGAATCGACCATTCTTGAAAA
CAGTGAGAACATCGCTTCAAGCCTTGACGAAGTTCGCAGCATGCGGCTTTTAACGACTAATCTCCTGAATTTAGCACGCA
GAGATGATGGGCTGACTCCTGAAATTCAAGAATTAGCCCCTGCTTTTTTCGATGATCTTTTTGATAATTACAGTTTAATC
GCTGAGGAAAATCAAAAAGACTTTACCGGTATCAATGAATTAACCAAGGCAGTAAAATCAGATAAACCTCTTTTGAGGCA
GCTTCTGACCATTTTATTTGATAATGCAATTAAGTATACTGGTCAAGACGGCAAAATTGTTCTTACCGTAAAACAGAGCC
CTGATAAGCACTTGCTGATTCAGATTGCTGATAACGGTCCGGGAATTAGTGATGACGATAAAACGAAAATTTTCGACCGG
TTTTACCGTGTAGATAAGGCAAGAACACGGCAAAGCGGCGGTTTTGGCCTGGGGCTCTCTTTAGCTAAACAGATTGTTGA
TGCACTTAAAGGGACAATTACAGTAAAAGACAATCCGCCGCAGGGTACTGTTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(341-449)

His Kinase A (phospho-acceptor) domain (HisKA)

(232-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q7E8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.243

100

0.592
  ciaH Streptococcus pneumoniae Rx1

51.435

100

0.519
  ciaH Streptococcus pneumoniae D39

51.435

100

0.519
  ciaH Streptococcus pneumoniae R6

51.435

100

0.519
  ciaH Streptococcus pneumoniae TIGR4

51.435

100

0.519

Multiple sequence alignment