Detailed information NTG0172637

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: A0E46_RS00410
• Genome accession: NZ_CP014610
• Coordinates: 71576..73723 (-)
• Length: 715 a.a.
• NCBI ID: WP_038534111.1
• Uniprot ID: -
• Organism: Leuconostoc mesenteroides subsp. mesenteroides strain BD3749
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 66576..78723

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A0E46_RS00395	-	67771..68358 (+)	588	WP_002815470.1	helix-turn-helix domain-containing protein	-
A0E46_RS00400	-	68416..69153 (+)	738	WP_002815471.1	SDR family NAD(P)-dependent oxidoreductase	-
A0E46_RS10130	-	69269..69394 (+)	126	WP_011679061.1	putative metal homeostasis protein	-
A0E46_RS00405	-	70209..71558 (-)	1350	WP_025267654.1	bacteriocin secretion accessory protein	-
A0E46_RS00410	comA	71576..73723 (-)	2148	WP_038534111.1	peptide cleavage/export ABC transporter	Regulator
A0E46_RS09915	-	73954..74130 (+)	177	WP_010287032.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A0E46_RS09920	-	74161..74322 (+)	162	WP_010287029.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A0E46_RS09925	-	74781..74918 (+)	138	WP_071951754.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A0E46_RS00420	-	74933..75112 (+)	180	WP_010287277.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A0E46_RS09930	-	75274..75450 (+)	177	WP_010287275.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A0E46_RS10135	-	75713..75883 (+)	171	WP_011679066.1	hypothetical protein	-
A0E46_RS00425	-	75889..76101 (+)	213	WP_025267657.1	hypothetical protein	-
A0E46_RS00430	-	76374..77099 (-)	726	WP_011679068.1	response regulator transcription factor	-
A0E46_RS00435	-	77105..78415 (-)	1311	WP_061514751.1	sensor histidine kinase	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80367.32 Da
• Isoelectric Point: 9.1336

>NTDB_id=172637 A0E46_RS00410 WP_038534111.1 71576..73723(-) (comA) [Leuconostoc mesenteroides subsp. mesenteroides strain BD3749]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIRERCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFDMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVAKTAMTLQEFSKEWTGVALFMSPSPRYKPFKENKNSILSFLPIIS
RQKGLIANIVVASLLVTLISIAGSYYMQLVIDAYIPSAMSNTLTVVSLGLIATYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKKSFAHQKSEAIQNSIKQATQLII
NVLVLWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NIIVDDVSYQYGYQKNILHHFSIKIPFGEKIALVGVSGSGKSTLAKLLVHFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHSVELADIKDDIENMPQSYQTEISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=172637 A0E46_RS00410 WP_038534111.1 71576..73723(-) (comA) [Leuconostoc mesenteroides subsp. mesenteroides strain BD3749]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGTGAACGCTGTCAAACATCCTTATCGGGTACAACGGCGCTAGGATTAGTGA
AGGCCGCTGAATCATTCAATATGGATGTCCGTCCTATTCAAGCTGACCTTACCTTATTCGACATGAAAGATTTACCTCTG
CCGTTCATCGCTCATGTTGAGAAAAAAGGTCAATATTTGCATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
CATTGCAGATCCAGATCCAACAGTTGCTAAAACCGCAATGACGTTACAAGAATTCTCTAAAGAGTGGACTGGTGTAGCAT
TGTTCATGTCGCCTTCACCCAGATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTCTGCCAATTATTAGT
CGACAAAAAGGATTAATTGCTAATATTGTCGTCGCTTCTTTGCTAGTCACTTTAATTAGTATCGCTGGCTCTTATTATAT
GCAACTAGTGATTGATGCTTATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGACTCATTGCCACCT
ATGTGTTACAACAGCTACTTAGTTTTGCTCGCACCTATCTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGGCACTTGTTCGAACTACCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTAACGCGTTT
TAATGACGCCAACACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGGAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTACTATCTCTAATCTCTTTTCCTATCTACTTCTTGATTGTC
TATTGTTTCATGAAGCCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACGCTGAGCTCATCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACGAGCTACCAAAAAATTGATCGTGAATTTGTCG
ATTATTTAAAAAAATCCTTTGCCCATCAAAAAAGCGAAGCCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTGCTCGTTTTATGGTTGGGTGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACCTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAGTTTAAAAAATCAGAATCACAAGAGCTTCATCATAACAACCCTCAT
AACATTATAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATCCCCTT
TGGTGAAAAAATTGCTCTGGTCGGTGTTAGCGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTCATTTTATATCTC
CTAGTGCTGGCAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGACAAAATTTAAGGCAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAATTTAACACTAGGTGCTCGTGAAAACACAACACAAGA
AGACATCCTACATTCTGTTGAGCTTGCTGACATTAAAGATGACATCGAAAATATGCCACAAAGTTATCAAACCGAAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
AACAATCATTTTTATTGCACATCGCCTGACTATTGCTGAAAAAGTCCAACGCGTTATTCTGCTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (168-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	59.944	99.86	0.599
comA	Streptococcus mitis NCTC 12261	58.146	99.58	0.579
comA	Streptococcus mitis SK321	57.865	99.58	0.576
comA	Streptococcus pneumoniae Rx1	57.584	99.58	0.573
comA	Streptococcus pneumoniae D39	57.584	99.58	0.573
comA	Streptococcus pneumoniae R6	57.584	99.58	0.573
comA	Streptococcus pneumoniae TIGR4	57.303	99.58	0.571
comA/nlmT	Streptococcus mutans UA159	54.29	99.441	0.54