Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   AXE83_RS08090 Genome accession   NZ_CP014264
Coordinates   1728885..1730771 (-) Length   628 a.a.
NCBI ID   WP_060956082.1    Uniprot ID   A0A0X8JZ40
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1723885..1735771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS08070 (AXE83_08070) - 1724948..1726222 (-) 1275 WP_060956080.1 hydroxymethylglutaryl-CoA reductase, degradative -
  AXE83_RS08075 (AXE83_08075) - 1726222..1727394 (-) 1173 WP_060956081.1 hydroxymethylglutaryl-CoA synthase -
  AXE83_RS08080 (AXE83_08080) - 1727571..1728020 (-) 450 WP_049503410.1 threonine/serine exporter family protein -
  AXE83_RS08085 (AXE83_08085) - 1728022..1728780 (-) 759 WP_049549274.1 threonine/serine exporter family protein -
  AXE83_RS08090 (AXE83_08090) stkP 1728885..1730771 (-) 1887 WP_060956082.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  AXE83_RS08095 (AXE83_08095) - 1730768..1731508 (-) 741 WP_060956083.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  AXE83_RS08100 (AXE83_08100) rsmB 1731524..1732837 (-) 1314 WP_060956395.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  AXE83_RS08105 (AXE83_08105) fmt 1732830..1733765 (-) 936 WP_060956084.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 628 a.a.        Molecular weight: 69185.84 Da        Isoelectric Point: 8.6576

>NTDB_id=170014 AXE83_RS08090 WP_060956082.1 1728885..1730771(-) (stkP) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTKGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYQSVSEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVSQTTLTSIPKVQPQTDSHQAT
KASPEVSAKKSVEKPVKKRRFKARYLVLLASFVLVAASLVWILSRTPATIDIPNVAGQTVAEAKETLKKANFEVGDEKTE
ASETVEEGRVIRTDPEAGSNRKEGSKINLIISTGKQSFKIGNYIGKKSTDVIAELKEKKVPENLIKIEEEESSESEPGVI
LKQSLSEGTTYDLTKATSIVLTVAKKKKVTTVTMPNYVGYSLEFAKNNLKSLGISEDRIEIKEVEIAQEGIKEGEIAKQS
PAPDEKLDLSNPIVKLYIYKPKKNSPPISQPSSEQNSGQTDTTNPTNPTQGNHPTTPTQDGTGSQRNQ

Nucleotide


Download         Length: 1887 bp        

>NTDB_id=170014 AXE83_RS08090 WP_060956082.1 1728885..1730771(-) (stkP) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTATCAAACAAATTGGCCGTGGGGGTATGGCAGATGTCTA
CCTGGCCAAGGATTTGATTTTAGACGGGGAAGAGGTAGCTGTAAAGGTCCTGAGGACTAACTACCAGACTGACCCGATTG
CTGTTGCGCGTTTTCAGCGTGAAGCGCGTGCAATGGCTGACTTAGATCATCCCCATATCGTTCGGATAACGGATATCGGT
GAAGAGGACGGTCAACAGTACCTGGCTATGGAATATGTAGCTGGTCTTGATCTCAAGCGCTATATCAAGGAACACTATCC
CCTCTCAAATGAAGAGGCTGTCCGTATCATGGGTCAGATTCTCTTAGCGATGCGCTTGGCGCACACTAAAGGTATTGTCC
ATCGTGACTTAAAGCCTCAAAATATTCTTTTAACTCCGGATGGGACGGCTAAGGTAACGGACTTTGGGATTGCCGTAGCC
TTTGCAGAGACCAGTCTGACTCAGACCAACTCTATGTTGGGTTCTGTTCACTACTTGTCACCTGAGCAGGCTCGTGGTTC
TAAAGCAACGTTCCAAAGTGACATCTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGGCATATCCCTTATGATG
GCGATAGTGCAGTAACCATCGCTCTCCAGCATTTTCAAAAACCTCTTCCTTCGGTCATAGCTGAAAATCCATCTGTTCCC
CAAGCTTTGGAGAATGTGGTCATCAAAGCAACTGCTAAAAAGCTAACAGATCGATACCAGTCGGTTTCAGAGATGTATGT
TGATTTATCTAGCAGTCTATCTTATAACCGCAGAAATGAACCTAAACTTGTTTTTGATGATGCTACTAAGGCGGACACAA
AGACATTGCCAAAGGTTTCTCAAACAACCTTGACCTCTATTCCTAAGGTTCAACCACAGACAGATAGCCATCAGGCAACT
AAAGCTAGCCCAGAAGTAAGCGCTAAAAAATCTGTGGAAAAACCAGTGAAAAAACGTCGTTTTAAAGCACGCTATCTGGT
TCTACTAGCAAGTTTCGTACTGGTTGCGGCTTCTCTAGTATGGATTTTATCCAGAACACCAGCTACCATCGATATTCCAA
ATGTAGCAGGTCAAACAGTTGCTGAAGCTAAGGAAACCTTGAAAAAAGCCAACTTTGAAGTTGGTGATGAGAAAACGGAA
GCTAGTGAAACAGTCGAGGAAGGACGAGTGATTCGGACAGATCCTGAGGCAGGTAGTAACCGAAAAGAGGGAAGTAAGAT
TAATCTGATTATTTCAACTGGTAAGCAATCCTTTAAGATTGGTAATTACATTGGTAAGAAGTCTACAGATGTCATTGCTG
AGTTGAAGGAGAAAAAAGTTCCCGAAAATCTGATTAAGATTGAGGAGGAAGAGTCCAGTGAATCGGAACCAGGTGTGATT
TTGAAACAGAGTTTATCTGAAGGTACGACCTATGATCTTACTAAGGCTACTTCCATCGTCTTGACAGTTGCTAAAAAGAA
AAAGGTTACAACTGTGACCATGCCAAACTATGTTGGATATAGTCTTGAATTTGCAAAAAATAATCTCAAAAGTTTAGGTA
TTAGTGAAGATAGAATTGAAATTAAAGAAGTGGAGATAGCACAAGAAGGAATTAAAGAAGGTGAGATTGCCAAACAAAGT
CCCGCACCCGATGAAAAACTTGATTTAAGCAATCCGATAGTTAAACTCTATATTTATAAACCTAAAAAAAATTCACCACC
AATTAGTCAACCTTCGTCAGAACAAAATTCTGGTCAAACTGACACAACAAACCCTACAAACCCTACGCAGGGTAACCATC
CAACAACACCTACACAAGATGGAACTGGAAGTCAACGAAATCAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(439-505)

PASTA domain (PASTA)

(512-580)

PASTA domain (PASTA)

(371-433)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JZ40

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

80.769

91.083

0.736
  stkP Streptococcus pneumoniae D39

80.42

91.083

0.732
  stkP Streptococcus pneumoniae R6

80.42

91.083

0.732
  stkP Streptococcus pneumoniae Rx1

80.245

91.083

0.731
  pknB Streptococcus mutans UA159

57.982

86.783

0.503
  stkP/pknB Streptococcus salivarius strain HSISS4

57.169

86.624

0.495

Multiple sequence alignment