Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   AXE83_RS04940 Genome accession   NZ_CP014264
Coordinates   1046958..1047662 (+) Length   234 a.a.
NCBI ID   WP_060955646.1    Uniprot ID   A0A0X8JY01
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041958..1052662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS10975 (AXE83_04920) - 1042590..1042754 (+) 165 WP_049502767.1 hypothetical protein -
  AXE83_RS04925 (AXE83_04925) - 1042790..1043260 (-) 471 WP_001030117.1 arginine repressor -
  AXE83_RS04930 (AXE83_04930) - 1043211..1045550 (-) 2340 WP_060955644.1 Xaa-Pro dipeptidyl-peptidase -
  AXE83_RS04935 (AXE83_04935) mutY 1045730..1046893 (+) 1164 WP_060955645.1 A/G-specific adenine glycosylase -
  AXE83_RS04940 (AXE83_04940) micA 1046958..1047662 (+) 705 WP_060955646.1 response regulator YycF Regulator
  AXE83_RS04945 (AXE83_04945) micB 1047655..1049004 (+) 1350 WP_060955647.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AXE83_RS04950 (AXE83_04950) vicX 1049006..1049815 (+) 810 WP_060955648.1 MBL fold metallo-hydrolase Regulator
  AXE83_RS04955 (AXE83_04955) - 1049853..1050200 (-) 348 WP_060955649.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  AXE83_RS04960 (AXE83_04960) - 1050459..1052177 (-) 1719 WP_060955650.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26923.71 Da        Isoelectric Point: 4.6741

>NTDB_id=169998 AXE83_RS04940 WP_060955646.1 1046958..1047662(+) (micA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTELASADNQEPETKLQSLQIGDLEILPDAYVAKKYGEELDLT
HREFELLHHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=169998 AXE83_RS04940 WP_060955646.1 1046958..1047662(+) (micA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGAAAAAAATACTAATTGTAGATGATGAAAAACCCATCTCAGATATTATAAAATTTAATATGACCAAGGAAGGTTATGA
AGTTGTAACTGCTTTCAATGGTCGTGAAGCTCTTGAACAATTTGAAGCTGAGCAACCAGATATTATTATCTTGGATTTGA
TGCTTCCAGAGATTGATGGACTTGAGGTCGCAAAAACTATTCGTAAGACAAGTAGTGTTCCAATTATCATGCTTTCAGCT
AAAGACAGCGAGTTTGATAAGGTTATCGGTCTTGAACTTGGGGCGGATGACTATGTAACTAAGCCCTTTTCAAATCGTGA
ACTACAGGCCCGTGTTAAGGCCTTACTTCGCCGTACAGAGCTAGCTTCTGCTGATAACCAAGAGCCTGAAACGAAACTAC
AAAGTCTGCAAATCGGTGACTTGGAGATCCTCCCAGATGCTTATGTCGCTAAGAAATATGGTGAAGAGTTAGACCTAACC
CACCGCGAATTCGAACTCTTACATCATTTAGCTTCTCATATTGGTCAAGTGATCACCCGTGAGCACCTCCTTGAGACTGT
TTGGGGTTATGACTACTTTGGGGATGTCCGTACAGTAGACGTAACCATTAGACGCTTGCGCGAGAAGATTGAAGATACAC
CAAGTAGACCTGAATACATCCTAACTCGTCGTGGAGTGGGATATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JY01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.275

99.573

0.919
  vicR Streptococcus mutans UA159

79.574

100

0.799
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.217

98.291

0.444
  covR Streptococcus salivarius strain HSISS4

44.348

98.291

0.436
  scnR Streptococcus mutans UA159

37.931

99.145

0.376

Multiple sequence alignment