Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   BJK09_RS06235 Genome accession   NZ_CP017601
Coordinates   1364829..1365506 (-) Length   225 a.a.
NCBI ID   WP_011213604.1    Uniprot ID   -
Organism   Legionella pneumophila strain D6026     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1359829..1370506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJK09_RS06210 (BJK09_06110) ruvC 1359992..1360516 (+) 525 WP_027226814.1 crossover junction endodeoxyribonuclease RuvC -
  BJK09_RS06215 (BJK09_06115) ruvA 1360513..1361112 (+) 600 WP_027226815.1 Holliday junction branch migration protein RuvA Machinery gene
  BJK09_RS06220 (BJK09_06120) - 1361171..1361491 (+) 321 WP_027226816.1 hypothetical protein -
  BJK09_RS06225 (BJK09_06125) lem8 1361569..1363128 (-) 1560 WP_027226817.1 Dot/Icm T4SS effector Lem8 -
  BJK09_RS06230 (BJK09_06130) - 1363417..1364832 (-) 1416 WP_027226818.1 ATP-binding protein -
  BJK09_RS06235 (BJK09_06135) ciaR 1364829..1365506 (-) 678 WP_011213604.1 response regulator Regulator
  BJK09_RS06240 (BJK09_06140) - 1365567..1366112 (-) 546 WP_027221489.1 septation protein A -
  BJK09_RS06245 (BJK09_06145) - 1366356..1367795 (-) 1440 WP_027226819.1 lytic transglycosylase -
  BJK09_RS06250 (BJK09_06150) gloB 1367909..1368673 (-) 765 WP_027226820.1 hydroxyacylglutathione hydrolase -
  BJK09_RS06255 (BJK09_06155) - 1368677..1369525 (-) 849 WP_027226821.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  BJK09_RS06260 (BJK09_06160) - 1369664..1369873 (+) 210 WP_011213609.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25151.74 Da        Isoelectric Point: 4.9981

>NTDB_id=169418 BJK09_RS06235 WP_011213604.1 1364829..1365506(-) (ciaR) [Legionella pneumophila strain D6026]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=169418 BJK09_RS06235 WP_011213604.1 1364829..1365506(-) (ciaR) [Legionella pneumophila strain D6026]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGTGATGCAGTAAAAGCCGGATTGACACAATTTGGGTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCGCGAGCAGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTACAAAACATCAGACATGATGGAAATTCCACACCTGTCATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGAGTAAAAGGTTTAGATAGTGGCGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCCTTGGTAAGGCGCTCTCAGGGTAGAGCTGATTCAGTGTTGCAATATAAAAATATTACCC
TTGATCCAGCCGCTCATTCTGTATTCGTGGATGATGTTCTCGTCAATGTTCCAAGAAGAGAATTCGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGTCAAGTCTTATCTCGAGAACAATTAATGCAGAGTATTTATGGTTGGGAAGAAGACGTGGACAG
CAATGCTCTTGAGGTTCATATCCATAATTTACGTAAAAAACTTAATGCAAACTTTATCCGCACTATTCGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-215)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae D39

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae R6

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae TIGR4

38.356

97.333

0.373
  ciaR Streptococcus mutans UA159

37.9

97.333

0.369
  micA Streptococcus pneumoniae Cp1015

35.345

100

0.364