Detailed information NTG0169338

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: AWJ15_RS07955
• Genome accession: NZ_CP014201
• Coordinates: 1594099..1596291 (-)
• Length: 730 a.a.
• NCBI ID: WP_077069577.1
• Uniprot ID: -
• Organism: Lacticaseibacillus rhamnosus strain BFE5264
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1589099..1601291

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AWJ15_RS07930 (AWJ15_07300)	-	1589319..1590401 (+)	1083	Protein_1448	aldo/keto reductase	-
AWJ15_RS07940 (AWJ15_07310)	-	1590701..1592056 (-)	1356	WP_005686876.1	threonine/serine exporter ThrE family protein	-
AWJ15_RS07945 (AWJ15_07315)	-	1592236..1592646 (-)	411	WP_005686874.1	hypothetical protein	-
AWJ15_RS07950 (AWJ15_07320)	-	1592707..1594086 (-)	1380	WP_031547267.1	bacteriocin secretion accessory protein	-
AWJ15_RS07955 (AWJ15_07325)	comA	1594099..1596291 (-)	2193	WP_077069577.1	peptide cleavage/export ABC transporter	Regulator
AWJ15_RS17085	-	1596567..1596719 (-)	153	WP_005686869.1	bacteriocin-like peptide, LSEI_2386 family	-
AWJ15_RS07960 (AWJ15_07330)	-	1596906..1598201 (+)	1296	WP_005686867.1	GHKL domain-containing protein	-
AWJ15_RS07965 (AWJ15_07335)	-	1598206..1598982 (+)	777	WP_005686865.1	response regulator transcription factor	-
AWJ15_RS07985 (AWJ15_07345)	-	1600096..1600341 (-)	246	WP_005686864.1	hypothetical protein	-
AWJ15_RS07990 (AWJ15_07350)	-	1600591..1600890 (-)	300	WP_031546828.1	bacteriocin immunity protein	-
AWJ15_RS07995 (AWJ15_07355)	-	1601068..1601226 (-)	159	WP_005686855.1	class IIb bacteriocin, lactobin A/cerein 7B family	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81537.81 Da
• Isoelectric Point: 7.2454

>NTDB_id=169338 AWJ15_RS07955 WP_077069577.1 1594099..1596291(-) (comA) [Lacticaseibacillus rhamnosus strain BFE5264]
MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSLAHLRELAKTNQDGTTALGIVRAAEALAFETKPVQA
NMQLFDLEDVPYPFIAHVLKRGELLHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKED
KGSLFAFVPMLAKQKSIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGLLVAYLLQAVLTYGQNFLM
AVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFADANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLV
SLIAVPCYLVIVFAFQRPFDRLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQL
QQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFKE
QRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNVNLEVPENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPV
KDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDHATLLAQ
DGYYARLVHE

Nucleotide

• Length: 2193 bp

>NTDB_id=169338 AWJ15_RS07955 WP_077069577.1 1594099..1596291(-) (comA) [Lacticaseibacillus rhamnosus strain BFE5264]
ATGGTTAAATACACCCCAAAACTAGGCCAGATCACCTACTACAAACGTTTCTACACCGCACAAGTTGACGAGCGTGACTG
TGGTGTGGCTGCGTTAAACATGCTGCTTAAATACAATGGGTCGGACTATTCGTTAGCCCACTTGCGCGAGTTAGCGAAGA
CAAATCAGGATGGCACGACGGCTTTGGGAATCGTTCGGGCCGCTGAAGCACTAGCGTTTGAGACGAAACCGGTGCAGGCG
AATATGCAGTTGTTTGATCTTGAGGATGTGCCTTATCCGTTTATTGCCCATGTGCTGAAGCGCGGTGAATTGCTTCATTA
CTATGTTGTTTTTAAAGCAACGCGCACGAGTATTCTGATTGGCGATCCTGACCCGTCAGTGCGCATGACCTGGCTTTCGC
GAGAGGTGTTTGAAAAAGAATGGTCGGGTGTGGCCATCTTTATTGCACCGGCGCCGCAGTATCAGCCGCGTAAGGAGGAC
AAAGGCAGTTTGTTTGCGTTTGTACCCATGCTGGCTAAGCAAAAAAGTATTATCGCGAACATTATTCTGGCCGCGGTATT
GATTACGGTCATTAGTATCGTTGGGTCGTATTTTTTGCAGTCTATTATTGATACGTATATACCGAATGCCATGCGGACGA
CGATGGGGATGATTGCTAGTGGCCTTTTGGTGGCTTACTTGCTGCAAGCTGTGTTGACTTATGGCCAGAATTTTTTGATG
GCGGTGTTGGGGCAGCGGCTTGCGATTGATGTCATTTTAGGGTATGTGCGCCACTTATATGAATTGCCGATGTCGTTTTT
TTCAACTCGGCGGACCGGAGAGATTGTGTCGCGGTTTGCGGATGCCAATAAAATTATTGACGCGCTGGCGAATACGATTA
TGACGTTGTTTTTGGATGTCTGGATTGTCCTAATATTAGGCATTGTTCTAGGGATCCAAAATGGGACTTTGTTTTTAGTG
TCATTGATTGCCGTGCCGTGTTATTTGGTGATTGTTTTTGCATTTCAGCGGCCGTTTGATCGGTTGAACCAAGAGACGAT
GGAAAGTAACGCAATCTTGAGTTCATCGATTATTGAAGATTTGAATGGCATTGAAACCATCAAGTCCCTGACCGGCGAAC
GAGTTAGCTATGAACGGGTTGATCGGGAATTTCTAACCTATCTGAAGAAATCGTTTAGTTACACCAAGGCAGATCAATTA
CAGCAAGCGATTAAAGGTCTGTTGAAGCTGGCGTTGAACGTTGTGGTGTTGTGGATTGGGGCAAGTTTGGTGATTGCCAA
TCGGATGAGCTTGGGGCAGATGCTGACCTTTAATGCACTGCTGTCATACTTTACGAATCCGCTTGAAAGCATCATCAACC
TACAGCCAAAGTTACAAATGGCGCGGGTTGCTAACAATCGCCTGAATGAAGTTTATCTGGTCGAATCGGAATTCAAAGAA
CAGCGGCACTTGACGGAGCGGCATTTAATCGAAGGTCCGATACGCGTTCGGGATGTCTCGTTTAAATATGGTTTTGGCCA
AGATGTATTGAAAAACGTCAACCTTGAAGTGCCGGAAAATGCTAAATATACCATTGTTGGCATGAGCGGTTCTGGTAAGT
CGACATTAGCAAAATTATTAGTTGGCTTTTACCCGGTTGATGCCGACAAAGGAACCATCACGTTTAATGGCATTCCGGTC
AAAGACATTAACCTGACAACATTACGGCAATATATTGAATATGTACCTCAGGATCCGTTTATTTTTTCGGGCACGGTGTT
GGAGAATTTGACGTTAGGTAGCCGTTCGGATGTTTCGGAACAAGATTTGACGCAGGCGTGTTTGGCTGCGGAAATTGCCG
CAGACATCGCAAACTTACCGCAGCAGTGGCAGACCAAATTGTCAGAAAGCGGCAGTATTTTATCAGGCGGTCAGAAGCAG
CGGCTGGCGATTGCACGGGCCTTGTTGTCACCGGCAAAAGTACTGATTTTTGACGAATCGACCAGCAGTCTGGATACCAT
TACAGAGCGAAAAATTGTCGATCGCTTGCTGGCAATGACGGATCGGACCATTATTTTTGTTGCCCATCGCTTAACTATTG
CGGCTAAAACCGAACAAATTGTGGTGATGGATCATGGCAAAATTGTGGAACAAGGTGACCATGCAACGTTGTTAGCCCAA
GACGGTTATTACGCGCGCCTGGTTCATGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (18-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae D39	58.042	97.945	0.568
comA	Streptococcus pneumoniae R6	58.042	97.945	0.568
comA	Streptococcus pneumoniae Rx1	58.042	97.945	0.568
comA	Streptococcus pneumoniae TIGR4	57.622	97.945	0.564
comA	Streptococcus mitis NCTC 12261	57.622	97.945	0.564
comA	Streptococcus mitis SK321	57.483	97.945	0.563
comA	Streptococcus gordonii str. Challis substr. CH1	56.467	98.493	0.556
comA/nlmT	Streptococcus mutans UA159	53.686	98.493	0.529