Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   A4W85_RS00405 Genome accession   NZ_CP017570
Coordinates   79352..80620 (+) Length   422 a.a.
NCBI ID   WP_056946885.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain TMW 1.578     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 74352..85620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4W85_RS00390 (A4W85_00385) - 76220..77551 (+) 1332 WP_251945048.1 YycH family regulatory protein -
  A4W85_RS00395 (A4W85_00390) - 77556..78377 (+) 822 WP_011373793.1 two-component system regulatory protein YycI -
  A4W85_RS00400 (A4W85_00395) vicX 78412..79218 (+) 807 WP_011373794.1 MBL fold metallo-hydrolase Regulator
  A4W85_RS00405 (A4W85_00400) htrA 79352..80620 (+) 1269 WP_056946885.1 S1C family serine protease Regulator
  A4W85_RS00410 (A4W85_00405) rlmH 81156..81635 (+) 480 WP_011373797.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A4W85_RS00415 (A4W85_00410) - 81775..82422 (+) 648 WP_076981366.1 hypothetical protein -
  A4W85_RS00420 (A4W85_00415) add 82479..83504 (-) 1026 WP_016264371.1 adenosine deaminase -
  A4W85_RS00425 (A4W85_00420) - 83674..85017 (+) 1344 WP_011373800.1 NCS2 family permease -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 43112.23 Da        Isoelectric Point: 9.2635

>NTDB_id=169319 A4W85_RS00405 WP_056946885.1 79352..80620(+) (htrA) [Latilactobacillus sakei strain TMW 1.578]
MNQNSGLMKTAIVVVISALIGGGAAYAGFSRLGNSANDVTTATQTPTKAGATKISNIKVNSSSQTTTAFQKVNTSVVSVV
NLQKQQQSTGDLSSLFGSGSTDSNSSSSKSSSSDLEESSEGSGLIYEKKDGKAYIVTNNHVVAGSDKIEVILSDGTKLEA
SLVGTDAVSDLAVLKINGTKVKKTATFGDSDSIKAGESVLAIGSPLGSEYATSVTQGIISAKKRTIDVTDETTGQTTGQA
TVIQTDTAINPGNSGGPLVNMAGQVIGINSMKLASNGETSVEGMGFAIPSNEVVKIINQLVANGKVVRPALGISVIDLTN
ISSTQQSSVLKLPSSVNSGVVVASVTSNSVAKKAGISKYDVIVGLGGKTVSSVADLHTILYSYAMNSTTEIQYYHNGSLK
KANVKLTQAASSDSTTTTKQTN

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=169319 A4W85_RS00405 WP_056946885.1 79352..80620(+) (htrA) [Latilactobacillus sakei strain TMW 1.578]
ATGAATCAAAATTCAGGATTAATGAAAACAGCGATTGTTGTGGTTATTTCAGCGTTGATTGGTGGTGGCGCAGCCTATGC
CGGTTTTTCTCGACTCGGCAATTCGGCCAATGACGTCACGACTGCAACGCAGACGCCTACTAAAGCGGGGGCAACTAAGA
TTAGTAACATCAAAGTGAACTCATCATCACAAACGACAACCGCCTTCCAAAAGGTTAATACATCAGTTGTATCCGTTGTG
AACTTACAAAAACAACAACAATCAACCGGTGACCTGAGTTCATTATTTGGTTCAGGGAGCACTGACAGCAATAGCAGTTC
TTCTAAGAGCAGTAGCAGTGATTTAGAAGAATCCAGTGAAGGTTCAGGTTTAATCTACGAGAAAAAAGACGGCAAAGCTT
ACATCGTGACGAATAATCACGTGGTTGCTGGTTCTGATAAAATCGAAGTCATTTTGAGTGATGGCACAAAATTGGAAGCT
AGTTTAGTTGGGACAGATGCTGTTTCTGATTTGGCTGTCTTAAAAATTAACGGGACTAAAGTGAAGAAGACGGCAACGTT
TGGTGATTCAGATAGTATCAAAGCTGGTGAATCAGTTCTTGCGATCGGCTCACCATTGGGCTCAGAATACGCAACTTCTG
TCACACAAGGGATTATTTCTGCTAAGAAACGGACCATTGATGTGACAGACGAAACAACCGGCCAAACAACTGGTCAAGCA
ACTGTTATTCAAACTGATACAGCGATTAACCCTGGGAATTCAGGTGGCCCATTAGTCAACATGGCTGGTCAAGTCATTGG
GATTAATTCAATGAAATTAGCTTCAAATGGTGAAACGTCTGTTGAAGGGATGGGCTTTGCTATTCCAAGTAACGAAGTCG
TTAAAATTATTAACCAATTGGTGGCTAACGGGAAAGTGGTTAGACCAGCACTTGGGATTAGTGTGATTGATTTAACCAAT
ATTTCATCAACACAACAATCTTCAGTACTAAAATTACCATCATCCGTTAACAGCGGGGTAGTAGTGGCCTCAGTAACAAG
CAATTCAGTTGCTAAGAAGGCTGGTATCAGTAAGTATGATGTGATTGTCGGCTTAGGCGGCAAGACGGTTTCAAGTGTGG
CAGACTTACACACAATTCTATATAGTTACGCAATGAACAGCACAACTGAAATTCAGTACTATCATAATGGCAGCTTGAAA
AAAGCGAATGTTAAACTCACACAAGCAGCTTCATCAGATAGTACGACAACAACTAAACAAACGAACTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(121-268)

Peptidase family M50 (Peptidase_M50)

(256-413)

PDZ domain (PDZ_2)

(309-406)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

45.074

96.209

0.434
  htrA Streptococcus gordonii str. Challis substr. CH1

43.237

98.104

0.424
  htrA Streptococcus mutans UA159

46.237

88.152

0.408
  htrA Streptococcus pneumoniae TIGR4

49.284

82.701

0.408
  htrA Streptococcus pneumoniae R6

49.284

82.701

0.408
  htrA Streptococcus pneumoniae Rx1

49.284

82.701

0.408
  htrA Streptococcus pneumoniae D39

49.284

82.701

0.408

Multiple sequence alignment