Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AWB63_RS01440 Genome accession   NZ_CP014144
Coordinates   280091..280780 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain JF     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 275091..285780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWB63_RS01415 (AWB63_01415) - 275324..276154 (+) 831 WP_002886584.1 energy-coupling factor transporter transmembrane component T family protein -
  AWB63_RS01420 (AWB63_01420) - 276243..276914 (-) 672 WP_014633599.1 potassium channel family protein -
  AWB63_RS01425 (AWB63_01425) - 276954..278318 (-) 1365 WP_080730925.1 TrkH family potassium uptake protein -
  AWB63_RS01430 (AWB63_01430) rsmG 278387..279100 (-) 714 WP_038675301.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  AWB63_RS01435 (AWB63_01435) - 279399..279935 (+) 537 WP_014633893.1 DUF177 domain-containing protein -
  AWB63_RS01440 (AWB63_01440) covR 280091..280780 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  AWB63_RS01445 (AWB63_01445) covS 280777..282306 (+) 1530 WP_014633896.1 HAMP domain-containing sensor histidine kinase Regulator
  AWB63_RS01450 (AWB63_01450) nrdR 282428..282907 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  AWB63_RS01455 (AWB63_01455) - 282904..284079 (+) 1176 WP_014633897.1 DnaD domain protein -
  AWB63_RS01460 (AWB63_01460) dnaI 284083..284985 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=168718 AWB63_RS01440 WP_002883757.1 280091..280780(+) (covR) [Streptococcus salivarius strain JF]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=168718 AWB63_RS01440 WP_002883757.1 280091..280780(+) (covR) [Streptococcus salivarius strain JF]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCCAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment