Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   AWB63_RS01445 Genome accession   NZ_CP014144
Coordinates   280777..282306 (+) Length   509 a.a.
NCBI ID   WP_014633896.1    Uniprot ID   A0AB33ZGE8
Organism   Streptococcus salivarius strain JF     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 275777..287306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWB63_RS01420 (AWB63_01420) - 276243..276914 (-) 672 WP_014633599.1 potassium channel family protein -
  AWB63_RS01425 (AWB63_01425) - 276954..278318 (-) 1365 WP_080730925.1 TrkH family potassium uptake protein -
  AWB63_RS01430 (AWB63_01430) rsmG 278387..279100 (-) 714 WP_038675301.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  AWB63_RS01435 (AWB63_01435) - 279399..279935 (+) 537 WP_014633893.1 DUF177 domain-containing protein -
  AWB63_RS01440 (AWB63_01440) covR 280091..280780 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  AWB63_RS01445 (AWB63_01445) covS 280777..282306 (+) 1530 WP_014633896.1 HAMP domain-containing sensor histidine kinase Regulator
  AWB63_RS01450 (AWB63_01450) nrdR 282428..282907 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  AWB63_RS01455 (AWB63_01455) - 282904..284079 (+) 1176 WP_014633897.1 DnaD domain protein -
  AWB63_RS01460 (AWB63_01460) dnaI 284083..284985 (+) 903 WP_002883792.1 primosomal protein DnaI -
  AWB63_RS01465 (AWB63_01465) der 285090..286400 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  AWB63_RS01470 (AWB63_01470) - 286465..287094 (+) 630 WP_038675302.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58085.46 Da        Isoelectric Point: 5.1853

>NTDB_id=168719 AWB63_RS01445 WP_014633896.1 280777..282306(+) (covS) [Streptococcus salivarius strain JF]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVIFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=168719 AWB63_RS01445 WP_014633896.1 280777..282306(+) (covS) [Streptococcus salivarius strain JF]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTATTTTCTCAGCCAATACACTACTTTTACAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATAGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCTGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGTGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGACTCGCCTCCAGGTATGTCCGAGGTAAACAAATTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATCTTCCATGATTTGGAATTCTA
TTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCGACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGACATGTTGGATTCTATCCGTGTCAAAGGGTCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGTTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACAACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998

Multiple sequence alignment