Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   WH25_RS09730 Genome accession   NZ_CP017295
Coordinates   2033887..2034804 (-) Length   305 a.a.
NCBI ID   WP_046164649.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2028887..2039804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS09705 (WH25_09705) - 2029026..2029343 (-) 318 WP_004188921.1 PTS sugar transporter subunit IIB -
  WH25_RS09710 (WH25_09710) - 2029557..2030750 (+) 1194 WP_046164646.1 ROK family transcriptional regulator -
  WH25_RS09715 (WH25_09715) - 2030814..2031710 (-) 897 WP_046164647.1 PEP phosphonomutase -
  WH25_RS09720 (WH25_09720) - 2031941..2032819 (-) 879 WP_046164648.1 ABC transporter permease -
  WH25_RS09725 (WH25_09725) - 2032812..2033741 (-) 930 WP_046164753.1 ABC transporter ATP-binding protein -
  WH25_RS09730 (WH25_09730) comR 2033887..2034804 (-) 918 WP_046164649.1 helix-turn-helix domain-containing protein Regulator
  WH25_RS09735 (WH25_09735) - 2034954..2036846 (-) 1893 WP_046164650.1 M13 family metallopeptidase -
  WH25_RS09740 (WH25_09740) - 2036993..2037712 (+) 720 WP_046164651.1 metal ABC transporter ATP-binding protein -
  WH25_RS09745 (WH25_09745) - 2037714..2038550 (+) 837 WP_046164652.1 metal ABC transporter permease -
  WH25_RS09750 (WH25_09750) scaA 2038577..2039509 (+) 933 WP_046164653.1 metal ABC transporter substrate-binding lipoprotein/adhesin ScaA -

Sequence

Protein


Download         Length: 305 a.a.        Molecular weight: 36127.42 Da        Isoelectric Point: 4.4286

>NTDB_id=168037 WH25_RS09730 WP_046164649.1 2033887..2034804(-) (comR) [Streptococcus gordonii strain IE35]
MEFKEELGQKIQSLREEKGLSRLAICGEEDILTTRQLQRIEKGQSLPTIATALYIAEQLEVSLDTLANRERLELPSGYLE
LKYRLEKLYHYGDGERLQQREELIEEIYRKYFDQLPEEEQLYLQIKQAKNDMVLTENIAYDQGLIDEYLDQALAKEKLTE
MDLEIIDLRLLALGLKDFDKKEFTCLLNKLLEAVADYPTSGLEKIQTRIIFAAGVLSHYQEYDLLPKILRALEELMLRRN
DFQDRVFSYALQWKIALFLENNLEKAEDNYQKVKLMLELLPEDVLKENMRLDWEQDIRRYSKIDE

Nucleotide


Download         Length: 918 bp        

>NTDB_id=168037 WH25_RS09730 WP_046164649.1 2033887..2034804(-) (comR) [Streptococcus gordonii strain IE35]
GTGGAATTCAAGGAAGAGCTAGGACAGAAAATACAATCTCTAAGAGAAGAAAAAGGCTTGAGTCGTCTGGCGATCTGTGG
GGAAGAAGATATCTTGACAACGCGGCAATTACAGCGAATTGAAAAAGGCCAGTCTCTGCCTACCATCGCAACAGCTCTCT
ATATTGCTGAGCAACTGGAAGTATCACTGGATACACTAGCAAATAGAGAGCGATTAGAGTTACCGTCTGGCTATCTTGAA
TTGAAGTATCGCTTGGAAAAGCTTTATCACTATGGCGATGGAGAGCGCCTTCAACAAAGAGAAGAGCTGATCGAGGAAAT
CTATCGAAAGTATTTCGATCAACTCCCTGAGGAAGAACAACTTTATCTTCAGATTAAGCAGGCCAAGAACGATATGGTTT
TAACGGAAAATATTGCCTATGATCAAGGCTTAATAGATGAATATCTGGATCAGGCTTTGGCCAAGGAAAAATTGACGGAA
ATGGATCTAGAAATCATTGATTTACGCCTGTTGGCGCTTGGTTTGAAAGATTTTGACAAGAAGGAGTTTACTTGTTTGCT
AAACAAGTTGCTTGAGGCGGTAGCTGATTATCCTACCAGCGGCTTGGAAAAAATCCAGACCAGAATCATTTTTGCGGCGG
GGGTCTTGTCTCATTATCAAGAATATGACCTCCTACCTAAAATATTACGAGCCCTGGAAGAGCTGATGTTGAGGCGAAAC
GACTTTCAAGATCGTGTCTTTAGCTATGCGCTTCAGTGGAAAATCGCCCTCTTCTTGGAAAATAATCTCGAAAAAGCTGA
GGACAACTATCAAAAGGTCAAGCTAATGCTAGAGCTATTGCCAGAAGATGTCCTTAAGGAGAATATGAGACTGGACTGGG
AGCAGGATATAAGACGCTATAGTAAAATTGATGAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.374

97.377

0.364

Multiple sequence alignment