Detailed information NTG0167766

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A4W88_RS00375
• Genome accession: NZ_CP017275
• Coordinates: 73461..74729 (+)
• Length: 422 a.a.
• NCBI ID: WP_056946885.1
• Uniprot ID: -
• Organism: Latilactobacillus sakei strain TMW 1.1398
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 68461..79729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4W88_RS00360 (A4W88_00355)	yycH	70329..71660 (+)	1332	WP_056946880.1	two-component system activity regulator YycH	-
A4W88_RS00365 (A4W88_00360)	-	71665..72486 (+)	822	WP_076631997.1	two-component system regulatory protein YycI	-
A4W88_RS00370 (A4W88_00365)	vicX	72521..73327 (+)	807	WP_011373794.1	MBL fold metallo-hydrolase	Regulator
A4W88_RS00375 (A4W88_00370)	htrA	73461..74729 (+)	1269	WP_056946885.1	trypsin-like peptidase domain-containing protein	Regulator
A4W88_RS00380 (A4W88_00375)	rlmH	75265..75744 (+)	480	WP_011373797.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A4W88_RS00385 (A4W88_00380)	-	75884..76531 (+)	648	WP_076981366.1	hypothetical protein	-
A4W88_RS00395 (A4W88_00395)	add	78045..79070 (-)	1026	WP_076632315.1	adenosine deaminase	-

Sequence

Protein

• Length: 422 a.a.
• Molecular weight: 43112.23 Da
• Isoelectric Point: 9.2635

>NTDB_id=167766 A4W88_RS00375 WP_056946885.1 73461..74729(+) (htrA) [Latilactobacillus sakei strain TMW 1.1398]
MNQNSGLMKTAIVVVISALIGGGAAYAGFSRLGNSANDVTTATQTPTKAGATKISNIKVNSSSQTTTAFQKVNTSVVSVV
NLQKQQQSTGDLSSLFGSGSTDSNSSSSKSSSSDLEESSEGSGLIYEKKDGKAYIVTNNHVVAGSDKIEVILSDGTKLEA
SLVGTDAVSDLAVLKINGTKVKKTATFGDSDSIKAGESVLAIGSPLGSEYATSVTQGIISAKKRTIDVTDETTGQTTGQA
TVIQTDTAINPGNSGGPLVNMAGQVIGINSMKLASNGETSVEGMGFAIPSNEVVKIINQLVANGKVVRPALGISVIDLTN
ISSTQQSSVLKLPSSVNSGVVVASVTSNSVAKKAGISKYDVIVGLGGKTVSSVADLHTILYSYAMNSTTEIQYYHNGSLK
KANVKLTQAASSDSTTTTKQTN

Nucleotide

• Length: 1269 bp

>NTDB_id=167766 A4W88_RS00375 WP_056946885.1 73461..74729(+) (htrA) [Latilactobacillus sakei strain TMW 1.1398]
ATGAATCAAAATTCAGGATTAATGAAAACAGCGATTGTTGTGGTTATTTCAGCGTTGATTGGTGGTGGCGCAGCCTATGC
CGGTTTTTCTCGACTCGGCAATTCGGCCAATGACGTCACGACTGCAACGCAGACGCCTACTAAAGCGGGGGCAACTAAGA
TTAGTAACATCAAAGTGAACTCATCATCACAAACGACAACCGCCTTCCAAAAGGTTAATACATCAGTTGTATCCGTTGTG
AACTTACAAAAACAACAACAATCAACCGGTGACCTGAGTTCATTATTTGGTTCAGGGAGCACTGACAGCAATAGCAGTTC
TTCTAAGAGCAGTAGCAGTGATTTAGAAGAATCCAGTGAAGGTTCAGGTTTAATCTACGAGAAAAAAGACGGCAAAGCTT
ACATCGTGACGAATAATCACGTGGTTGCTGGTTCTGATAAAATCGAAGTCATTTTGAGTGATGGCACAAAATTGGAAGCT
AGTTTAGTTGGGACAGATGCTGTTTCTGATTTGGCTGTCTTAAAAATTAACGGGACTAAAGTGAAGAAGACGGCAACGTT
TGGTGATTCAGATAGTATCAAAGCTGGTGAATCAGTTCTTGCGATCGGCTCACCATTGGGCTCAGAATACGCAACTTCTG
TCACACAAGGGATTATTTCTGCTAAGAAACGGACCATTGATGTGACAGACGAAACAACCGGCCAAACAACTGGTCAAGCA
ACTGTTATTCAAACTGATACAGCGATTAACCCTGGGAATTCAGGTGGCCCATTAGTCAACATGGCTGGTCAAGTCATTGG
GATTAATTCAATGAAATTAGCTTCAAATGGTGAAACGTCTGTTGAAGGGATGGGCTTTGCTATTCCAAGTAACGAAGTCG
TTAAAATTATTAACCAATTGGTGGCTAACGGGAAAGTGGTTAGACCAGCACTTGGGATTAGTGTGATTGATTTAACCAAT
ATTTCATCAACACAACAATCTTCAGTACTAAAATTACCATCATCCGTTAACAGCGGGGTAGTAGTGGCCTCAGTAACAAG
CAATTCAGTTGCTAAGAAGGCTGGTATCAGTAAGTATGATGTGATTGTCGGCTTAGGCGGCAAGACGGTTTCAAGTGTGG
CAGACTTACACACAATTCTATATAGTTACGCAATGAACAGCACAACTGAAATTCAGTACTATCATAATGGCAGCTTGAAA
AAAGCGAATGTTAAACTCACACAAGCAGCTTCATCAGATAGTACGACAACAACTAAACAAACGAACTAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (121-268)

• Peptidase family M50 (Peptidase_M50) (256-413)

• PDZ domain (PDZ_2) (309-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	45.074	96.209	0.434
htrA	Streptococcus gordonii str. Challis substr. CH1	43.237	98.104	0.424
htrA	Streptococcus mutans UA159	46.237	88.152	0.408
htrA	Streptococcus pneumoniae TIGR4	49.284	82.701	0.408
htrA	Streptococcus pneumoniae R6	49.284	82.701	0.408
htrA	Streptococcus pneumoniae Rx1	49.284	82.701	0.408
htrA	Streptococcus pneumoniae D39	49.284	82.701	0.408