Detailed information NTG0166352

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BG483_RS08900
• Genome accession: NZ_CP017099
• Coordinates: 1894156..1894827 (-)
• Length: 223 a.a.
• NCBI ID: WP_003090494.1
• Uniprot ID: A0A0H2ZC88
• Organism: Pseudomonas aeruginosa strain DN1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1889156..1899827

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BG483_RS34695	-	1890493..1891512 (+)	1020	Protein_1718	chemotaxis protein	-
BG483_RS34700	-	1891882..1892418 (+)	537	Protein_1719	methyl-accepting chemotaxis protein	-
BG483_RS34215	-	1892423..1892590 (-)	168	WP_171430717.1	hypothetical protein	-
BG483_RS08895 (BG483_08495)	carS	1892822..1894159 (-)	1338	WP_003090493.1	two-component system sensor histidine kinase CarS	-
BG483_RS08900 (BG483_08500)	ciaR	1894156..1894827 (-)	672	WP_003090494.1	two-component system response regulator CarR	Regulator
BG483_RS08905 (BG483_08505)	-	1894827..1895141 (-)	315	WP_003097704.1	PepSY domain-containing protein	-
BG483_RS08910 (BG483_08510)	-	1895141..1895449 (-)	309	WP_003090497.1	PepSY domain-containing protein	-
BG483_RS08915 (BG483_08515)	-	1895664..1896746 (+)	1083	WP_003143813.1	hypothetical protein	-
BG483_RS08920 (BG483_08520)	-	1896773..1897666 (+)	894	WP_003110080.1	hypothetical protein	-
BG483_RS08925 (BG483_08525)	-	1897650..1897916 (+)	267	WP_003090500.1	DUF5329 domain-containing protein	-
BG483_RS08930 (BG483_08530)	-	1897917..1899110 (-)	1194	WP_021264902.1	NnrS family protein	-
BG483_RS08935 (BG483_08535)	ppyR	1899097..1899354 (-)	258	WP_021264903.1	psl/pyoverdine operon transcriptional regulator PpyR	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 24729.20 Da
• Isoelectric Point: 5.8445

>NTDB_id=166352 BG483_RS08900 WP_003090494.1 1894156..1894827(-) (ciaR) [Pseudomonas aeruginosa strain DN1]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide

• Length: 672 bp

>NTDB_id=166352 BG483_RS08900 WP_003090494.1 1894156..1894827(-) (ciaR) [Pseudomonas aeruginosa strain DN1]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAGCCCTACGACCTGATCATTCTCGACCTCGGCC
TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGCCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAACGCATCGATGGGCTCAAGGCCGGTGCCGACGACTATCTGACCAAGCCGTTCCATCCGGAAGA
GTTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGTCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-216)

3D structure

• AlphaFold DB: A0A0H2ZC88

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	37.727	98.655	0.372
ciaR	Streptococcus pneumoniae Rx1	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae D39	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae R6	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae TIGR4	37.273	98.655	0.368
micA	Streptococcus pneumoniae Cp1015	35.683	100	0.363
vicR	Streptococcus mutans UA159	35.526	100	0.363