Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   A7J08_RS06305 Genome accession   NZ_CP017088
Coordinates   1262832..1264190 (+) Length   452 a.a.
NCBI ID   WP_148115784.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1257832..1269190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS06280 (A7J08_06115) - 1258625..1259038 (-) 414 Protein_1168 IS982 family transposase -
  A7J08_RS06285 (A7J08_06120) - 1259646..1259876 (-) 231 WP_014638205.1 hypothetical protein -
  A7J08_RS06290 (A7J08_06125) - 1259892..1260101 (-) 210 WP_014638206.1 Blp family class II bacteriocin -
  A7J08_RS06295 (A7J08_06130) - 1260118..1260369 (-) 252 WP_014638207.1 bacteriocin -
  A7J08_RS06300 (A7J08_06135) comA/nlmT 1260668..1262821 (+) 2154 WP_148115783.1 peptide cleavage/export ABC transporter Regulator
  A7J08_RS06305 (A7J08_06140) comB 1262832..1264190 (+) 1359 WP_148115784.1 bacteriocin secretion accessory protein Regulator
  A7J08_RS06310 - 1264292..1264453 (+) 162 WP_014638210.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  A7J08_RS06315 (A7J08_06145) - 1264621..1265964 (-) 1344 WP_105105954.1 GHKL domain-containing protein -
  A7J08_RS06320 (A7J08_06150) comE/blpR 1265975..1266715 (-) 741 WP_014638212.1 response regulator transcription factor Regulator
  A7J08_RS06325 (A7J08_06155) - 1266727..1267059 (-) 333 WP_014638213.1 LytTR family DNA-binding domain-containing protein -
  A7J08_RS10630 - 1267252..1267638 (+) 387 WP_014638214.1 hypothetical protein -
  A7J08_RS10635 - 1267580..1269165 (-) 1586 Protein_1179 SAG1250 family conjugative relaxase -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 50542.76 Da        Isoelectric Point: 4.7191

>NTDB_id=166039 A7J08_RS06305 WP_148115784.1 1262832..1264190(+) (comB) [Streptococcus suis strain SRD478]
MNPNLFKSAEFYQRRYHNFATLLIVPLMLLLGFLLIFAFLAKKEVTVTSQGEITPTKVIASIQSTSNNPIITNNLSNNQL
IQKGDLIIQYSETMESSQKKALETHLETLNRQKTGIATLIDSLEQGTNLFTGEDEFGYIYTFNNFIKQFQDLELGISKVN
TEVSNQATIAGNTVAAIDTQINNLNQQIAEYEELYQAIINKSDKLSDGNPHQATLNNYLTQTQQNTDASLENQYVTQINQ
SITSIESSINSLNIQKASTGSVSTYDNSLGTKIEVLRTQFLQSASQQETTIDNQITELTTQLDQANIQLKNNKILASETG
IVQLNNDFEGHNLIPSGSDIAQIYPDIADTKKVLITYYVTSDYVSLLKEDQPVRLSLEKVGNQNLTVIGKIQSIDKTATK
TEQGNLFKIEALAQLSDKESKLVQYGLQGRVTTVTAKKTYFDYYKDKILNNF

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=166039 A7J08_RS06305 WP_148115784.1 1262832..1264190(+) (comB) [Streptococcus suis strain SRD478]
ATGAACCCAAATCTTTTTAAAAGTGCTGAATTTTATCAGCGACGTTACCATAATTTTGCCACACTCTTAATTGTCCCTTT
GATGTTATTGCTTGGTTTTCTTCTTATCTTCGCATTTTTAGCTAAAAAAGAAGTTACTGTCACCTCTCAAGGTGAGATTA
CACCTACTAAGGTTATCGCCTCCATTCAATCCACCAGTAATAACCCAATTATTACCAATAATCTCAGCAACAACCAGCTT
ATCCAGAAAGGTGACCTCATTATTCAATATTCAGAGACCATGGAAAGTTCTCAGAAAAAAGCTTTAGAAACACACTTAGA
AACGCTTAACAGGCAAAAAACTGGGATTGCGACACTTATTGATAGCCTGGAGCAAGGAACAAATCTTTTTACAGGAGAGG
ATGAGTTTGGCTACATCTATACTTTTAACAACTTCATCAAACAGTTCCAAGATCTTGAACTAGGCATTTCAAAAGTCAAT
ACTGAAGTTAGTAATCAAGCAACAATTGCTGGTAATACTGTTGCTGCTATTGATACCCAAATCAATAATCTCAACCAGCA
AATCGCCGAGTATGAAGAACTCTACCAAGCTATTATCAATAAGAGCGACAAACTATCTGACGGAAATCCACATCAAGCGA
CCCTAAATAATTATTTAACTCAAACCCAACAAAATACAGACGCTTCACTAGAAAATCAATACGTCACTCAGATTAATCAA
AGTATCACTTCTATTGAATCTTCAATTAATAGCTTAAATATCCAAAAAGCCAGTACAGGAAGTGTCTCTACCTATGATAA
TAGTTTAGGCACAAAGATAGAAGTATTAAGAACACAGTTCTTACAAAGTGCCTCTCAACAAGAAACTACAATCGACAATC
AAATCACTGAACTTACAACTCAATTGGACCAAGCTAATATTCAGTTAAAAAATAATAAAATCTTAGCTTCTGAAACAGGC
ATTGTGCAATTAAATAACGACTTTGAGGGACATAATCTTATTCCTAGCGGAAGTGATATCGCTCAAATCTACCCAGATAT
TGCCGATACAAAAAAAGTTCTTATTACCTACTATGTTACCTCAGACTATGTTTCCCTACTAAAGGAAGACCAGCCTGTTC
GACTTAGCCTGGAAAAAGTAGGAAATCAAAATCTCACAGTTATTGGAAAGATTCAGTCCATAGATAAAACAGCTACCAAG
ACGGAGCAAGGAAATCTTTTCAAAATTGAAGCTCTCGCTCAGTTATCAGATAAGGAGAGCAAGCTTGTTCAATATGGGCT
TCAAGGACGTGTCACAACCGTCACTGCAAAGAAAACTTACTTTGACTACTATAAAGATAAGATTTTAAATAACTTCTAA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(314-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

36.726

100

0.367
  comB Streptococcus mitis NCTC 12261

36.585

99.779

0.365
  comB Streptococcus pneumoniae Rx1

36.504

100

0.365
  comB Streptococcus pneumoniae D39

36.504

100

0.365
  comB Streptococcus pneumoniae R6

36.504

100

0.365