Detailed information NTG0166038

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: A7J08_RS06300
• Genome accession: NZ_CP017088
• Coordinates: 1260668..1262821 (+)
• Length: 717 a.a.
• NCBI ID: WP_148115783.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SRD478
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1255668..1267821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J08_RS06265 (A7J08_06100)	-	1256133..1256582 (+)	450	WP_024381709.1	MarR family transcriptional regulator	-
A7J08_RS06270 (A7J08_06105)	-	1256645..1257190 (+)	546	WP_053867333.1	NADPH-dependent FMN reductase	-
A7J08_RS06275 (A7J08_06110)	glf	1257260..1258402 (-)	1143	WP_024402792.1	UDP-galactopyranose mutase	-
A7J08_RS06280 (A7J08_06115)	-	1258625..1259038 (-)	414	Protein_1168	IS982 family transposase	-
A7J08_RS06285 (A7J08_06120)	-	1259646..1259876 (-)	231	WP_014638205.1	hypothetical protein	-
A7J08_RS06290 (A7J08_06125)	-	1259892..1260101 (-)	210	WP_014638206.1	Blp family class II bacteriocin	-
A7J08_RS06295 (A7J08_06130)	-	1260118..1260369 (-)	252	WP_014638207.1	bacteriocin	-
A7J08_RS06300 (A7J08_06135)	comA/nlmT	1260668..1262821 (+)	2154	WP_148115783.1	peptide cleavage/export ABC transporter	Regulator
A7J08_RS06305 (A7J08_06140)	comB	1262832..1264190 (+)	1359	WP_148115784.1	bacteriocin secretion accessory protein	Regulator
A7J08_RS06310	-	1264292..1264453 (+)	162	WP_014638210.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
A7J08_RS06315 (A7J08_06145)	-	1264621..1265964 (-)	1344	WP_105105954.1	GHKL domain-containing protein	-
A7J08_RS06320 (A7J08_06150)	comE/blpR	1265975..1266715 (-)	741	WP_014638212.1	response regulator transcription factor	Regulator
A7J08_RS06325 (A7J08_06155)	-	1266727..1267059 (-)	333	WP_014638213.1	LytTR family DNA-binding domain-containing protein	-
A7J08_RS10630	-	1267252..1267638 (+)	387	WP_014638214.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80585.58 Da
• Isoelectric Point: 7.3826

>NTDB_id=166038 A7J08_RS06300 WP_148115783.1 1260668..1262821(+) (comA/nlmT) [Streptococcus suis strain SRD478]
MTSYKHTFVPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAQEMGFETRAIQADMTLFDMDDV
PYPFIAHVNKEGKLQHYYVVYKARKNYILIGDPDPTVKVTKMSKERFASEWTGVAIFLAPEPRYKPHKDKKNGLMSFLPL
IFKQRSLIFYIVIASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILTIVGSVLLVQNTKLFLLSLISIPIYIV
IIFAFMKPFEKMNNNVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFKLSKYSILQGALKQGAQL
ILNVIILWSGAQLVMNGAISIGQLITFNTLLAYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFQNRQTLTDTQFL
HGDIEFEDLSYQYGFGRDTLSDINLTIKQGDKVSLVGISGSGKTTLAKMIVNFYDPYKGKISLNHHDLKMIDKKVLRQHI
NYLPQQAYIFSGSILENLTLGANQAISQEDILKACEIAEIRKDIEQMPMDYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVINNLMVMSDKTIIFVAHRLSISERTHQVIVLDQGTIIETGSHNELMAKQGFYYHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=166038 A7J08_RS06300 WP_148115783.1 1260668..1262821(+) (comA/nlmT) [Streptococcus suis strain SRD478]
ATGACATCATATAAACATACTTTTGTACCACAAATAGACGCTAGAGACTGCGGTGTTGCAGCGCTAGCTTCTATTGCCAA
ATTTTATGGCTCGGATTATTCCCTCGCACATTTACGAGAGTTGGCTAAGACCAATAAAGAAGGAACAACAGCCCTTGGAA
TTGTTAAAGCTGCCCAAGAAATGGGGTTTGAAACGAGAGCCATTCAAGCTGATATGACCTTATTTGATATGGATGATGTC
CCTTATCCTTTTATTGCCCATGTTAATAAAGAGGGAAAACTCCAACATTATTATGTTGTCTATAAGGCTAGAAAAAATTA
TATCCTTATTGGAGACCCTGACCCGACCGTCAAAGTTACCAAGATGTCCAAAGAGCGCTTTGCGTCTGAGTGGACAGGTG
TTGCTATTTTTTTAGCACCCGAACCTAGATATAAGCCCCATAAGGATAAAAAGAATGGCTTGATGAGTTTTCTACCCTTG
ATTTTCAAACAACGGTCTCTCATCTTTTACATCGTCATAGCAAGCCTGCTTGTTACTTTGATTAATATCGGTGGTTCCTA
CTATCTACAAGGCATTTTAGATGAATACATCCCAAATCAGATGAAATCAACACTCGGAATTATCTCAATTGGTCTTATCA
TTACTTATATCCTTCAACAAATGATGAGTTTTTCACGGGATTATCTCTTAACTGTACTCAGTCAGAGATTAAGCATTGAT
GTGATTTTATCTTATATTCGCCATATCTTTGAGTTACCAATGTCTTTCTTTGCGACAAGGCGTACAGGGGAAGTCATTTC
ACGCTTCACAGATGCCAATTCCATCATTGACGCACTCGCTTCTACCATTCTCTCACTTTTTCTAGACGTTTCGATTTTAA
CAATTGTAGGTAGTGTACTACTCGTACAAAATACCAAACTCTTCCTACTATCTTTGATTTCCATTCCCATCTACATTGTC
ATCATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATAACAATGTCATGCAGAGCAACTCTATGGTCAGCTCAGCCAT
TATCGAAGATATCAATGGTATTGAAACCATTAAATCGCTGACTAGTGAAGAAAGTCGTTATCAGAAAATCGATAGCGAGT
TTGTAGATTACCTAGATAAATCCTTTAAACTCAGTAAATACTCTATCCTACAAGGAGCATTAAAACAAGGGGCACAGCTT
ATACTTAATGTTATTATCCTTTGGTCAGGTGCTCAATTGGTAATGAATGGAGCAATTTCTATCGGACAACTCATAACATT
CAACACGCTCCTAGCCTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACTAAGCTACAATCGGCTAAGGTTG
CTAATAATCGCCTCAATGAAGTTTATCTGGTTGAGTCCGAATTTCAAAATAGACAAACCTTGACCGATACGCAATTCTTA
CATGGAGATATAGAATTTGAAGATTTATCCTATCAATATGGTTTTGGTCGTGATACCTTATCCGACATCAATTTGACCAT
TAAACAAGGTGATAAAGTCAGTCTTGTCGGTATTAGTGGTTCAGGTAAGACAACTTTAGCCAAAATGATTGTTAATTTCT
ATGACCCCTACAAGGGAAAAATTTCCCTCAATCATCACGATCTTAAAATGATTGATAAGAAAGTCTTACGTCAGCACATC
AACTATCTTCCCCAACAAGCCTATATCTTTAGCGGTTCAATCTTAGAAAATCTAACCCTTGGCGCTAATCAGGCTATTAG
CCAAGAGGATATCCTGAAAGCATGTGAAATCGCTGAAATTAGAAAAGACATTGAACAAATGCCCATGGACTATCAAACAG
AACTATCTGATGGTGCTGGACTTTCTGGAGGACAAAAACAGCGAATCGCCCTTGCTAGGGCTCTCCTAACAAAAGCACCC
GTACTCATTCTAGATGAGGCCACAAGTGGGCTTGATGTACTGACTGAAAAGAAAGTTATCAATAATCTCATGGTCATGAG
CGATAAAACTATTATCTTTGTGGCTCATCGTCTCAGTATCTCCGAACGAACTCATCAAGTTATCGTACTTGACCAAGGAA
CCATTATTGAAACTGGCTCTCATAACGAATTAATGGCCAAACAAGGTTTTTATTATCATCTATTTAGCAAGTAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.136	99.163	0.725
comA	Streptococcus mitis NCTC 12261	69.058	99.163	0.685
comA	Streptococcus mitis SK321	68.636	99.163	0.681
comA	Streptococcus pneumoniae Rx1	68.354	99.163	0.678
comA	Streptococcus pneumoniae D39	68.354	99.163	0.678
comA	Streptococcus pneumoniae R6	68.354	99.163	0.678
comA	Streptococcus pneumoniae TIGR4	68.073	99.163	0.675
comA	Streptococcus gordonii str. Challis substr. CH1	66.434	99.721	0.662