Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AU077_RS08190 Genome accession   NZ_CP013688
Coordinates   1639067..1639822 (-) Length   251 a.a.
NCBI ID   WP_058621890.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1634067..1644822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS08170 (AU077_08170) - 1634448..1635680 (-) 1233 WP_014293971.1 cysteine desulfurase -
  AU077_RS08175 (AU077_08175) sufD 1635682..1636944 (-) 1263 WP_014293970.1 Fe-S cluster assembly protein SufD -
  AU077_RS08180 (AU077_08180) sufC 1637018..1637788 (-) 771 WP_014293969.1 Fe-S cluster assembly ATPase SufC -
  AU077_RS08185 (AU077_08185) - 1637902..1639065 (-) 1164 WP_014293968.1 glycosyltransferase family 4 protein -
  AU077_RS08190 (AU077_08190) mecA 1639067..1639822 (-) 756 WP_058621890.1 adaptor protein MecA Regulator
  AU077_RS08195 (AU077_08195) - 1639923..1640762 (-) 840 WP_014293966.1 undecaprenyl-diphosphate phosphatase -
  AU077_RS08200 (AU077_08200) - 1640814..1642709 (-) 1896 WP_058621891.1 DUF2207 domain-containing protein -
  AU077_RS08205 (AU077_08205) - 1642843..1644414 (+) 1572 WP_014293964.1 ABC transporter permease subunit -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28871.67 Da        Isoelectric Point: 4.0307

>NTDB_id=164067 AU077_RS08190 WP_058621890.1 1639067..1639822(-) (mecA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSIMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMISKGDTEAHEKLGKIEEMMESAVEDVLTEQVQAEPTEEDINPSDYVHYV
LDFPTLEAVVSFAKAIDFPVEASELYKDGGLYHMTILLDLQNQPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVTKLKMIELI

Nucleotide


Download         Length: 756 bp        

>NTDB_id=164067 AU077_RS08190 WP_058621890.1 1639067..1639822(-) (mecA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATCTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAATAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTAACGCCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATT
AATAAAGAAATTAACTTTGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGATTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATTGAAGAAATGATGGAAAGTGCTG
TTGAGGATGTTCTCACAGAACAAGTTCAAGCAGAGCCAACAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTATCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGTGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCAACCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTACAAAATTAAAAATGATTGAGTTGATATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.935

98.805

0.661
  mecA Streptococcus thermophilus LMD-9

59.514

98.406

0.586
  mecA Streptococcus thermophilus LMG 18311

59.109

98.406

0.582
  mecA Streptococcus pneumoniae Rx1

48.221

100

0.486
  mecA Streptococcus pneumoniae D39

48.221

100

0.486
  mecA Streptococcus pneumoniae R6

48.221

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.486

Multiple sequence alignment