Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ATM98_RS08670 Genome accession   NZ_CP013651
Coordinates   1785574..1786320 (+) Length   248 a.a.
NCBI ID   WP_061564740.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1780574..1791320
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS08655 (ATM98_08660) - 1780668..1782230 (-) 1563 WP_061564737.1 ABC transporter substrate-binding protein/permease -
  ATM98_RS08660 (ATM98_08665) - 1782351..1784258 (+) 1908 WP_061564738.1 DUF2207 domain-containing protein -
  ATM98_RS08665 (ATM98_08670) - 1784572..1785408 (+) 837 WP_061564739.1 undecaprenyl-diphosphate phosphatase -
  ATM98_RS08670 (ATM98_08675) mecA 1785574..1786320 (+) 747 WP_061564740.1 adaptor protein MecA Regulator
  ATM98_RS08675 (ATM98_08680) - 1786317..1787474 (+) 1158 WP_061564741.1 MraY family glycosyltransferase -
  ATM98_RS08680 (ATM98_08685) sufC 1787561..1788331 (+) 771 WP_061564742.1 Fe-S cluster assembly ATPase SufC -
  ATM98_RS08685 (ATM98_08690) sufD 1788373..1789635 (+) 1263 WP_061564743.1 Fe-S cluster assembly protein SufD -
  ATM98_RS08690 (ATM98_08695) - 1789638..1790864 (+) 1227 WP_061564744.1 cysteine desulfurase -
  ATM98_RS08695 (ATM98_08700) - 1790851..1791285 (+) 435 WP_061564745.1 SUF system NifU family Fe-S cluster assembly protein -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28822.47 Da        Isoelectric Point: 4.0873

>NTDB_id=163433 ATM98_RS08670 WP_061564740.1 1785574..1786320(+) (mecA) [Streptococcus sp. A12]
MKMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQHLNFEDFSDLPDMEELSQMSPDEFIKTLEKTISEKSKGDGDAIRHLEAEELADENQLSEEDTPNHPVDTRYIYYILQF
SQLEEVIRFTKTVHYAVETSELYKMDGIYYLTVLIDLEGCPQDYPGWLLATMREYAEDTDTTRAVLQEHGHLLLVSDAIH
ELQKVNLV

Nucleotide


Download         Length: 747 bp        

>NTDB_id=163433 ATM98_RS08670 WP_061564740.1 1785574..1786320(+) (mecA) [Streptococcus sp. A12]
ATGAAGATGAAGCAAATCAGTGATTCAACCATTAAAATCACGATTCAATTAGAGGATTTAGAAGAACGAGGCATGGAAAT
GGCCGATTTTTTGGTGCCTCAAGAAAAAACAGAAGAATTTTTCTATACCATCTTGGATGAATTGGAAATGCCAGAAAGCT
TCTTAGACAGTGGCATGTTAAGTTTCCGAGTGACTCCTAAGCCGGATAAGCTCGACGTGTTTGTGACCAAATCAAAAATT
GATCAGCATCTAAATTTTGAAGATTTTTCCGACTTGCCTGATATGGAAGAATTGTCGCAAATGTCTCCAGACGAATTTAT
CAAGACCTTGGAAAAAACCATCTCTGAAAAGAGTAAGGGAGACGGCGATGCTATCCGTCATTTAGAAGCTGAGGAATTGG
CTGATGAGAATCAGCTTTCAGAAGAAGATACGCCGAATCATCCAGTAGATACACGGTATATTTATTATATCCTCCAGTTC
TCTCAGTTAGAAGAAGTGATTCGGTTTACAAAGACAGTTCATTATGCGGTCGAGACTTCGGAACTTTATAAAATGGACGG
GATTTACTATTTAACCGTCTTGATTGATTTGGAAGGGTGCCCGCAAGATTATCCAGGTTGGCTCTTGGCAACCATGCGTG
AATATGCAGAAGACACAGATACTACTAGAGCTGTCCTTCAGGAACATGGTCATCTCTTGCTCGTCTCAGATGCTATTCAC
GAACTACAAAAGGTTAATTTGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.854

99.194

0.653
  mecA Streptococcus pneumoniae D39

65.854

99.194

0.653
  mecA Streptococcus pneumoniae R6

65.854

99.194

0.653
  mecA Streptococcus pneumoniae TIGR4

65.854

99.194

0.653
  mecA Streptococcus mutans UA159

51.2

100

0.516
  mecA Streptococcus thermophilus LMD-9

45.783

100

0.46
  mecA Streptococcus thermophilus LMG 18311

45.382

100

0.456

Multiple sequence alignment